MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
>Omics>Metabolomics>Metabolic Reactions
Metabolic Reactions

These reactions are the result of the metabolic reconstruction based on a combination of in silico and experimental data, literature mining and sequence analysis. In this table, each metabolic enzymatic and transport reaction is shown, including KEGG references, the enzyme characteristics, the pathway and the equation of the reaction.
See also: Yus et al., 2009 and Wodke et al., 2013

Model ID Reaction ID Rev. KEGG ID Enzyme name Short EC number Stable Gene IDs Pathway Equation
M001 R001/R002 I R02628/R02738 phosphoenolpyruvate-protein phosphotransferase/PTS system, glucose-specific IIABC component PTSI/G 2.7.3.9/2.7.1.69 MPN627/MPN207 Glycolysis D-glucose[e] + phosphoenolpyruvate[c] --> D-glucose 6-phosphate[c] + pyruvate[c]
M002 R003 R R02740 glucose-6-phosphate isomerase PGI 5.3.1.9 MPN250 Glycolysis [c]: D-glucose 6-phosphate <==> D-fructose 6-phosphate
M003 R004 I R00756 6-phosphofructokinase PFK 2.7.1.11 MPN302 Glycolysis [c]: D-fructose 6-phosphate + ATP --> ADP + D-fructose 1,6-bisphosphate + H+
M004 R005 R R01068 fructose-bisphosphate aldolase FBA 4.1.2.13 MPN025 Glycolysis [c]: D-fructose 1,6-bisphosphate <==> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate
M005 R006 R R01015 triose-phosphate isomerase TIM 5.3.1.1 MPN629 Glycolysis [c]: D-glyceraldehyde 3-phosphate <==> dihydroxyacetone phosphate
M006 R007 R R01061 glyceraldehyde-3-phosphate dehydrogenase GAPDH 1.2.1.12 MPN430 Glycolysis [c]: NAD+ + orthophosphate + D-glyceraldehyde 3-phosphate <==> NADH + H+ + 1,3-bisphospho-D-glycerate
M007 R008 R R01512 phosphoglycerate kinase PGK 2.7.2.3 MPN429 Glycolysis [c]: 3-phospho-D-glycerate + ATP <==> ADP + 1,3-bisphospho-D-glycerate
M008 R009 R R01518 phosphoglycerate mutase PGM 5.4.2.1 MPN628 Glycolysis [c]: 2-phospho-D-glycerate <==> 3-phospho-D-glycerate
M009 R010 R R00658 enolase ENO 4.2.1.11 MPN606 Glycolysis [c]: 2-phospho-D-glycerate <==> phosphoenolpyruvate + H2O
M010 R011 I R00200 pyruvate kinase PYK 2.7.1.40 MPN303 Glycolysis [c]: ADP + phosphoenolpyruvate + H+ --> ATP + pyruvate
M011 R012 R R00703 L-lactate dehydrogenase LDH 1.1.1.27 MPN674 Pyruvate metabolism [c]: (S)-lactate + NAD+ <==> NADH + H+ + pyruvate
M012 R015 I R01699 pyruvate dehydrogenase E1 (acetyl-transferring) PDH-E1 1.2.4.1 MPN392/MPN393 Pyruvate metabolism [c]: lipoamide + H+ + pyruvate --> S-acetyldihydrolipoamide + CO2
M013 R016 R R02569 pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase) PDH-E2 2.3.1.12 MPN391 Pyruvate metabolism [c]: acetyl-CoA + dihydrolipoamide <==> S-acetyldihydrolipoamide + CoA
M014 R017 R R01698 pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase) PDH-E3 1.8.1.4 MPN390 Pyruvate metabolism [c]: dihydrolipoamide + NAD+ <==> lipoamide + NADH + H+
M015 R018 R R00230 phosphate acetyltransferase PTA 2.3.1.8 MPN428 Pyruvate metabolism [c]: acetyl-CoA + orthophosphate <==> acetyl phosphate + CoA
M016 R019 R R00315 acetate kinase ACK 2.7.2.1 MPN533 Pyruvate metabolism [c]: acetate + ATP <==> ADP + acetyl phosphate
M017 R020 R R00281 NADH oxidase NOX 1.6.99.3 MPN394 Pyruvate metabolism [c]: (2) NADH + oxygen + (2) H+ <==> (2) H2O + (2) NAD+
M018 R190 R R00086 ATP synthase ATPase 3.6.3.14 MPN597-MPN604 Energy metabolism (4) H+[e] + ADP[c] + orthophosphate[c] <==> H2O[c] + (3) H+[c] + ATP[c]
M019 R021 I R03076 fructose-permease IIBC component FRUA 2.7.1.69 MPN078 Alternative sugar metabolism D-fructose[e] + phosphoenolpyruvate[c] --> D-fructose 1-phosphate[c] + pyruvate[c]
M020 R022 I R02071 1-phosphofructokinase FRUK 2.7.1.56 MPN079 Alternative sugar metabolism [c]: D-fructose 1-phosphate + ATP --> ADP + D-fructose 1,6-bisphosphate + H+
M021 R023 I R02568 fructose-bisphosphate aldolase FBA 4.1.2.13 MPN025 Alternative sugar metabolism [c]: D-fructose 1-phosphate --> D-glyceraldehyde + dihydroxyacetone phosphate
M022 R024 R R01041 alcohol dehydrogenase ADH 1.1.1.1 MPN564 Alternative sugar metabolism [c]: glycerol + NAD+ <==> D-glyceraldehyde + NADH + H+
M023 R026 I R02630 fructose-permease IIBC component FRUA 2.7.1.69 MPN078 Alternative sugar metabolism D-mannose[e] + phosphoenolpyruvate[c] --> D-mannose 6-phosphate[c] + pyruvate[c]
M024 R028 R R01819 phosphomannose-6-phosphate isomerase MPI 5.3.1.8 ? Alternative sugar metabolism [c]: D-mannose 6-phosphate <==> D-fructose 6-phosphate
M025 R029 I R02704 PTS system, mannitol-specific component IIA MTLA 2.7.1.69 MPN651/MPN653 Alternative sugar metabolism mannitol[e] + phosphoenolpyruvate[c] --> pyruvate[c] + D-mannitol 1-phosphate[c]
M026 R030 R R00758 mannitol-1-phosphate 5-dehydrogenase MTLD 1.1.1.17 MPN652 Alternative sugar metabolism [c]: NAD+ + D-mannitol 1-phosphate <==> NADH + D-fructose 6-phosphate + H+
M027 R031 I R07671 PTS system, 3-keto-L-gulonate/L-ascorbate specific PTSA 2.7.1.69 MPN494-MPN496 Alternative sugar metabolism L-ascorbate[e] + phosphoenolpyruvate[c] + (2) H+[c] --> L-ascorbate 6-phosphate[c] + pyruvate[c]
