MyMpn Project

Name	fruK
Stable ID	MPN079
Location	95268 - 96170 +
Sequence	1 ATGCTTAACC ACAACAGTAA AGTTTGAATA GTTAACTATG CTTGTGCGAT TGACTATTAC 61 TTAGATAAAC ACAAACAACA ACGCGGTGTG TTAACACCCG GTGGTAAGGG AATTAACATG 121 GCGATTGTAA TGGCTTTATT TGGCATCAAA CCAACCGTGT TAACCTTTTT GGGTCAACCT 181 ACTAAAGATT TATTCTTGCA GTTGTTAAAA CCGTACCAAC TGGACTTAGT TAGCTTTCCA 241 GCGACTACCC AAACACGGAT TAACGTGAAG CTGTTGGATG GTGCCCAAAC AACTGAAATT 301 AACGATGTCA CCCCGTTAAT TGAGGAACAA GCAGTCCATG AAATGATTGC TTACCTTAAG 361 GCTAACGTTA AGCCCAATGA CCTGTTGGTG TTGAACGGCC GTTTTTTACA ACGCGATTTA 421 GTTAAGTTGT TAGATGTTGC TTTTAGCTTA ACCAAGTATG TTGTATTAGA TGTTGATGAA 481 CCTCAACTAT TACAACTGTT AAACCAGCGC CAACCCTGGT TAATGAAACC GAACCGTGAT 541 GAGTTTGTAG CAATGGTTAA TGCAAATAAC AGTAACGTTG ACCAACAAGA GTTGGTGCAG 601 TTAATAAAGC AGTTTCAGAC TACACAGAAC TTATTAATGT CAGACGGCGC GCAGGGTGCT 661 TACTTCTTTG ATCAACAGCA ACTGTTATTT ATGGAAGCGA TTCCTCCCCA ACAGTTAGTT 721 TCCACTACGG GAGCGGGAGA TACATTGCTG GGTGTTTTCC TAGCTAACTT ACTGTTAGAT 781 AAGGATCCAG TGGGTAGTTT AAAGGTAGCG GTTAACTATG CTAGTGCTAC GATTAGCAAG 841 CTCGCTGTGG TCAACAGTAA TGACCAAATA GTGCTAAAAG CTACTAATTA TTACTATTTA 901 TAA
Download Sequence
Operon	OP29
Operon location	93165 - 96171

MLNHNSKVWIVNYACAIDYYLDKHKQQRGVLTPGGKGINMAIVMALFGIKPTVLTFLGQPTKDLFLQLLKPYQLDLVSFP

ATTQTRINVKLLDGAQTTEINDVTPLIEEQAVHEMIAYLKANVKPNDLLVLNGRFLQRDLVKLLDVAFSLTKYVVLDVDE

PQLLQLLNQRQPWLMKPNRDEFVAMVNANNSNVDQQELVQLIKQFQTTQNLLMSDGAQGAYFFDQQQLLFMEAIPPQQLV

STTGAGDTLLGVFLANLLLDKDPVGSLKVAVNYASATISKLAVVNSNDQIVLKATNYYYL

Name	Fructose 1-phosphate kinase (EC 2.7.1.56)
Stable ID	Mpn079
Molecular Weight	33000
Isoelectric Point	6
Localization	Cytoplasm
Comment	Base excision repair; hydorlizes dIMP as found by the canadian structural genomics consortium
Sequence	MLNHNSKVWIVNYACAIDYYLDKHKQQRGVLTPGGKGINMAIVMALFGIKPTVLTFLGQPTKDLFLQLLKPYQLDLVSFP ATTQTRINVKLLDGAQTTEINDVTPLIEEQAVHEMIAYLKANVKPNDLLVLNGRFLQRDLVKLLDVAFSLTKYVVLDVDE PQLLQLLNQRQPWLMKPNRDEFVAMVNANNSNVDQQELVQLIKQFQTTQNLLMSDGAQGAYFFDQQQLLFMEAIPPQQLV STTGAGDTLLGVFLANLLLDKDPVGSLKVAVNYASATISKLAVVNSNDQIVLKATNYYYL

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
5-286	PF00294 (IPR011611)	Carbohydrate/purine kinase			2.8026e-43
9-286	SSF53613 (n.a.)	NULL			2.4e-40
30-284	PTHR10584:SF37 (n.a.)	NULL			1.8e-29
30-284	PTHR10584 (n.a.)	NULL			1.8e-29
31-289	G3DSA:3.40.1190.20 (n.a.)	NULL			7.8e-35
34-58	PS00583 (IPR002173)	Carbohydrate/puine kinase, PfkB, conserved site			0

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
8	276	268	-	Lactococcus lactis subsp. lactis KF147	2	279	7e-18	25.8741	206
53	277	224	-	Bacillus subtilis subsp. subtilis	5	229	0.000000000007	26.4957	158
33	277	244	-	Bacillus subtilis subsp. subtilis	35	279	3e-16	27.8884	196
30	253	223	- b1723	Escherichia coli	34	262	0.000000005	24.5833	131
31	268	237	- b2168	Escherichia coli	36	276	0.0000000000009	27.3092	164
34	277	243	- MCAP_0852	Mycoplasma capricolum subsp. capricolum	36	285	1e-18	27.3438	209
4	277	273	- MCAP_0619	Mycoplasma capricolum subsp. capricolum	2	285	4e-18	27.2109	205
2	300	298	- MG063	Mycoplasma genitalium	4	300	<1e-50	56.5217	854
34	277	243	- MSC_0832	Mycoplasma mycoides subsp. mycoides SC	36	285	1e-18	27.3438	210
8	278	270	- MYPE7750	Mycoplasma penetrans	2	280	1e-29	28.4698	304

COG	COG1105G
EC number	2.7.1.56
Gene ID	877096
GI	13507818
GO	Carbohydrate transport and metabolism
Home COG	G
InterPro	IPR011611\|PfkB
InterPro	IPR002173\|Carbohydrate kinase, PfkB
Old MP number	MP076
Pathway	Metabolism energy, Glycolysis
PDB homologs	1rk2_A
PDB homologs	1gqt_A
PDB homologs	1rka_A
PDB homologs	1RKD
Pfam	PF00294
PID	g1673730
RefSeq	NP_109767.1
Swiss-Prot protein ID	FRUK_MYCPN
phylomeDB tree	FRUK_MYCPN
UniProt	P75038