Table S9: Predicted Fluxes for the Exponential Growth Phase reaction ID 24h 36h 48h 60h M001 5.10836 7.369 9.69714 12.3776 M002 5.0835 7.34078 9.67749 12.3683 M003 5.16243 7.45648 9.8343 12.5723 M004 5.16243 7.45648 9.8343 12.5723 M005 -5.40839 -7.81419 -10.3117 -13.1877 M006 10.6103 15.3285 20.2244 25.862 M007 -10.6103 -15.3285 -20.2244 -25.862 M008 -10.6103 -15.3285 -20.2244 -25.862 M009 10.6103 15.3285 20.2244 25.862 M010 4.9216 7.37505 9.95335 12.9233 M011 -3.16668 -8.39742 -15.6053 -23.1843 M012 7.4436 6.9311 4.6191 2.6777 M013 -7.4436 -6.9311 -4.6191 -2.6777 M014 7.4436 6.9311 4.6191 2.6777 M015 7.4436 6.9311 4.6191 2.6777 M016 -7.4436 -6.9311 -4.6191 -2.6777 M017 7.44291 6.93027 4.61863 2.67759 M018 0.0922169 0.100645 0.0791637 0.0533939 M019 0 0 0 0 M020 0 0 0 0 M021 0 0 0 0 M022 0 0 0 0 M023 0 0 0 0 M024 0 0 0 0 M025 0 0 0 0 M026 0 0 0 0 M027 0 0 0 0 M028 0 0 0 0 M029 0 0 0 0 M030 0 0 0 0 M031 0 0 0 0 M032 0.127709 0.184225 0.242428 0.30944 M033 0.127709 0.184225 0.242428 0.30944 M034 -0.0394621 -0.0578489 -0.0784016 -0.102028 M035 0.0394621 0.0578489 0.0784016 0.102028 M036 -0.0394621 -0.0578489 -0.0784016 -0.102028 M037 0.0789242 0.115698 0.156803 0.204056 M038 0.0789242 0.115698 0.156803 0.204056 M039 0 0 0 0 M040 -0.00932266 -0.0106783 -0.00722312 -0.00335526 M041 0 0 0 0 M042 0 0 0 0 M043 0 0 0 0 M044 -0.127709 -0.184225 -0.242428 -0.30944 M045 0.127709 0.184225 0.242428 0.30944 M046 0.127709 0.184225 0.242428 0.30944 M047 0.245959 0.357712 0.477379 0.615333 M048 0.01 0.01 0.01 0.01 M049 0.01 0.01 0.01 0.01 M050 0.00945854 0.0107382 0.00747673 0.00354742 M051 0.00945854 0.0107382 0.00747673 0.00354742 M052 0 0 0 0 M053 0 0 0 0 M054 0 0 0 0 M055 0 0 0 0 M056 0.00284386 0.0032286 0.00224799 0.00106659 M057 -0.0170631 -0.0193716 -0.013488 -0.00639952 M058 0.0170631 0.0193716 0.013488 0.00639952 M059 0.00853157 0.00968581 0.00674398 0.00319976 M060 0.00284386 0.0032286 0.00224799 0.00106659 M061 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M062 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M063 0 0 0 0 M064 0 0 0 0 M065 -0.00281929 -0.00468143 -0.00315359 -0.00146034 M066 -8.84E-05 -0.000100403 -6.99E-05 -3.32E-05 M067 0 0 0 0 M068 0.613989 0.651928 0.558451 0.446129 M069 0 0.00143352 0.000998121 0.00047357 M070 0.00126269 0.00143352 0.000998121 0.000621014 M071 0.00783096 0.00784313 0.00781211 0.00777474 M072 1.1943 1.23496 1.13134 1.00678 M073 -0.00217501 -0.00103576 -0.000721171 -0.000342168 M074 0.00217501 0.00103576 0.000721171 0.000342168 M075 0.00217501 0.00103576 0.000721171 0.000342168 M076 0.00217501 0.00246927 0.00171929 0.000815738 M077 0 0 0 0 M078 7.25E-05 8.23E-05 5.73E-05 2.72E-05 M079 -0.00378145 -0.00285953 -0.00199102 -0.000944662 M080 -7.40E-05 -8.40E-05 -5.85E-05 -2.77E-05 M081 0 0 0 0 M082 0.220529 0.219608 0.218739 0.217693 M083 0.00126269 0 0 0 M084 0.219267 0.219608 0.218739 0.217693 M085 0 0 0 0 M086 -0.000187323 -0.00164618 -0.00114619 -0.000543825 M087 0.000187323 0.00164618 0.00114619 0.000543825 M088 0.000187323 0.00164618 0.00114619 0.000543825 M089 0.00145001 0.00164618 0.00114619 0.000543825 M090 0 0 0 0 M091 0.00679791 0.00781201 0.00522737 0.00240835 M092 -0.00916025 -0.010494 -0.00709473 -0.00329435 M093 0 0 0 0 M094 0.00904681 0.0103652 0.00700506 0.0032518 M095 0.195774 0.196078 0.195303 0.194368 M096 0.212837 0.21545 0.208791 0.200768 M097 0 0 0 0 M098 0 0 0 0 M099 0.00162367 0.00184334 0.00128347 0.000756401 M100 0 0 0 0 M101 0.140962 0.141181 0.140621 0.140094 M102 0.140962 0.141181 0.140621 0.139947 M103 0 0 0 0.000147444 M104 0.00145001 0.00164618 0.00114619 0.000396382 M105 0 0 0 0 M106 0.00145001 0.00164618 0.00114619 0.000396382 M107 0.00145001 0.00164618 0.00114619 0.000543825 M108 0.00459279 0.00521416 0.00363049 0.00172253 M109 0.00236234 0.00268194 0.00186737 