M028 R032 R R07677 L-ascorbate-6-phosphate lactonase ULAG 3.1.1.- MPN497 Alternative sugar metabolism [c]: H2O + L-ascorbate 6-phosphate <==> 3-keto-L-gulonate 6-phosphate + (3) H+
M029 R033 I R07125 3-dehydro-L-gulonate-6-phosphate decarboxylase KGPDC 4.1.1.85 MPN493 Alternative sugar metabolism [c]: 3-keto-L-gulonate 6-phosphate + H+ --> CO2 + L-xylulose 5-phosphate
M030 R034 R R03244 L-ribulose-5-phosphate 3-epimerase ULAE 5.1.3.22 MPN492 Alternative sugar metabolism [c]: L-ribulose 5-phosphate <==> L-xylulose 5-phosphate
M031 R035 R R05850 L-ribulose-5-phosphate 4-epimerase ULAF 5.1.3.4 MPN498 Alternative sugar metabolism [c]: L-ribulose 5-phosphate <==> D-xylulose 5-phosphate
M032 R191 I R00086 D-ribose transporter RibABC 3.6.3.17 MPN258-MPN260 Pentose phosphate pathway D-ribose[e] --> D-ribose[c]
M033 R036 I R01051 ribokinase RBSK 2.7.1.15 ? Pentose phosphate pathway [c]: D-ribose + ATP --> ADP + D-ribose 5-phosphate + H+
M034 R037 R R01067  transketolase TKL 2.2.1.1 MPN082 Pentose phosphate pathway [c]: D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate <==> D-xylulose 5-phosphate + D-erythrose 4-phosphate
M035 R038 R R08575 transaldolase TAL 2.2.1.2 ? Pentose phosphate pathway [c]: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <==> D-erythrose 4-phosphate + D-fructose 6-phosphate
M036 R039 R R01641 transketolase TKL 2.2.1.1 MPN082 Pentose phosphate pathway [c]: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <==> D-xylulose 5-phosphate + D-ribose 5-phosphate
M037 R040 R R01529 ribulose-phosphate 3-epimerase RPE 5.1.3.1 MPN251 Pentose phosphate pathway [c]: D-ribulose 5-phosphate <==> D-xylulose 5-phosphate
M038 R041 R R01056 ribose-5-phosphate isomerase RPIA 5.3.1.6 MPN595 Pentose phosphate pathway [c]: D-ribose 5-phosphate <==> D-ribulose 5-phosphate
M039 R042 I R01049 ribose-phosphate diphosphokinase PRPS 2.7.6.1 MPN073 Pentose phosphate pathway [c]: D-ribose 5-phosphate + ATP --> AMP + 5-phospho-alpha-D-ribose 1-diphosphate + H+
M040 R043 R R01057 phosphopentomutase DEOB 5.4.2.7 MPN066 Pentose phosphate pathway [c]: D-ribose 1-phosphate <==> D-ribose 5-phosphate + (2) H+
M041 R044 R R02749 phosphopentomutase DEOB 5.4.2.7 MPN066 Pentose phosphate pathway [c]: 2-deoxy-D-ribose 1-phosphate <==> 2-deoxy-D-ribose 5-phosphate
M042 R046 I R01066 deoxyribose-phosphate aldolase DERA 4.1.2.4 MPN063 Pentose phosphate pathway [c]: 2-deoxy-D-ribose 5-phosphate --> acetaldehyde + D-glyceraldehyde 3-phosphate
M043 R047 R R00228 acetaldehyde dehydrogenase ADH 1.2.1.10 MPN564 Alternative sugar metabolism [c]: acetaldehyde + NAD+ + CoA <==> acetyl-CoA + NADH + H+
M044 R192 R - glycerol uptake facilitator GlpF - MPN043 Alternative sugar metabolism glycerol[c] <==> glycerol[e]
M045 R049 I R00847 glycerol kinase GK 2.7.1.30 MPN050 Alternative sugar metabolism [c]: glycerol + ATP --> ADP + sn-glycerol 3-phosphate + H+
M046 R193 I - sn-glycerol-3-phosphate transporter GlyABC - MPN133-MPN136 Alternative sugar metabolism sn-glycerol 3-phosphate[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + H+[c] + sn-glycerol 3-phosphate[c]
M047 R186 R R00846 glycerol-3-phosphate oxidase GPO 1.1.3.21  MPN051 Lipid metabolism [c]: oxygen + sn-glycerol 3-phosphate <==> H2O2 + dihydroxyacetone phosphate
M048 R051 I R01010 spontaneus - - - Lipid metabolism [c]: H2O + dihydroxyacetone phosphate --> dihydroxyacetone + orthophosphate
M049 R052 I R01011 glycerone kinase DHAK 2.7.1.29 MPN547 Lipid metabolism [c]: dihydroxyacetone + ATP --> ADP + dihydroxyacetone phosphate + H+
M050 R053 I R00851 glycerol-3-phosphate O-acyltransferase GPAM 2.3.1.15 MPN350/MPN546 Lipid metabolism [c]: ACP-R (Mpn) + sn-glycerol 3-phosphate --> 1-acyl-glycerol 3-phosphate (Mpn) + acyl carrier protein
M051 R054 I R02241 1-acyl-sn-glycerol-3-phosphate acyltransferase AGPAT 2.3.1.51 MPN299 Lipid metabolism [c]: ACP-R (Mpn) + 1-acyl-glycerol 3-phosphate (Mpn) --> phosphatidic acid (Mpn) + acyl carrier protein
M052 R055 I R01799 phosphatidate cytidylyltransferase CDP-DG 2.7.7.41 MPN637 Lipid metabolism [c]: phosphatidic acid (Mpn) + CTP + H+ --> CDP-diacylglycerol (Mpn) + pyrophosphate
M053 R056 I R01801 phosphatidylglycerophosphate synthase PGP 2.7.8.5 MPN253 Lipid metabolism [c]: CDP-diacylglycerol (Mpn) + sn-glycerol 3-phosphate --> CMP + phosphatidylglycerol 3-phosphate (Mpn) + H+
M054 R057 I R02029 phosphatidylglycerophosphatase PGPB 3.1.3.27 ? Lipid metabolism [c]: H2O + phosphatidylglycerol 3-phosphate (Mpn) --> orthophosphate + phosphatidylglycerol (Mpn)
M055 R058 I R02030 cardiolipin synthase CLS 2.7.8.- ? Lipid metabolism [c]: CDP-diacylglycerol (Mpn) + phosphatidylglycerol (Mpn) --> cardiolipin (Mpn) + CMP + H+
M056 R059 I R02239 phosphatidate phosphatase PPT 3.1.3.4 MPN455 Lipid metabolism [c]: H2O + phosphatidic acid (Mpn) --> diacylglycerol (Mpn) + orthophosphate
