MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene yacO (MPN355)
Name 
yacO
Stable ID 
MPN355
Location 
423510 - 424238 -
Sequence 
    1  ATGAAGCGGA TGCAAGAAAC CAGTTTTTTA TTTGGTAGTA AGGCCTTTTT GGAAGCGTTA
   61  GATAACCAAC TGCAAATTAA AAAGGTCAAT TTATCTGATA AGCACCAAAA GCTGTTGGGC
  121  TTAATTAAGA AACGGGGATT GCGGTATGAA ATGCACTCCA GCCAGTGGTT TCACCAGCAG
  181  TTTCGCCACA TTAACCACCA GGAATTTGTT TGTGTAATCA ACCCTAACCA AATGCTCAAA
  241  ACAATTGAGC AGTTAATCCA AATTACAGAC AGCAAGTCCA CCAGTACCCT GGTAATGCTC
  301  CATGAGATCC AAGATCCGCA TAACTTTGGC GCCATCTTGC GCACCTGTAT GGCAGCTGAA
  361  GTGGATGGGA TTATCTTTAA AAAGCATAAC CAGGCGCCCA TTAACAGTAC CGTTATTAGA
  421  ACCAGTATGG GAACTGTCTT TTACCAGAAC TTAGTGCAGG TTACTAACCT CAGTTATGCC
  481  ATTACTACCC TGCAAAAACA CGGCTTTTGA ACGGTCGCTA CAACATTAGA TGAGCGCTTA
  541  AAGCCAAAAG ATTACCGCCA AGTAGACTTT GACAAGCGCA TTTTACTGGT AGGTAATGAA
  601  GATAAGGGCT TAAATGCACT ACTGTTAAAA AACGCTGATT TAAAGGTCAA AATTCCGATG
  661  AATCCCAAGC TCAACTCACT CAATGTTAGT GTTGCCGTGG GGATTATCTT GTTTGGATGA
  721  AAAAGCTAA
Download Sequence
Operon 
OP453
Operon location 
423575 - 424230
Protein (mpn355)
Name 
Probable 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB (EC 2.1.1.-)
Stable ID 
Mpn355
Molecular Weight 
26620
Isoelectric Point 
10
Localization 
Cytoplasm
Comment TrmH family. TRNA/rRNA 2-O ribose methyltransferase: G->Gm (2-O-methylguanosine). TRNA modification position 18
Sequence 
MKRMQETSFLFGSKAFLEALDNQLQIKKVNLSDKHQKLLGLIKKRGLRYEMHSSQWFHQQFRHINHQEFVCVINPNQMLK
TIEQLIQITDSKSTSTLVMLHEIQDPHNFGAILRTCMAAEVDGIIFKKHNQAPINSTVIRTSMGTVFYQNLVQVTNLSYA
ITTLQKHGFWTVATTLDERLKPKDYRQVDFDKRILLVGNEDKGLNALLLKNADLKVKIPMNPKLNSLNVSVAVGIILFGW
KS
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation mQETSFLFGSK 4 15 M
GENE/PROTEIN yacO (Domains Overview)
Click on the features to jump to domain info

 ExportIMG
Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
2-71 G3DSA:3.30.1330.30 (n.a.) NULL 0.0000037
4-76 SSF55315 (n.a.) NULL 0.0000084
6-242 TIGR00186 (IPR004441) RNA methyltransferase TrmH, group 3 Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006396'>'RNA' == '' ? '': 'RNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0006396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008173'>'RNA' == '' ? '': 'RNA'; 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008173)

0
9-79 SM00967 (IPR013123) RNA 2-O ribose methyltransferase, substrate bindin Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008168'>'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008168)

0.0053
10-77 PF08032 (IPR013123) RNA 2-O ribose methyltransferase, substrate bindin Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008168'>'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008168)

0.000000059
48-238 PTHR12029 (n.a.) NULL 0
48-238 PTHR12029:SF7 (n.a.) NULL 0
67-240 SSF75217 (n.a.) NULL 4.19969e-42
91-240 G3DSA:3.40.1280.10 (n.a.) NULL 1.82169e-44
97-238 PF00588 (IPR001537) tRNA/rRNA methyltransferase, SpoU Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006396'>'RNA' == '' ? '': 'RNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0006396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003723'>'RNA' == '' ? '': 'RNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003723) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008173'>'RNA' == '' ? '': 'RNA'; 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008173)

