MyMpn Project

Gene hmw2 (MPN310)

Name	hmw2
Stable ID	MPN310
Location	365468 - 370924 +
Sequence	1 ATGAATGATA CTGACAAGAA GTTCCCCTTG CAACCAGTTT ATGACACTGG GTTTGATGAT 61 GGGTATTTAC AGCGTGATTA TGAAAAGTGT TTAGAAAGTG CTGCTGCTAA TGATGCACAA 121 ACAGTGGAAC TACAAACCCA GCTGTTAGCA GAGATTAAAA ACCTTGAAAA CGAAATCAAG 181 GCCCTAAAGG CGCAGGAATC ACGCCAACCC GATCCGCACA ACAATGCCCG GATTCAAAGC 241 TTAGAAGCTA GCTTAAACCG TTTGGTCAAT GAGTACAACA ACTTTGAATT CCAAAAGAAC 301 TATATGGTTG ATCGGGTAGC AGAGTTAAAT AACAAAGCGC GTTTTTTTAA GGACGAATTA 361 AAGCGTCTCC AACAAGAAAA CGCCGCTTTT GTTAATTCCC GTTATGCCAA TTGAGCTGAC 421 TTTCAATCCA ACTATCAGCT CAAATTAGAC CAGTTTCAAG CGTTAATTGA CCAGCAAAAC 481 CAAACAATTA AGCAGCTCAA CGAACAGATT GCAGCTAACC AGGGCTTAAT TGATCAAAAC 541 GTACAGCGCT TACAGCAAAA CCACAGTTTA GACCAACAAG AACGTGACGC CTTACTGTAT 601 GAGGTTGACC ATTTATACAA CGAACTGTAC GAACTTGAAA ACCAAAAACG CTTAGTGGGC 661 ATCGAGTATG AAGCCACATA CCAGGACTTG GTGAGTGCGG ATGCGGAGTT GCAAAACGTT 721 TATGAAACAA TTGCCCAAAA CCAGGCCAAC TTCCAAAAGC AGTGTGATGC TTATTGAGCA 781 CAGCTCAAGC AAGTAGAACA GCAAATTCAA ACGACAAAGC AAGAATTGGT TGATGAAGAA 841 TCGACACTTA AGGTGCGTTT AAATGACGCT GATTTTTACA TTAACTCACG CTTAGCAGAA 901 TTAGATGATT TAACTAGCAA GATTAACGAA CGTGATTTTG TTTCTAAAGA ACAAGCTCAA 961 GACGTTAAAG CTAGTTTAGC TAACCTCACT AAGGAAAAAG AACGTTTGAG CGCTGAGAAG 1021 GATAGCTTTG AAAGGTTAAG GAACACCGCT TTAAACGACA TTAACCGAAT GGAGCAGGAA 1081 AACGCGTTGT TTGCTAAACA CTTAGAACAG CAACAATACG AGTTTGAAAG AAAGCAACAG 1141 GAAAGCTTAT TAAAGCTAGA AACAGAGCAT AAACAGCTCC AAAAACGAAT TGGTGAGTTC 1201 AAAATCGAGA GTGAAGCTAA AAGTGAAGCG TTACTGATAC AAGAACGTGA ACTGTTGGAA 1261 AAACGCCGGG AAATTGATGA TTTGTTAACC CAAGCCAGCT TGGAGTATGA ACAACAACGC 1321 CGGACGAATC AGGTCTTAAA GGAAAAGCAC CGTCAAGTCC AACAACACTT CCAAAACCTC 1381 GTGCATGCTA AAAAGAAATT GGATCAAAAG CGCCATTATT TAGCGGAACA AAAGCGGATT 1441 GATGAAGAAC AGATTTTTAA GTTAAAGGAA AAGATTGCCA CTGAACGCCG CGAATTGGAG 1501 AAGCTTTATC TAGTTAAAAA ACAAAAGCAA GACCAAAAGG AAAACGATTT ACTGATTTTT 1561 GAAAAACAGT TAAGGCAGTA CCAAGCTGAC TTTGAAAACG AAATAGAAGA GAAGCAAAAC 1621 GAGCTGTTTG CATCCCAAAA ATCACTCCAA AAATCGTTTA CACAACTCAA AAATAAGGAA 1681 GCGGAATTAA ACCAAAAGGC ACAAAAGATT GCAGAGGATT GAGCACATCT CAAACAAAAC 1741 AAACACCACC ACGCTGATCT AGAAATCTTT CTGGAGGGTG AATTTAACCA