M057 R060 R R00959 phosphoglucomutase PGM 5.4.2.2 MPN066 Lipid metabolism [c]: D-glucose 1-phosphate <==> D-glucose 6-phosphate
M058 R061 R R00289 UDP glucose pyrophosphorylase UGP 2.7.7.9 MPN667 Lipid metabolism [c]: D-glucose 1-phosphate + UTP + H+ <==> UDP-glucose + pyrophosphate
M059 R062 R R00291 UDP-glucose 4-epimerase UGE 5.1.3.2 MPN257 Lipid metabolism [c]: UDP-glucose <==> UDP-galactose
M060 R063/R064 I - glycosyl transferase GTF - MPN483 Lipid metabolism [c]: diacylglycerol (Mpn) + (3) UDP-galactose + (3) UDP-glucose --> glycolipid (Mpn) + (6) H+ + (6) UDP
M061 R178 I R01021 choline kinase CHK 2.7.1.32 MPN532 Lipid metabolism [c]: choline + ATP --> ADP + H+ + choline phosphate
M062 R180 I R01890 choline-phosphate cytidylyltransferase PCT 2.7.7.15 MPN336 Lipid metabolism [c]: CTP + H+ + choline phosphate --> CDP-choline + pyrophosphate
M063 R182 R R01030 glycerophosphoryl diester phosphodiesterase GlpQ 3.1.4.46 MPN420 Lipid metabolism [c]: sn-glycero-3-phosphocholine + H2O <==> choline + sn-glycerol 3-phosphate + H+
M064 R187 R R01309 phosphatidylcholine acylhydrolase PldB 3.1.1.5 MPN445 Lipid metabolism [c]: phosphatidylcholine + (2) H2O <==> sn-glycero-3-phosphocholine + (2) fatty acid (Mpn)
M065 R065 R R00190 adenine phosphoribosyltransferase APRT 2.4.2.7 MPN395 Nucleotide metabolism [c]: AMP + pyrophosphate <==> adenine + 5-phospho-alpha-D-ribose 1-diphosphate
M066 R066 R R01561 purine-nucleoside phosphorylase PNP 2.4.2.1 MPN062 Nucleotide metabolism [c]: adenosine + orthophosphate + (2) H+ <==> D-ribose 1-phosphate + adenine
M067 R067 I R00183 5'-nucleotidase NT5 3.1.3.5 ? Nucleotide metabolism [c]: H2O + AMP --> adenosine + orthophosphate
M068 R068 R R00127 adenylate kinase AK 2.7.4.3 MPN185 Nucleotide metabolism [c]: AMP + ATP <==> (2) ADP
M069 R069 I R02017 Ribonucleoside-diphosphate reductase RDR 1.17.4.1 MPN322-MPN324 Nucleotide metabolism [c]: ADP + reduced thioredoxin --> dADP + H2O + oxidized thioredoxin
M070 R070 R R02016 thioredoxin-disulfide reductase TXNRD 1.8.1.9 MPN240 Nucleotide metabolism [c]: oxidized thioredoxin + H+ + NADPH <==> NADP+ + reduced thioredoxin
M071 R071/R084/ I - DNA-directed RNA polymerase RNAP - MPN516 Nucleotide metabolism [c]: (28) GTP + (25) UTP + (40) H2O + (18) CTP + (69) ATP --> (40) ADP + RNA (Mpn) + (40) orthophosphate + (40) H+ + (100) pyrophosphate
M072 R072 I R00004 inorganic diphosphatase PPA 3.6.1.1 MPN528 Nucleotide metabolism [c]: H2O + pyrophosphate --> (2) orthophosphate + H+
M073 R073 R R02557 purine-nucleoside phosphorylase PNP 2.4.2.1 MPN062 Nucleotide metabolism [c]: deoxyadenosine + orthophosphate <==> 2-deoxy-D-ribose 1-phosphate + adenine
M074 R074 R R02089 deoxyadenosine kinase DAK 2.7.1.76 MPN386 Nucleotide metabolism [c]: deoxyadenosine + ATP <==> ADP + H+ + dAMP
M075 R075 R R01547 adenylate kinase AK 2.7.4.3 MPN185 Nucleotide metabolism [c]: dAMP + ATP <==> dADP + ADP
M076 R076 I R01138 pyruvate kinase PYK 2.7.1.40 MPN303 Nucleotide metabolism [c]: phosphoenolpyruvate + dADP + H+ --> dATP + pyruvate
M077 R175 R - phosphoglycerate kinase PGK 2.7.2.3 MPN429 Nucleotide metabolism [c]: 3-phospho-D-glycerate + dATP <==> dADP + 1,3-bisphospho-D-glycerate
M078 R077/R089/ I - DNA-directed DNA polymerase DNAP - MPN034/MPN378 Nucleotide metabolism [c]: (20) dGTP + (140) H2O + (30) dTTP + (20) dCTP + (140) ATP + (30) dATP --> (140) ADP + DNA (Mpn) + (140) orthophosphate + (140) H+ + (100) pyrophosphate
M079 R078 R R01229 hypoxanthine-guanine phosphoribosyltransferase HPRT 2.4.2.8 MPN672 Nucleotide metabolism [c]: GMP + pyrophosphate <==> 5-phospho-alpha-D-ribose 1-diphosphate + guanine
M080 R079 R R02147 purine-nucleoside phosphorylase PNP 2.4.2.1 MPN062 Nucleotide metabolism [c]: guanosine + orthophosphate + (2) H+ <==> D-ribose 1-phosphate + guanine
M081 R080 I R01227 5'-nucleotidase NT5 3.1.3.5 ? Nucleotide metabolism [c]: GMP + H2O --> guanosine + orthophosphate
M082 R081 R R00332 guanylate kinase GUK 2.7.4.8 MPN246 Nucleotide metabolism [c]: GMP + ATP <==> ADP + GDP
M083 R082 I R02019 Ribonucleoside-diphosphate reductase RDR 1.17.4.1 MPN322-MPN324 Nucleotide metabolism [c]: reduced thioredoxin + GDP --> H2O + oxidized thioredoxin + dGDP
M084 R083 I R00430 pyruvate kinase PYK 2.7.1.40 MPN303 Nucleotide metabolism [c]: phosphoenolpyruvate + H+ + GDP --> GTP + pyruvate
M085 R176 R R01517 phosphoglycerate kinase PGK 2.7.2.3 MPN429 Nucleotide metabolism [c]: GTP + 3-phospho-D-glycerate <==> GDP + 1,3-bisphospho-D-glycerate
M086 R085 R R01969 purine-nucleoside phosphorylase PNP 2.4.2.1 MPN062 Nucleotide metabolism [c]: deoxyguanosine + orthophosphate <==> 2-deoxy-D-ribose 1-phosphate + guanine
M087 R086 R R01967 deoxyguanosine kinase DGK 2.7.1.113 MPN386 Nucleotide metabolism [c]: deoxyguanosine + ATP <==> ADP + H+ + dGMP
M088 R087 R R02090 guanylate kinase GUK 2.7.4.8 MPN246 Nucleotide metabolism [c]: ATP + dGMP <==> ADP + dGDP
