MyMpn Project

Name	mpn414
Stable ID	MPN414
Location	498076 - 499557 +
Sequence	1 ATGAAACCAA CAAGTCTCCC AAAAAACTTC ACCAACAACC CCGCCCCCAA GGCCGTCACC 61 GGCTTTAAGC TCGACAATGG CCGCGCGTAC CGGAAGTTAA ATGAAGCTTG ACCGGTGTAT 121 GAACCCCTGG ATTCGACGAA GGATGGCAAG GGGAAGGATA AAGATGGGTG AACCACTTCC 181 GGGGCGAGTG AGCCCAAAGG AGATGCCCCG TTGGTGAGCT CAACCGGGAG TCAAATGTCT 241 GCAGTCACAG ACAGTCAGCA ATCAGGTCAT AACAGTGGAT TGGTATCGCT TGCCCAGCGC 301 TCCACTACTG TTGCTGTCCA AAAAAGTGAC TCTTCTGGTT TTCAAGGCCA AGGCACAACC 361 GACAACAAAT TCCAAAAATA TTTAAACACC GCCCAGGCCT TGCACCAGAT GGGGGTGATA 421 GTGCCATCTT TGGAAACGTG ACCTGGTAAA CCAAGTACTG GAATCGCTAC CCGTGCTGGT 481 GGTGGTGTTT CAGTCCAAGC AGCGACCCGG CAATCGTCTT CTACAAATGA AGATTTGCCG 541 AATGTAATAA CACAGCTCTA TCATACCTCC ACGTCCCAAC TCGCTTACTT AAATGGCCAG 601 ATCGTTGTGA TGGGTTCAAA CGCGGTACCG AGTTTGTGGT ATTGGGTCGT GGATGAGCGA 661 ACCACGTCCG GGAGTGCGAC TTGATGAGCG AAGACACATT TGAACTTCGG CACTGAAGTT 721 CAAAAAAGCT TCGTTGAAAA CCAGTTGGGG TTTAAAGATG ACTCCAATTC GGATTCCAAA 781 AATTCGAATT TGAAGGCCCA AGACCTCACC CAACCCGCCT ACCTCATCAC TGGCCTTGAC 841 GTTGTCCAAG ACCACCTCGT CTTTGCGGCC TTCAAAGCGG GCGCGGTGGG GTATGATATG 901 ACGACTGATT CGAACGCTTC CACCAAAGAC CAAGCGCTCG CCTGGTCGAC CACGGCCGGG 961 TTGGACAGTG CTGGGGGGTA CAACAACCTG GTGGAAAACA CGGCCGGACT GAACGGCCCG 1021 ATTAACGACT TGTTTACCCT GCTCGACACC TTTGCCTATG TGACCCCGGT GAGTGGGATG 1081 AAAGGGGGGA GTCAGAATAA CGAAGAAGTG CAGACCAAGT ATCCCGTTAA GGATGATAGT 1141 AAGGCTTCCG CCAAAATTGC GTCCTTAATT AATGCCAGTC CACTCAACAG TTATGGGGAT 1201 GATGGGGTGA CCGTGTTTGA TGCGTTGGGC CTTAACTTTA ACTTTAAGTT GGACGAGGCG 1261 CGCTTGCCAT CGCGCACCGA CCAACTGCTT GTGTATGGGA TTGTAAACGA AAGTGAACTG 1321 AAGTCCGCGC GCGAAAATGC CCAGTCGACC TCCGATGATA ATTCAAACAC CAAAGTCAAG 1381 TGAACCAAAC CGCCTCGCAC TACCTCCCCG TGCCGTATTA CTACAGTGCC AATTTCCCCG 1441 AAGCGGGTAA CAGAAGAAGA GCGGAGCAGC GGGAATCATT AG
Download Sequence
Operon	OP174
Operon location	0 - 499550