CTTACAACAA 1801 GAAAAGCACA AGCTGTTGGA AGCACGTACG CAGTTTGACA ACCGTGTCAG TTTGCTCTCA 1861 GCACGCTTTA AACAAAAACA AGCAGAATTA GTTAAACAAA AACAAAGCTT GGAACAACTC 1921 ACCGCTGCCT TTAATAAAGA GCAGGAAGCG GTAGAGCGTG ATTGGAAGGA TCGCTTAGCT 1981 AACTTAGAAA AGCAAAAGGA AATGCTGGGG GATAAGGTAC ACCAGTTTGA TGAAAATTCG 2041 CTCAATATTT CCAAAAAGCT AGCGGAGCGG GAGCTAGCGA TTAAATTTAA AGAAAAGGAG 2101 CTGGAGGCTG CACAAAAACA GCTAAGTTTA GACAACAACA ATAACGCTGG GTTAAAGTTG 2161 CAGTTAGATA AATTGAGCGA ATCACTCAAA ACGGAACGCC TGGAATTAGA AGCATCTAAA 2221 GAACGTATTT TGGATTTTTA CGATGAATCA TCACGCCGAA TTGCAGATTA TGAAAGCGAT 2281 TTACAAGCAC GCTTAGCTGA GGTTAAGACA CTAGAAAAAA ACCAGCAGGA AACAGCGGCT 2341 AAAAGTGAGC GCGAACTCAA AGTAGCCTTA GAAAAGTTAA ACCAAGCAAA AAAGGCTTTT 2401 TTACAAATTC GCAAACAGCA ATTGCTCGAA ATTGCTTCTG TAAAACAACA ACTAGCACAA 2461 AAAGCTAATT TGTTGAAAAA CCAACAAGCA GAGCTAGATA AGCAAACAGA AGAGTTAGAA 2521 GCAGCTTTTT TAGAGCAAGA TACGGACAAA AAGGAGTTGG AAAAAGCACT CCACAGCGTT 2581 AAGTCCAAGC AAGAATTATT AGAGCGCGAA CGCAGTTTTT TACTGCAAAA ACAACGTGAA 2641 TTTGCCGAAC ATGTAGCCGG CTTTAAGCGC CAAGTGCACT TTAAAACAAC GCAAATGCAG 2701 CGTTTAAGTG AGTTCAACAA ACAACAACAA AGTGAACAGA TAAAGCGCGA AACGGAGCTC 2761 AAAATTGCTT TTGCTGATCT AAAAAAGGAT TACCAGCTGT TTGAATTGCA AAAAAACCAG 2821 GAGTTCCAGC AAATCGAACA AAAGCACAAA GAACTAGAAC TATTAGCACA AAAACAGGCC 2881 GAACTCAAAC AGGAGTTAGA GCAAAAAGCA ACAGCTTTAG CTAGCCAAGA TCAAGACACA 2941 GTACAGGCCA AGCTAGATTT AGCGCGTCAA CAGCATGAAT TGGAATTGAG GCAAAATGCC 3001 TTTAACCAAG CTAGTCTTTC GCTCAACAAA CAACGCGAAC AGCTCACAAA CCAAGTCAAG 3061 GTATTGCACG GTGAGTTGAA AAAACGCCAT GAAAAGCTAA CTTTAAAGGA TCGTTTACTA 3121 GCTGAAAAGG AAAAGGATCA GCACAAAAAA GATGCAGAAA TTAACCAACG CTTTAAGCAG 3181 TTTGAAAATG AATACGCTGA TTTTGACCAA GCCAAAAAGC GCGAATTGCA AGAGTTAAAC 3241 CAAATCCGTC GAAACTTGGA GCAGAGCAAT GCATCACTGC TAAAGAAGCG CAACCAACTA 3301 ACGCTTGATT TTGCTTTACT ACGTAAAGTG CAACACAATA CGCAAACTAA CCGTGTCCAA 3361 CTCAACACGC AAATTAAGGA GTTTTTACTA GAGAAGAAGA ACTTTCAAAA GGCGAGTGAT 3421 GAAGCCGCTT TACAAAAAGC ACTGTTAATT AAACGCTTAC GTAGTTTTGC TTCTAAATTA 3481 CAGTTGCAAC GCGAAGCTTT AGCGATTCAA AAACTGGAAT TTGATAAGCG TGATGAACAA 3541 CAAAAGAGTG AGATTAACAA CGCTAAGTTA CAGTTAGAGC AGTTCAAACT AGAAAAGCAG 3601 AACTTTGATG AAGCGAAACA AAAGCAGTTA ATTGAGTTTA AGGATCAGTG