M089 R088 I R01858 pyruvate kinase PYK 2.7.1.40 MPN303 Nucleotide metabolism [c]: phosphoenolpyruvate + dGDP + H+ --> dGTP + pyruvate
M090 R177 R - phosphoglycerate kinase PGK 2.7.2.3 MPN429 Nucleotide metabolism [c]: 3-phospho-D-glycerate + dGTP <==> dGDP + 1,3-bisphospho-D-glycerate
M091 R090 R R00966 uracil phosphoribosyltransferase UPRT 2.4.2.9 MPN033 Nucleotide metabolism [c]: UMP + pyrophosphate <==> uracil + 5-phospho-alpha-D-ribose 1-diphosphate
M092 R091 R R01876 uridine phosphorylase UPP 2.4.2.3 MPN064 Nucleotide metabolism [c]: orthophosphate + (2) H+ + uridine <==> uracil + D-ribose 1-phosphate
M093 R092 I R00963 5'-nucleotidase NT5 3.1.3.5 ? Nucleotide metabolism [c]: H2O + UMP --> orthophosphate + uridine
M094 R093 I R00964 uridine kinase UCK 2.7.1.48 MPN561 Nucleotide metabolism [c]: ATP + uridine --> ADP + UMP + H+
M095 R094 R R00158 uridylate kinase UMPK 2.7.4.22 MPN632 Nucleotide metabolism [c]: UMP + ATP <==> ADP + UDP
M096 R095 I R00659 pyruvate kinase PYK 2.7.1.40 MPN303 Nucleotide metabolism [c]: phosphoenolpyruvate + H+ + UDP --> UTP + pyruvate
M097 R096 I R02018 Ribonucleoside-diphosphate reductase RDR 1.17.4.1 MPN322-MPN324 Nucleotide metabolism [c]: reduced thioredoxin + UDP --> H2O + oxidized thioredoxin + dUDP
M098 R097 I R01878 cytidine deaminase CDA 3.5.4.5 MPN065 Nucleotide metabolism [c]: cytidine + H2O --> NH3 + uridine
M099 R100 I R00513 cytidine kinase UCK 2.7.1.48 MPN561 Nucleotide metabolism [c]: cytidine + ATP --> ADP + CMP + H+
M100 R101 I R00511 5'-nucleotidase NT5 3.1.3.5 ? Nucleotide metabolism [c]: H2O + CMP --> cytidine + orthophosphate
M101 R102 R R00512 cytidylate kinase CMPK 2.7.4.14 MPN476 Nucleotide metabolism [c]: CMP + ATP <==> ADP + CDP
M102 R103 I R00572 pyruvate kinase PYK 2.7.1.40 MPN303 Nucleotide metabolism [c]: phosphoenolpyruvate + CDP + H+ --> CTP + pyruvate
M103 R105 I R02024 Ribonucleoside-diphosphate reductase RDR 1.17.4.1 MPN322-MPN324 Nucleotide metabolism [c]: CDP + reduced thioredoxin --> H2O + oxidized thioredoxin + dCDP
M104 R106 I R01666 deoxycytidine kinase DCK 2.7.1.74 MPN386 Nucleotide metabolism [c]: deoxycytidine + ATP --> ADP + dCMP + H+
M105 R107 I R01664 5'-nucleotidase NT5 3.1.3.5 ? Nucleotide metabolism [c]: H2O + dCMP --> deoxycytidine + orthophosphate
M106 R108 R R01665 deoxycytidylate kinase CMPK 2.7.4.14 MPN476 Nucleotide metabolism [c]: dCMP + ATP <==> ADP + dCDP
M107 R109 I R02320 pyruvate kinase PYK 2.7.1.40 MPN303 Nucleotide metabolism [c]: phosphoenolpyruvate + dCDP + H+ --> dCTP + pyruvate
M108 R174 I R01878 deoxycytidine deaminase CDA 3.5.4.5 MPN065 Nucleotide metabolism [c]: H2O + deoxycytidine --> deoxyuridine + NH3
M109 R111 R R02484 uridine phosphorylase UPP 2.4.2.3 MPN064 Nucleotide metabolism [c]: deoxyuridine + orthophosphate <==> uracil + 2-deoxy-D-ribose 1-phosphate
M110 R112 I R02099 thymidine kinase TK 2.7.1.21 MPN044 Nucleotide metabolism [c]: deoxyuridine + ATP --> ADP + dUMP + H+
M111 R113 I R07297 5'-nucleotidase NT5 3.1.3.5 ? Nucleotide metabolism [c]: H2O + dUMP --> deoxyuridine + orthophosphate
M112 R189 R R02098 thymidylate kinase TMPK 2.7.4.9 MPN006 Nucleotide metabolism [c]: dUMP + ATP <==> ADP + dUDP
M113 R114 R R02101 thymidylate synthase THY 2.1.1.45 MPN320 Nucleotide metabolism [c]: 5,10-methylenetetrahydrofolate + dUMP <==> dTMP + dihydrofolate
M114 R115 R R01570 thymidine phosphorylase UPP 2.4.2.4 MPN064 Nucleotide metabolism [c]: thymidine + orthophosphate <==> 2-deoxy-D-ribose 1-phosphate + thymine
M115 R116 I R01567 thymidine kinase TK 2.7.1.21 MPN044 Nucleotide metabolism [c]: thymidine + ATP --> ADP + dTMP + H+
M116 R117 I R01569 5'-nucleotidase NT5 3.1.3.5 ? Nucleotide metabolism [c]: H2O + dTMP --> thymidine + orthophosphate
M117 R118 R R02094 thymidylate kinase TMPK 2.7.4.9 MPN006 Nucleotide metabolism [c]: dTMP + ATP <==> ADP + dTDP
M118 R119 I R02320 pyruvate kinase PYK 2.7.1.40 MPN303 Nucleotide metabolism [c]: phosphoenolpyruvate + dTDP + H+ --> dTTP + pyruvate
M119 R121/R122 I R00552 arginine deiminase ArcA 3.5.3.6 MPN304/MPN305;MPN560 Amino acid metabolism [c]: L-arginine + H2O --> NH3 + L-citrulline + H+
M120 R123 R R01398 ornithine carbamoyltransferase OTC 2.1.3.3 MPN306 Amino acid metabolism [c]: carbamoyl phosphate + L-ornithine <==> orthophosphate + H+ + L-citrulline
M121 R124 R R00150 carbamate kinase Ckase 2.7.2.2 MPN307 Amino acid metabolism [c]: CO2 + NH3 + ATP <==> ADP + carbamoyl phosphate + H+
M122 R125/R194 R R02235 dihydrofolate reductase DHFR 1.5.1.3 MPN321;MPN300 One carbon pool by folate [c]: NAD+ + dihydrofolate <==> NADH + folic acid
M123 R126/R195 R R00936 dihydrofolate reductase DHFR 1.5.1.3 MPN321;MPN300 One carbon pool by folate [c]: tetrahydrofolate + NAD+ <==> NADH + dihydrofolate + H+
M124 R127 I R00943 formate tetrahydrofolate ligase FHS 6.3.4.3 MPN017 One carbon pool by folate [c]: tetrahydrofolate + ATP + formate --> ADP + orthophosphate + 10-formyltetrahydrofolate