MKPTSLPKNFTNNPAPKAVTGFKLDNGRAYRKLNEAWPVYEPLDSTKDGKGKDKDGWTTSGASEPKGDAPLVSSTGSQMS

AVTDSQQSGHNSGLVSLAQRSTTVAVQKSDSSGFQGQGTTDNKFQKYLNTAQALHQMGVIVPSLETWPGKPSTGIATRAG

GGVSVQAATRQSSSTNEDLPNVITQLYHTSTSQLAYLNGQIVVMGSNAVPSLWYWVVDERTTSGSATWWAKTHLNFGTEV

QKSFVENQLGFKDDSNSDSKNSNLKAQDLTQPAYLITGLDVVQDHLVFAAFKAGAVGYDMTTDSNASTKDQALAWSTTAG

LDSAGGYNNLVENTAGLNGPINDLFTLLDTFAYVTPVSGMKGGSQNNEEVQTKYPVKDDSKASAKIASLINASPLNSYGD

DGVTVFDALGLNFNFKLDEARLPSRTDQLLVYGIVNESELKSARENAQSTSDDNSNTKVKWTKPPRTTSPCRITTVPISP

KRVTEEERSSGNH

Approximately 4% of the limited M.�genitalium genome contains repeat sequences termed MgPar regions that have homology to mgpB and mgpC, which encode antigenic proteins associated with attachment. We have previously shown that mgpB sequences vary within a

Name	Putative mgpC-like protein MPN_414
Stable ID	Mpn414
Molecular Weight	54230
Isoelectric Point	6
Localization	SECRETOMEP
Comment	Approximately 4% of the limited M.�genitalium genome contains repeat sequences termed MgPar regions that have homology to mgpB and mgpC, which encode antigenic proteins associated with attachment. We have previously shown that mgpB sequences vary within a single strain of M.�genitalium in a pattern consistent with recombination between mgpB and MgPar sequences (Iverson-Cabral et�al.). In the current study, we show that mgpC heterogeneity similarly occurs within the type strain, G-37T, cultured in vitro and among cervical specimens collected from a persistently infected woman. In all cases, alternative mgpC sequences are indicative of recombination with MgPar regions
Sequence	MKPTSLPKNFTNNPAPKAVTGFKLDNGRAYRKLNEAWPVYEPLDSTKDGKGKDKDGWTTSGASEPKGDAPLVSSTGSQMS AVTDSQQSGHNSGLVSLAQRSTTVAVQKSDSSGFQGQGTTDNKFQKYLNTAQALHQMGVIVPSLETWPGKPSTGIATRAG GGVSVQAATRQSSSTNEDLPNVITQLYHTSTSQLAYLNGQIVVMGSNAVPSLWYWVVDERTTSGSATWWAKTHLNFGTEV QKSFVENQLGFKDDSNSDSKNSNLKAQDLTQPAYLITGLDVVQDHLVFAAFKAGAVGYDMTTDSNASTKDQALAWSTTAG LDSAGGYNNLVENTAGLNGPINDLFTLLDTFAYVTPVSGMKGGSQNNEEVQTKYPVKDDSKASAKIASLINASPLNSYGD DGVTVFDALGLNFNFKLDEARLPSRTDQLLVYGIVNESELKSARENAQSTSDDNSNTKVKWTKPPRTTSPCRITTVPISP KRVTEEERSSGNH

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
86-170	PD008387 (n.a.)	NULL			0
204-429	PF05220 (IPR007885)	MgpC			0

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
9	462	453	- MG192	Mycoplasma genitalium	192	571	<1e-50	42.7332	864

Gene ID	877297
GI	13508153
GO	Cell envelope biogenesis, outer membrane
Home COG	M
InterPro	Approximately 4% of the limited M.�genitalium genome contains repeat sequences termed MgPar regions that have homology to mgpB and mgpC, which encode antigenic proteins associated with attachment. We have previously shown that mgpB sequences vary within a
Old MP number	MP426
Pathway	Adhesion
Pfam	PF05220
Pfam	PF08372
PID	g1674111
RefSeq	NP_110102.1
Swiss-Prot protein ID	Y414_MYCPN
phylomeDB tree	Y414_MYCPN
UniProt	P75372