CCAACGACTT 3661 GATGTTGAAA AACGTCTGTT AAAGCAAAAG TTAGTGCAGC TCAAAAACCT ATCTAAGAGC 3721 TATCTTACTT ACAAAAACCG TGCTGATCTG TCCCAACAAC AGCTGCAACA CAAGTATGCT 3781 AACTTACTGG AGTTGAAGGA AAAGCTGCAA ACCGCTAAGC GTGCCTTGGA CAAAAAACAC 3841 CGTGCCATTT ATGGCAAAAT GGCACAGTTT GTCAGTGAGC TCCGCCAAGA AAAGAAGCAG 3901 CTTTTAAGTG CGCAAAAACA AGTTGATGAC AAGTCACGTT TACTGGAACA AAACCAACGC 3961 CATTTACAAA ACCTTTCCAG TGAAACCAAA AAGAAACGCC AGTCTTTAGA GCATGACATT 4021 AATAAGTTTG ATCAAAGACG CAAGGAAGCG GTTTCTTCCA TTTTAAACTC GCACAAAAAA 4081 CTCAAGCAAA AAGAGGGAGA ATTGCAAGGC ATTTTGCAAA AGCTTAGCTT GAAAAAAACA 4141 CAAATTGAAC AAGAGTTTTC CAAGCTTTAT CAGCAACGCG AAAAGTTAGA TCGCCAACGC 4201 ACTACGCTCT CTAAACTCCA CAGAGAGCTA AAAGCCCAAA ATGAAGCTAC GGCACACAAA 4261 AATCGTGAAG TTTTAGAGAT TGAGAACTAT TACAAGAAGG AGTTGCAACG ACTCACCACG 4321 GAAAAGAGTG AGTTTGATAA CAACAAAAAT CGCTTGTTTG AATACTTCCG TAAAATTCGC 4381 AATGAAATTG AAAAGAAGGA AGCACACATT AAAACCGTTT TAGAAGAAAC ACAAAAAAAG 4441 CGTCACCTAG TCGAAACGGA AGCGGTCAAA CTACATTTAC AAAAGCAATC TATCATTTCT 4501 AAGGGTCAAG AACTTAAAGA AATCAAGGAA CGGGTTAGCC GTGACATTAG CCACACCAAC 4561 AAACAACGCG AAGAGTTAAA CAGCTTATTG CACCAAAACA AACTGTTGCA AAAGAATTTG 4621 GCTGAGCGTG AACGTGAAAT TAATAATAAG GATTCACTGT TAACCCAAAA GATTCAAACA 4681 GCTAAACAAA AGTTAAGCGA AAAAGAAGCA CGCATCTTAA AGCTGTTGGA AAAAATGCGT 4741 GCGGTAGAAC AGCAATACCA AGCGGAAATT ACCCGTTTAA AGACACGTAA TGCTGATTTG 4801 GAGAAGAATG ACAATAAGCA CTTATTTCCA CCGTTATTTA AAATTAACGG TAATGATATG 4861 AACTATCCTT ACCCATATCC TTGATTTTAT CCGCAACAAA AACAAGAAGA TAGTTCAAAC 4921 CAAATTCGCC ATCTTTTTGA ACAACAGTTG CAATTTATGC AACAGCGTTA CGAAAACGAA 4981 TTAACTGAGT TGCGTCGCCA ACGTGCTTTA TTGGAAAAAA AACTAGACCA AATTCAACTC 5041 GAATCACAGT TAAGCGCGAA GAAGAACGAC TTTGAAAAGG TTGAGCAAAT GATGCAAAAG 5101 TTGTTGGAAA AAACTGAGCA AAAACTCAGT GCCTTTGACC AAAAAATTAA TGCTTTGGCA 5161 GAACAGATTA ACACACAAAA AGCAGAGCAC GCTGACAGTG AAAAGCAACA GTTGTTACTA 5221 AGGATTGAAC AGTTAGAAAA GCAAAACCTA GCTCAAGCTG TTCAAACACC CCAACCAGTA 5281 CAACCAGTGG TACAAGCACC AGCTGTAGTA CCCCAAGTGA TCCAACCACA GGTAGTGCAG 5341 TCCCAACCAG CTTTTTTAGC AACGCAGCAA AGTATTTCTA AACAGCAACA AATCGCGCAA 5401 TTAAACGCTG AGATCAATAG TATTAAAAAG CTAATTGCCC AAAAAGCAGC TAAATAA
Download Sequence
Operon	OP124
Operon location	364188 - 373000