M125 R128 R R01655 methenyltetrahydrofolate cyclohydrolase MTHFC 3.5.4.9 MPN017 One carbon pool by folate [c]: H2O + 5,10-methenyltetrahydrofolate <==> 10-formyltetrahydrofolate
M126 R129 I R03940 methionyl-tRNA formyltransferase MTFMT 2.1.2.9 MPN543 One carbon pool by folate [c]: L-methionyl-tRNA(Met) + 10-formyltetrahydrofolate --> tetrahydrofolate + N-formylmethionyl-tRNA(Met)
M127 R130 R R00945 glycine hydroxymethyltransferase SHMT 2.1.2.1 MPN576 One carbon pool by folate [c]: glycine + H2O + 5,10-methylenetetrahydrofolate <==> tetrahydrofolate + L-serine
M128 R131 R R01220 methylenetetrahydrofolate dehydrogenase MTHFD 1.5.1.5 MPN017 One carbon pool by folate [c]: NADP+ + 5,10-methylenetetrahydrofolate <==> H+ + 5,10-methenyltetrahydrofolate + NADPH
M129 R132 I R02301 5-formyltetrahydrofolate cyclo-ligase MTHFS 6.3.3.2 MPN348 One carbon pool by folate [c]: ATP + 5-formyltetrahydrofolate --> ADP + orthophosphate + (2) H+ + 5,10-methenyltetrahydrofolate
M130 R185 I R02300? methenyltetrahydrofolate hydrolase? MTHFH ? MPN576 One carbon pool by folate [c]: H2O + H+ + 5,10-methenyltetrahydrofolate --> 5-formyltetrahydrofolate
M131 R181 R R11519 formate dehydrogenase FDH 1.2.1.2 ? One carbon pool by folate [c]: NAD+ + formate <==> CO2 + NADH
M132 R133 I R00177 methionine adenosyltransferase MAT 2.5.1.6 MPN060 Amino acid metabolism [c]: H2O + ATP + L-methionine --> orthophosphate + pyrophosphate + S-adenosyl-L-methionine
M133 R134 I R04858 DNA (cytosine-5-)-methyltransferase DCM 2.1.1.37 MPN108 Amino acid metabolism [c]: DNA (Mpn) + S-adenosyl-L-methionine --> 5mcDNA (Mpn) + S-adenosyl-L-homocysteine
M134 R135 I R00192 adenosylhomocysteinase AHC 3.3.1.1 ? Amino acid metabolism [c]: H2O + S-adenosyl-L-homocysteine --> L-homocysteine + adenosine
M135 R136 R R01724 nicotinate phosphoribosyltransferase PNCB 2.4.2.12 MPN047 Cofactor metabolism [c]: nicotinate D-ribonucleotide + pyrophosphate <==> nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + H+
M136 R137 R R03005 nicotinamide-nucleotide adenylyltransferase NADD 2.7.7.18 MPN336 Cofactor metabolism [c]: nicotinate D-ribonucleotide + H+ + ATP <==> deamino-NAD+ + pyrophosphate
M137 R138 I R00189 NAD+ synthase NADE 6.3.1.5 MPN562 Cofactor metabolism [c]: deamino-NAD+ + NH3 + ATP --> AMP + NAD+ + pyrophosphate
M138 R139 I R00104 NAD+ kinase NADK 2.7.1.23 MPN267 Cofactor metabolism [c]: NAD+ + ATP --> ADP + NADP+ + H+
M139 R173 I R00105 NAD+ kinase NADK 2.7.1.23 MPN267 Cofactor metabolism [c]: NADH + ATP --> ADP + H+ + NADPH
M140 R140 I R00549 riboflavin kinase RFK 2.7.1.26 MPN158 Cofactor metabolism [c]: riboflavin + ATP --> ADP + FMN + H+
M141 R141 I R00161 FAD synthetase FAD 2.7.7.2 MPN158 Cofactor metabolism [c]: FMN + H+ + ATP --> pyrophosphate + FAD
M142 R142 I R00174 pyridoxal kinase PDXK 2.7.1.35 ? Cofactor metabolism [c]: pyridoxal + ATP --> ADP + pyridoxal phosphate + H+
M143 R143 I R02134 thiamine kinase THIK 2.7.1.89 ? Cofactor metabolism [c]: ATP + thiamin --> ADP + H+ + thiamin monophosphate
M144 R144 I R00617 thiamine-phosphate kinase THIL 2.7.4.16 MPN550 Cofactor metabolism [c]: thiamin monophosphate + ATP --> ADP + thiamin diphosphate
M145 R145 I R02971 pantothenate kinase PANK 2.7.1.33 ? CoA metabolism [c]: pantetheine + ATP --> ADP + H+ + pantetheine 4-phosphate
M146 R146 I R03035 pantetheine-phosphate adenylyltransferase COASY 2.7.7.3 MPN336 CoA metabolism [c]: H+ + ATP + pantetheine 4-phosphate --> pyrophosphate + dephospho-CoA
M147 R147 I R00130 dephospho-CoA kinase COAE 2.7.1.24 MPN382 CoA metabolism [c]: ATP + dephospho-CoA --> ADP + CoA + H+
M148 R148 I R01625 holo-[acyl-carrier-protein] synthase ACPS 2.7.8.7 MPN298 CoA metabolism [c]: apoprotein [acyl carrier protein] + CoA --> adenosine 3',5'-bisphosphate + acyl carrier protein + H+
M149 R149 I R01623 [acyl-carrier-protein] phosphodiesterase ACPH 3.1.4.14 MPN479 CoA metabolism [c]: H2O + acyl carrier protein --> apoprotein [acyl carrier protein] + H+ + pantetheine 4-phosphate
M150 R188 I R00188 3'(2'),5'-bisphosphate nucleotidase BPNT 3.1.3.7 ? CoA metabolism [c]: H2O + adenosine 3',5'-bisphosphate --> AMP + orthophosphate
M151 R150 I R07325 long-chain-fatty-acid [acyl-carrier-protein] ligase AAS 6.2.1.20 ? CoA metabolism [c]: fatty acid (Mpn) + acyl carrier protein + ATP --> ACP-R (Mpn) + AMP + H+ + pyrophosphate
M152 R151 I R03905 glutaminyl-tRNA synthase GAT 6.3.5.7 MPN236-MPN238 Amino acid metabolism [c]: H2O + L-glutamyl-tRNA(Gln) + L-asparagine + ATP --> L-glutaminyl-tRNA(Gln) + ADP + orthophosphate + H+ + L-aspartate
M153 R152 I R03905 glutaminyl-tRNA synthase GAT 6.3.5.7 MPN236-MPN238 Amino acid metabolism [c]: L-glutamine + H2O + L-glutamyl-tRNA(Gln) + ATP --> L-glutaminyl-tRNA(Gln) + ADP + L-glutamate + orthophosphate + H+
M154 R153 I R03659 methionyl-tRNA synthetase METS 6.1.1.10 MPN023 Amino acid metabolism [c]: tRNA(Met) + L-methionine + ATP --> L-methionyl-tRNA(Met) + AMP + pyrophosphate