2.2e-37
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
1 238 237 - MAG0410 Mycoplasma agalactiae 1 226 7e-24 29.2887 253
97 238 141 - MAG0860 Mycoplasma agalactiae 98 236 0.0000000000003 29.8611 161
8 238 230 - MARTH_orf131 Mycoplasma arthritidis 3 223 2e-17 28.5714 197
1 238 237 - Caulobacter crescentus NA1000 22 259 0.0000000000005 25.0996 165
66 238 172 - Caulobacter crescentus NA1000 100 265 0.00000000002 29.6089 151
9 238 229 - MCJ_001760 Mycoplasma conjunctivae 4 222 1e-20 30 225
65 238 173 - MHO_0620 Mycoplasma hominis 56 224 0.000000000000005 30.6818 176
97 237 140 - MHO_2370 Mycoplasma hominis 97 233 0.00000000002 27.7778 144
4 238 234 - Lactococcus lactis subsp. lactis KF147 1 235 9e-21 27.0833 230
74 238 164 - Lactococcus lactis subsp. lactis KF147 90 250 0.00000000009 26.0606 143
97 238 141 - Bacillus subtilis subsp. subtilis 106 244 0.000000001 24.6479 137
98 238 140 - Bacillus subtilis subsp. subtilis 87 225 1e-19 31.6901 224
98 238 140 - Bacillus subtilis subsp. subtilis 100 238 1e-19 31.6901 224
97 238 141 - Bacillus subtilis subsp. subtilis 106 244 0.0000000003 25.3521 142
73 238 165 - b3651 Escherichia coli 1 159 0.0000002 24.8521 117
66 240 174 - b2581 Escherichia coli 170 339 0.0000000004 25 140
1 242 241 - MG252 Mycoplasma genitalium 1 242 <1e-50 57.438 750
50 238 188 - b4180 Escherichia coli 51 236 3e-17 28.7958 201
102 238 136 - Rv1644 Mycobacterium tuberculosis 115 251 0.0000000001 26.2774 144
83 237 154 - Rv3579c Mycobacterium tuberculosis 148 300 0.00000000009 26.5432 146
96 238 142 - Rv0881 Mycobacterium tuberculosis 131 275 0.0000000002 25.5172 143
95 238 143 - MCAP_0462 Mycoplasma capricolum subsp. capricolum 106 249 0.000000002 26.2069 130
83 238 155 - MCAP_0111 Mycoplasma capricolum subsp. capricolum 80 234 6e-25 35.0318 263
98 237 139 - MS53_0569 Mycoplasma synoviae 97 233 0.00000000000003 33.3333 169
9 241 232 - MS53_0358 Mycoplasma synoviae 5 228 1e-22 30.0429 242
54 241 187 - MHP7448_0640 Mycoplasma hyopneumoniae 7448 44 225 4e-17 30.8511 194
9 237 228 - MMOB1470 Mycoplasma mobile 4 222 9e-19 27.9476 209
94 242 148 - MMOB1200 Mycoplasma mobile 88 229 0.000002 28 103
84 238 154 - MSC_0960 Mycoplasma mycoides subsp. mycoides SC 81 234 6e-24 35.2564 254
95 238 143 - MSC_0508 Mycoplasma mycoides subsp. mycoides SC 106 249 0.0000000002 26.8966 138
92 238 146 - LIC_12832 Leptospira interrogans serovar Copenhage 122 265 0.00000003 25.6757 123
65 237 172 - LIC_12029 Leptospira interrogans serovar Copenhage 41 211 3e-17 29.9435 201
2 241 239 - MYCGA6780 Mycoplasma gallisepticum 16 256 <1e-50 42.623 458
98 238 140 - MYCGA4980 Mycoplasma gallisepticum 126 265 0.00000000002 30.8219 145
89 238 149 - MYPE230 Mycoplasma penetrans 86 232 3e-32 46.6667 326
95 237 142 - Mycoplasma pulmonis 101 238 0.00000000001 29.8611 149
10 237 227 - Mycoplasma pulmonis 6 223 2e-19 28.1385 215
External IDs
COG 
COG0566J
EC number 
2.1.1.-
Gene ID 
876924
GI 
13508094
GO 
Translation, ribosomal structure and biogenesis
Home COG 
J
InterPro 
IPR013123|RNA 2-O ribose methyltransferase, substrate binding
InterPro 
IPR004441|RNA methyltransferase TrmH, group 3
InterPro 
IPR001537|tRNA/rRNA methyltransferase, SpoU
Old MP number 
MP481
Pathway 
tRNA metabolism
PDB homologs 
1v2x_A
PDB homologs 
1ipa_A
PDB homologs 
1gz0_A
Pfam 
PF00588
Pfam 
PF08032
PID 
g1674172
RefSeq 
NP_110043.1
Swiss-Prot protein ID 
Y355_MYCPN
phylomeDB tree 
Y355_MYCPN
UniProt 
P75424
Transcription
IMAGE BROWSERS

OPERON OP453 (Genomic Overview)
Region:423575-424230

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STRING image

STRING of Mpn355STRING legend

PDB image(s)

1v2x

PDB 1v2x

1ipa

PDB 1ipa

1gz0

PDB 1gz0
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