Protein (mpn310)

Name	Cytadherence high molecular weight protein 2 (Cytadherence accessory protein 2)
Stable ID	Mpn310
Molecular Weight	199980
Isoelectric Point	10
Localization	Cytoplasm
Comment	-
Sequence	MNDTDKKFPLQPVYDTGFDDGYLQRDYEKCLESAAANDAQTVELQTQLLAEIKNLENEIKALKAQESRQPDPHNNARIQS LEASLNRLVNEYNNFEFQKNYMVDRVAELNNKARFFKDELKRLQQENAAFVNSRYANWADFQSNYQLKLDQFQALIDQQN QTIKQLNEQIAANQGLIDQNVQRLQQNHSLDQQERDALLYEVDHLYNELYELENQKRLVGIEYEATYQDLVSADAELQNV YETIAQNQANFQKQCDAYWAQLKQVEQQIQTTKQELVDEESTLKVRLNDADFYINSRLAELDDLTSKINERDFVSKEQAQ DVKASLANLTKEKERLSAEKDSFERLRNTALNDINRMEQENALFAKHLEQQQYEFERKQQESLLKLETEHKQLQKRIGEF KIESEAKSEALLIQERELLEKRREIDDLLTQASLEYEQQRRTNQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLAEQKRI DEEQIFKLKEKIATERRELEKLYLVKKQKQDQKENDLLIFEKQLRQYQADFENEIEEKQNELFASQKSLQKSFTQLKNKE AELNQKAQKIAEDWAHLKQNKHHHADLEIFLEGEFNHLQQEKHKLLEARTQFDNRVSLLSARFKQKQAELVKQKQSLEQL TAAFNKEQEAVERDWKDRLANLEKQKEMLGDKVHQFDENSLNISKKLAERELAIKFKEKELEAAQKQLSLDNNNNAGLKL QLDKLSESLKTERLELEASKERILDFYDESSRRIADYESDLQARLAEVKTLEKNQQETAAKSERELKVALEKLNQAKKAF LQIRKQQLLEIASVKQQLAQKANLLKNQQAELDKQTEELEAAFLEQDTDKKELEKALHSVKSKQELLERERSFLLQKQRE FAEHVAGFKRQVHFKTTQMQRLSEFNKQQQSEQIKRETELKIAFADLKKDYQLFELQKNQEFQQIEQKHKELELLAQKQA ELKQELEQKATALASQDQDTVQAKLDLARQQHELELRQNAFNQASLSLNKQREQLTNQVKVLHGELKKRHEKLTLKDRLL AEKEKDQHKKDAEINQRFKQFENEYADFDQAKKRELQELNQIRRNLEQSNASLLKKRNQLTLDFALLRKVQHNTQTNRVQ LNTQIKEFLLEKKNFQKASDEAALQKALLIKRLRSFASKLQLQREALAIQKLEFDKRDEQQKSEINNAKLQLEQFKLEKQ NFDEAKQKQLIEFKDQCQRLDVEKRLLKQKLVQLKNLSKSYLTYKNRADLSQQQLQHKYANLLELKEKLQTAKRALDKKH RAIYGKMAQFVSELRQEKKQLLSAQKQVDDKSRLLEQNQRHLQNLSSETKKKRQSLEHDINKFDQRRKEAVSSILNSHKK LKQKEGELQGILQKLSLKKTQIEQEFSKLYQQREKLDRQRTTLSKLHRELKAQNEATAHKNREVLEIENYYKKELQRLTT EKSEFDNNKNRLFEYFRKIRNEIEKKEAHIKTVLEETQKKRHLVETEAVKLHLQKQSIISKGQELKEIKERVSRDISHTN KQREELNSLLHQNKLLQKNLAEREREINNKDSLLTQKIQTAKQKLSEKEARILKLLEKMRAVEQQYQAEITRLKTRNADL EKNDNKHLFPPLFKINGNDMNYPYPYPWFYPQQKQEDSSNQIRHLFEQQLQFMQQRYENELTELRRQRALLEKKLDQIQL ESQLSAKKNDFEKVEQMMQKLLEKTEQKLSAFDQKINALAEQINTQKAEHADSEKQQLLLRIEQLEKQNLAQAVQTPQPV QPVVQAPAVVPQVIQPQVVQSQPAFLATQQSISKQQQIAQLNAEINSIKKLIAQKAAK