M155 R154 I R03656 isoleucyl-tRNA synthetase ILES 6.1.1.5 MPN520 Amino acid metabolism [c]: tRNA(Ile) + L-isoleucine + ATP --> L-isoleucyl-tRNA(Ile) + AMP + pyrophosphate
M156 R155 I R03665 valyl-tRNA synthetase VALS 6.1.1.9 MPN480 Amino acid metabolism [c]: tRNA(Val) + L-valine + ATP --> L-valyl-tRNA(Val) + AMP + pyrophosphate
M157 R156 I R03657 leucyl-tRNA synthetase LEUS 6.1.1.4 MPN384 Amino acid metabolism [c]: tRNA(Leu) + L-leucine + ATP --> AMP + L-leucyl-tRNA(Leu) + pyrophosphate
M158 R157 I R03650 cysteinyl-tRNA synthetase CYSS 6.1.1.16 MPN356 Amino acid metabolism [c]: tRNA(Cys) + ATP + L-cysteine --> AMP + pyrophosphate + L-cysteinyl-tRNA(Cys)
M159 R158 I R05578 glutamyl-tRNA synthetase GLTX 6.1.1.17 MPN678 Amino acid metabolism [c]: tRNA(Glu) + L-glutamate + ATP --> L-glutamyl-tRNA(Glu) + AMP + pyrophosphate
M160 R159 I R03651 glutamyl-tRNA synthetase GLTX 6.1.1.17 MPN678 Amino acid metabolism [c]: L-glutamate + ATP + tRNA(Gln) --> L-glutamyl-tRNA(Gln) + AMP + pyrophosphate
M161 R160 I R03646 arginyl-tRNA synthetase ARGS 6.1.1.19 MPN556 Amino acid metabolism [c]: L-arginine + tRNA(Arg) + ATP --> AMP + L-arginyl-tRNA(Arg) + pyrophosphate
M162 R161 I R02918 tyrosyl-tRNA synthetase TYRS 6.1.1.1 MPN669 Amino acid metabolism [c]: L-tyrosine + tRNA(Tyr) + ATP --> AMP + L-tyrosyl-tRNA(Tyr) + pyrophosphate
M163 R162 I R03664 tryptophanyl-tRNA synthetase TRPS 6.1.1.2 MPN265 Amino acid metabolism [c]: tRNA(Trp) + L-tryptophan + ATP --> AMP + L-tryptophanyl-tRNA(Trp) + pyrophosphate
M164 R163 I R03662 seryl-tRNA synthetase SERS 6.1.1.11 MPN005 Amino acid metabolism [c]: tRNA(Ser) + L-serine + ATP --> L-seryl-tRNA(Ser) + AMP + pyrophosphate
M165 R164 I R03663 threonyl-tRNA synthetase THRS 6.1.1.3 MPN553 Amino acid metabolism [c]: L-threonine + tRNA(Thr) + ATP --> AMP + L-threonyl-tRNA(Thr) + pyrophosphate
M166 R165 I R03661 prolyl-tRNA synthetase PROS 6.1.1.15 MPN402 Amino acid metabolism [c]: tRNA(Pro) + ATP + L-proline --> L-prolyl-tRNA(Pro) + AMP + pyrophosphate
M167 R166 I R05577 aspartyl-tRNA synthetase ASPS 6.1.1.12 MPN046 Amino acid metabolism [c]: tRNA(Asp) + L-aspartate + ATP --> AMP + L-aspartyl-tRNA(Asp) + pyrophosphate
M168 R167 I R03648 asparaginyl-tRNA synthetase ASNS 6.1.1.22 MPN252 Amino acid metabolism [c]: tRNA(Asn) + L-asparagine + ATP --> AMP + L-asparaginyl-tRNA(Asn) + pyrophosphate
M169 R168 I R03658 lysyl-tRNA synthetase LYSS 6.1.1.6 MPN277 Amino acid metabolism [c]: tRNA(Lys) + L-lysine + ATP --> AMP + pyrophosphate + L-lysyl-tRNA(Lys)
M170 R169 I R03655 histidyl-tRNA synthetase HISS 6.1.1.21 MPN045 Amino acid metabolism [c]: L-histidine + ATP + tRNA(His) --> AMP + L-histidyl-tRNA(His) + pyrophosphate
M171 R170 I R03660 phenylalanyl-tRNA synthetase PHES 6.1.1.20 MPN105/MPN106 Amino acid metabolism [c]: tRNA(Phe) + L-phenylalanine + ATP --> AMP + L-phenylalanyl-tRNA(Phe) + pyrophosphate
M172 R171 I R03038 alanyl-tRNA synthetase ALAS 6.1.1.7 MPN418 Amino acid metabolism [c]: L-alanine + tRNA(Ala) + ATP --> L-alanyl-tRNA(Ala) + AMP + pyrophosphate
M173 R172 I R03654 glycyl-tRNA synthetase GLYS 6.1.1.14 MPN354 Amino acid metabolism [c]: glycine + tRNA(Gly) + ATP --> glycyl-tRNA(Gly) + AMP + pyrophosphate
M174 - I - - - - - Nucleotide metabolism [c]: (100) H2O + RNA (Mpn) --> (28) GMP + (29) AMP + (18) CMP + (25) UMP + (100) H+
M175 - R - - - - ? Cofactor metabolism CO2[e] <==> CO2[c]
M176 - R - - - - ? Nucleotide metabolism uracil[e] + H+[e] <==> uracil[c] + H+[c]
M177 - I - - - - ? Nucleotide metabolism thymine[e] + H+[e] --> thymine[c] + H+[c]
M178 - I - - - - ? Pyruvate metabolism (S)-lactate[c] + H+[c] --> (S)-lactate[e] + H+[e]
M179 - R - - - - ? Cofactor metabolism oxygen[e] <==> oxygen[c]
M180 - I - - - - ? Cofactor metabolism riboflavin[e] --> riboflavin[c]
M181 - R - - - - ? Nucleotide metabolism cytidine[e] + H+[e] <==> cytidine[c] + H+[c]
M182 - I - - - - ? Amino acid metabolism L-homocysteine[c] --> L-homocysteine[e]
M183 - I - - - - ? Nucleotide metabolism guanine[e] + H+[e] --> guanine[c] + H+[c]
M184 - R - - - - ? Cofactor metabolism H2O2[e] <==> H2O2[c]
M185 - I - - - - ? Cofactor metabolism pyridoxal[e] --> pyridoxal[c]
M186 - I - - - - ? One carbon pool by folate folic acid[e] --> folic acid[c]
M187 - R - - - - ? CoA metabolism fatty acid (Mpn)[e] <==> fatty acid (Mpn)[c]
M188 - R - - - - ? Cofactor metabolism H2O[e] <==> H2O[c]
M189 - R - - - - ? Nucleotide metabolism adenine[c] + H+[c] <==> adenine[e] + H+[e]
M190 - I - - - - ? Cofactor metabolism nicotinate[e] --> nicotinate[c]
M191 - I - - - - ? CoA metabolism pantetheine[e] --> pantetheine[c]
M192 - I - - - - ? One carbon pool by folate L-serine[e] + H2O[c] + ATP[c] --> ADP[c] + L-serine[c] + orthophosphate[c] + H+[c]
M193 - I - - - - ? Amino acid metabolism L-methionine[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + L-methionine[c] + H+[c]
M194 - R - - - - ? Cofactor metabolism NH3[c] <==> NH3[e]
M195 - I - - - - ? Cofactor metabolism thiamin[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + H+[c] + thiamin[c]
M196 - R - - - - ? Lipid metabolism H+[e] + choline[e] <==> H+[c] + choline[c]
M197 - R - - - - ? Amino acid metabolism L-arginine[e] + L-ornithine[c] <==> L-ornithine[e] + L-arginine[c]
M198 - I - - - - ? Pyruvate metabolism H+[c] + acetate[c] --> H+[e] + acetate[e]
M199 - I - - - - ? Lipid metabolism phosphatidylcholine[e] + ATP[c] + H2O[c] --> phosphatidylcholine[c] + ADP[c] + orthophosphate[c] + H+[c]
M200 - I - - - - ? Amino acid metabolism L-alanine[c] + H+[c] --> L-alanine[e] + H+[e]
M201 - I - - - - ? Amino acid metabolism L-arginine[c] + H+[c] --> L-arginine[e] + H+[e]
M202 - I - - - - ? Amino acid metabolism L-asparagine[c] + H+[c] --> L-asparagine[e] + H+[e]
M203 - I - - - - ? Amino acid metabolism H+[c] + L-aspartate[c] --> H+[e] + L-aspartate[e]
M204 - I - - - - ? Amino acid metabolism H+[c] + L-cysteine[c] --> H+[e] + L-cysteine[e]
M205 - I - - - - ? Amino acid metabolism L-glutamate[c] + H+[c] --> L-glutamate[e] + H+[e]
M206 - I - - - - ? Amino acid metabolism L-glutamine[c] + H+[c] --> L-glutamine[e] + H+[e]
M207 - I - - - - ? Amino acid metabolism glycine[c] + H+[c] --> glycine[e] + H+[e]
M208 - I - - - - ? Amino acid metabolism L-histidine[c] + H+[c] --> L-histidine[e] + H+[e]
M209 - I - - - - ? Amino acid metabolism L-isoleucine[c] + H+[c] --> L-isoleucine[e] + H+[e]
M210 - I - - - - ? Amino acid metabolism L-leucine[c] + H+[c] --> H+[e] + L-leucine[e]
M211 - I - - - - ? Amino acid metabolism L-lysine[c] + H+[c] --> L-lysine[e] + H+[e]
M212 - I - - - - ? Amino acid metabolism H+[c] + L-methionine[c] --> H+[e] + L-methionine[e]
M213 - I - - - - ? Amino acid metabolism L-phenylalanine[c] + H+[c] --> L-phenylalanine[e] + H+[e]
M214 - I - - - - ? Amino acid metabolism H+[c] + L-proline[c] --> H+[e] + L-proline[e]
M215 - I - - - - ? Amino acid metabolism L-serine[c] + H+[c] --> L-serine[e] + H+[e]
M216 - I - - - - ? Amino acid metabolism L-threonine[c] + H+[c] --> L-threonine[e] + H+[e]
M217 - I - - - - ? Amino acid metabolism L-tryptophan[c] + H+[c] --> L-tryptophan[e] + H+[e]
M218 - I - - - - ? Amino acid metabolism L-tyrosine[c] + H+[c] --> L-tyrosine[e] + H+[e]
M219 - I - - - - ? Amino acid metabolism L-valine[c] + H+[c] --> L-valine[e] + H+[e]
M220 - I - - - - ? Nucleotide metabolism deoxycytidine[e] + H+[e] --> deoxycytidine[c] + H+[c]
M221 - I - - - - ? Amino acid metabolism L-arginine[e] + H2O[c] + ATP[c] --> ADP[c] + L-arginine[c] + orthophosphate[c] + H+[c]
M222 - I - - - - ? Amino acid metabolism L-aspartate[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + H+[c] + L-aspartate[c]
M223 - I - - - - ? Amino acid metabolism L-cysteine[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + H+[c] + L-cysteine[c]
M224 - I - - - - ? Amino acid metabolism L-glutamate[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + L-glutamate[c] + H+[c]
M225 - I - - - - ? Amino acid metabolism glycine[e] + H2O[c] + ATP[c] --> ADP[c] + glycine[c] + orthophosphate[c] + H+[c]
M226 - I - - - - ? Amino acid metabolism L-isoleucine[e] + H2O[c] + ATP[c] --> ADP[c] + L-isoleucine[c] + orthophosphate[c] + H+[c]
M227 - I - - - - ? Amino acid metabolism L-alanine[e] + H2O[c] + ATP[c] --> L-alanine[c] + ADP[c] + orthophosphate[c] + H+[c]
M228 - I - - - - ? Amino acid metabolism L-asparagine[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + L-asparagine[c] + H+[c]
M229 - I - - - - ? Amino acid metabolism L-leucine[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + L-leucine[c] + H+[c]
M230 - I - - - - ? Amino acid metabolism L-glutamine[e] + H2O[c] + ATP[c] --> L-glutamine[c] + ADP[c] + orthophosphate[c] + H+[c]
M231 - I - - - - ? Amino acid metabolism L-histidine[e] + H2O[c] + ATP[c] --> ADP[c] + L-histidine[c] + orthophosphate[c] + H+[c]
M232 - I - - - - ? Amino acid metabolism L-lysine[e] + H2O[c] + ATP[c] --> ADP[c] + L-lysine[c] + orthophosphate[c] + H+[c]
M233 - I - - - - ? Amino acid metabolism L-proline[e] + H2O[c] + ATP[c] --> ADP[c] + orthophosphate[c] + H+[c] + L-proline[c]
M234 - I - - - - ? Amino acid metabolism L-phenylalanine[e] + H2O[c] + ATP[c] --> ADP[c] + L-phenylalanine[c] + orthophosphate[c] + H+[c]
M235 - I - - - - ? Amino acid metabolism L-threonine[e] + H2O[c] + ATP[c] --> ADP[c] + L-threonine[c] + orthophosphate[c] + H+[c]
M236 - I - - - - ? Amino acid metabolism L-tryptophan[e] + H2O[c] + ATP[c] --> ADP[c] + L-tryptophan[c] + orthophosphate[c] + H+[c]
M237 - I - - - - ? Amino acid metabolism L-tyrosine[e] + H2O[c] + ATP[c] --> ADP[c] + L-tyrosine[c] + orthophosphate[c] + H+[c]
M238 - I - - - - ? Amino acid metabolism L-valine[e] + H2O[c] + ATP[c] --> ADP[c] + L-valine[c] + orthophosphate[c] + H+[c]
M239 - I - - - - MPN609-MPN611 Cofactor metabolism orthophosphate[e] + H2O[c] + ATP[c] --> ADP[c] + (2) orthophosphate[c] + H+[c]
M240 - I - - - - ? Cofactor metabolism orthophosphate[c] --> orthophosphate[e]
M241 - I - - - - - sink/source [e]: (S)-lactate -->