Post translational modifications

Modification	Modified sequence	Relative start	Relative end	Amino acid
Oxidation	mNDTDKKFPLQPVYDTGFDDGYLQR	1	26	M
Oxidation	NTALNDINRmEQENALFAK	348	367	M
Oxidation	mEQENALFAK	357	367	M
Oxidation	QKEmLGDKVHQFDENSLNISKK	665	687	M
Oxidation	mAQFVSELR	1287	1296	M
Oxidation	mAQFVSELRQEK	1287	1299	M
Oxidation	mRAVEQQYQAEITR	1579	1593	M
Oxidation	HLFEQQLQFmQQr	1644	1657	M
Oxidation	HLFEQQLQFmQQR	1644	1657	M
Methylation	ALLEkK	1669	1675	K
Methylation	ALLEKk	1669	1675	K
Oxidation	KNDFEKVEQMmQK	1688	1701	M
Oxidation	KNDFEKVEQmmQK	1688	1701	M
Oxidation	KNDFEKVEQmMQK	1688	1701	M
Oxidation	VEQmMQK	1694	1701	M

GENE/PROTEIN hmw2 (Domains Overview)

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Domains (InterProScan)

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
1-1818	PIRSF004800 (IPR016430)	Cytadherence high molecular wieght protein 2			0

Protein Homology (BLASTP results)

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
1	1817	1816	- MG218	Mycoplasma genitalium	1	1803	<1e-50	54.1028	4489
10	1220	1210	- MYCGA3210	Mycoplasma gallisepticum	27	1276	4.99983e-42	23.6349	418

External IDs

Gene ID	876917
GI	13508049
GO	Cell envelope biogenesis, outer membrane
Home COG	M
Old MP number	MP526
Pathway	Adhesion�
Pathway	DNA repair? Cytoskeleton?
PDB homologs	1sjj_A
PDB homologs	1ii6_A
PDB homologs	1q0b_A
Pfam	PF06394
PID	g1674221
RefSeq	NP_109998.1
Swiss-Prot protein ID	HMW2_MYCPN
phylomeDB tree	HMW2_MYCPN
UniProt	P75471

Transcription

IMAGE BROWSERS

OPERON OP124 (Genomic Overview)

Region:364188-373000

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STRING image

STRING legend

PDB image(s)

PDB 1sjj

PDB 1ii6

PDB 1q0b