M242 - I - - - - - sink/source [c]: 5mcDNA (Mpn) -->
M243 - I - - - - - sink/source [e]: acetate -->
M244 - R - - - - - sink/source [e]: adenine <==>
M245 - I - - - - - sink/source [c]: adenosine 3',5'-bisphosphate -->
M246 - R - - - - - sink/source [e]: biomass -->
M247 - R - - - - - sink/source [e]: CO2 <==>
M248 - R - - - - - sink/source [e]: glycine <==>
M249 - I - - - - - sink/source [e]: H2O2 -->
M250 - R - - - - - sink/source [e]: L-alanine <==>
M251 - R - - - - - sink/source [e]: L-arginine <==>
M252 - R - - - - - sink/source [e]: L-asparagine <==>
M253 - R - - - - - sink/source [e]: L-aspartate <==>
M254 - R - - - - - sink/source [e]: L-cysteine <==>
M255 - R - - - - - sink/source [e]: L-glutamate <==>
M256 - R - - - - - sink/source [e]: L-glutamine <==>
M257 - R - - - - - sink/source [e]: L-histidine <==>
M258 - I - - - - - sink/source [e]: L-homocysteine -->
M259 - R - - - - - sink/source [e]: L-isoleucine <==>
M260 - R - - - - - sink/source [e]: L-leucine <==>
M261 - R - - - - - sink/source [e]: L-lysine <==>
M262 - R - - - - - sink/source [e]: L-methionine <==>
M263 - I - - - - - sink/source [e]: L-ornithine -->
M264 - R - - - - - sink/source [e]: L-phenylalanine <==>
M265 - R - - - - - sink/source [e]: L-proline <==>
M266 - R - - - - - sink/source [e]: L-serine <==>
M267 - R - - - - - sink/source [e]: L-threonine <==>
M268 - R - - - - - sink/source [e]: L-tryptophan <==>
M269 - R - - - - - sink/source [e]: L-tyrosine <==>
M270 - R - - - - - sink/source [e]: L-valine <==>
M271 - I - - - - - sink/source [c]: NADP+ -->
M272 - R - - - - - sink/source [e]: NH3 <==>
M273 - I - - - - - sink/source [e]: --> ascorbate
M274 - R - - - - - sink/source [e]: <==> choline
M275 - I - - - - - sink/source [e]: --> cytidine
M276 - I - - - - - sink/source [e]: --> deoxycytidine
M277 - I - - - - - sink/source [e]: --> D-fructose
M278 - I - - - - - sink/source [e]: --> D-mannose
M279 - I - - - - - sink/source [e]: --> D-ribose
M280 - R - - - - - sink/source [e]: <==> fatty acid (Mpn)
M281 - I - - - - - sink/source [e]: --> folic acid
M282 - I - - - - - sink/source [e]: --> D-glucose
M283 - I - - - - - sink/source [e]: --> glycerol
M284 - I - - - - - sink/source [e]: --> guanine
M285 - R - - - - - sink/source [e]: <==> H+
M286 - I - - - - - sink/source [e]: --> mannitol
M287 - I - - - - - sink/source [e]: --> nicotinate
M288 - R - - - - - sink/source [e]: <==> orthophosphate
M289 - I - - - - - sink/source [e]: --> oxygen
M290 - I - - - - - sink/source [e]: --> pantetheine
M291 - I - - - - - sink/source [e]: --> phosphatidylcholine
M292 - I - - - - - sink/source [e]: --> pyridoxal
M293 - I - - - - - sink/source [e]: --> riboflavin
M294 - I - - - - - sink/source [e]: --> sn-glycerol 3-phosphate
M295 - I - - - - - sink/source [e]: --> thiamin
M296 - I - - - - - sink/source [e]: --> thymine
M297 - I - - - - - sink/source [e]: --> uracil
M298 - R - - - - - sink/source [e]: <==> H2O
M299 - I - - - - - Protein metabolism [c]: (25) L-valyl-tRNA(Val) + (18) L-aspartyl-tRNA(Asp) + (13) L-arginyl-tRNA(Arg) + N-formylmethionyl-tRNA(Met) + (826) ATP + (32) L-lysyl-tRNA(Lys) + (17) L-glutaminyl-tRNA(Gln) + (22) L-isoleucyl-tRNA(Ile) + (482) H2O + (21) L-seryl-tRNA(Ser) + (14) L-prolyl-tRNA(Pro) + (21) glycyl-tRNA(Gly) + (2
M300 - I - DnaK chaperone DnaK 3.6.3.51 MPN434/MPN002/MPN120 Protein metabolism [c]: H2O + protein (Mpn) + ATP --> ADP + orthophosphate + DnaK-folded protein (Mpn) + H+
M301 - I - Chaperonin GroEL GroEL 3.6.4.9 MPN573/MPN574 Protein metabolism [c]: (7) H2O + protein (Mpn) + (7) ATP --> (7) ADP + GroEL-folded protein (Mpn) + (7) orthophosphate + (7) H+
M302 - I - - - - - Protein metabolism [c]: (1032) H2O + protein (Mpn) + (688) ATP --> (27) L-alanine + (10) L-tyrosine + (21) glycine + (3) L-tryptophan + (21) L-serine + (20) L-asparagine + (22) L-glutamate + (29) L-leucine + (688) H+ + (14) L-proline + (3) L-cysteine + (13) L-arginine + (32) L-lysine + (21) L-threonine + (15) L-phenyl
M303 - I - - - - - Protein metabolism [c]: (5) L-valyl-tRNA(Val) + (6) L-aspartyl-tRNA(Asp) + (2) L-arginyl-tRNA(Arg) + N-formylmethionyl-tRNA(Met) + (199) ATP + (11) L-lysyl-tRNA(Lys) + (4) L-glutaminyl-tRNA(Gln) + (8) L-isoleucyl-tRNA(Ile) + (199) H2O + (5) L-seryl-tRNA(Ser) + L-prolyl-tRNA(Pro) + glycyl-tRNA(Gly) + (4) L-alanyl-tRNA(
M304 - I - - - - - Energy metabolism [c]: H2O + ATP --> ADP + orthophosphate + H+
M305 - I - - - - - Biomass production [c]: (1657) guanosine + (1366) L-tyrosine + (9220) glycine + (1864) L-tryptophan + (54) L-asparagine + (100) S-adenosyl-L-methionine + (100) pyridoxal phosphate + (67) L-cysteine + (100) thiamin diphosphate + (2489) L-threonine + (100) 5-formyltetrahydrofolate + (1242) thymidine + (2793) L-valine +
M306 - I - - - - - Biomass production biomass[c] + (25) H2O[c] + (25) ATP[c] --> biomass[e] + (25) ADP[c] + (25) orthophosphate[c] + (25) H+[c]
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