0.000885993 M110 0.00223046 0.00253222 0.00176312 0.000836533 M111 0 0 0 0 M112 0 0 0 0 M113 0.00223046 0.00253222 0.00176312 0.000836533 M114 0 0 0 0 M115 0 0 0 0 M116 5.54E-05 6.29E-05 4.38E-05 2.08E-05 M117 0.00217501 0.00246927 0.00171929 0.000815738 M118 0.00217501 0.00246927 0.00171929 0.000815738 M119 0.240511 0.239227 0.242499 0.246441 M120 -0.240511 -0.239227 -0.242499 -0.246441 M121 -0.240511 -0.239227 -0.242499 -0.246441 M122 -4.46E-06 -5.07E-06 -3.53E-06 -1.67E-06 M123 -0.00223492 -0.00253729 -0.00176665 -0.000838208 M124 0 0 0 0 M125 0.00106551 0.00116246 0.000915358 0.000617665 M126 0.00106551 0.00116246 0.000915363 0.000617665 M127 -0.00330044 -0.00369975 -0.00268201 -0.00145587 M128 0.00106998 0.00116753 0.000918892 0.000619339 M129 0.00999554 0.00999493 0.00999647 0.00999833 M130 0.01 0.01 0.01 0.01 M131 0.00106538 0.00116231 0.000915257 0.000617615 M132 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M133 0 0 0 0 M134 0 0 0 0 M135 -0.000197175 -0.000271053 -8.28E-05 -3.35E-06 M136 0.000197175 0.000271053 8.28E-05 3.35E-06 M137 0.000197175 0.000271053 8.28E-05 3.35E-06 M138 0 0 0 0 M139 0.000197175 0.000271053 8.28E-05 3.35E-06 M140 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M141 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M142 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M143 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M144 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M145 4.60E-06 5.22E-06 3.63E-06 1.72E-06 M146 4.60E-06 5.22E-06 3.63E-06 1.72E-06 M147 4.60E-06 5.22E-06 3.63E-06 1.72E-06 M148 1.34E-07 1.52E-07 1.06E-07 5.02E-08 M149 0 0 0 0 M150 1.34E-07 1.52E-07 1.06E-07 5.02E-08 M151 0.0189171 0.0214764 0.0149535 0.00709484 M152 0 0 0 0 M153 0.018112 0.0197599 0.0155598 0.0104997 M154 0.0063928 0.00697447 0.00549196 0.00370589 M155 0.0234394 0.025572 0.0201365 0.0135879 M156 0.0266351 0.0290585 0.022882 0.0154406 M157 0.0308976 0.0337088 0.0265437 0.0179114 M158 0.00319613 0.00348693 0.00274577 0.00185284 M159 0.0234398 0.0255725 0.0201368 0.0135881 M160 0.018112 0.0197599 0.0155598 0.0104997 M161 0.0138502 0.0151103 0.0118986 0.00802909 M162 0.0106538 0.0116231 0.00915257 0.00617615 M163 0.00319613 0.00348693 0.00274577 0.00185284 M164 0.0223736 0.0244093 0.0192209 0.0129702 M165 0.0223731 0.0244087 0.0192205 0.01297 M166 0.0149154 0.0162725 0.0128137 0.00864666 M167 0.0191776 0.0209225 0.0164753 0.0111174 M168 0.0213079 0.0232467 0.0183055 0.0123524 M169 0.0340935 0.0371956 0.0292894 0.0197642 M170 0.0063924 0.00697401 0.00549165 0.00370574 M171 0.0159813 0.0174354 0.0137294 0.00926447 M172 0.0287657 0.031383 0.0247124 0.0166758 M173 0.0223731 0.0244087 0.0192205 0.01297 M174 0.007741 0.007741 0.007741 0.007741 M175 -7.68518 -7.17149 -4.86251 -2.92476 M176 0 0 0 0 M177 0 0 0 0 M178 3.16668 8.39742 15.6053 23.1843 M179 7.68887 7.28799 5.09601 3.29292 M180 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M181 0.00164613 0.00186883 0.00130122 0.000764823 M182 0 0 0 0 M183 0.00404275 0.00458969 0.00319569 0.00151623 M184 -0.245959 -0.357712 -0.477379 -0.615333 M185 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M186 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M187 0.0189171 0.0214764 0.0149535 0.00709484 M188 -7.53968 -7.05254 -4.47367 -2.21489 M189 0.00508274 0.00581759 0.00394467 0.00183568 M190 0.000197175 0.000271053 8.28E-05 3.35E-06 M191 4.60E-06 5.22E-06 3.63E-06 1.72E-06 M192 0.0184901 0.0209444 0.014689 0.00715274 M193 0.00436503 0.00495557 0.00345044 0.0016371 M194 0.485417 0.483397 0.488546 0.494601 M195 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M196 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M197 0.240511 0.239227 0.242499 0.246441 M198 7.4436 6.9311 4.6191 2.6777 M199 0 0 0 0 M200 0 0 0 0 M201 0 0 0 0 M202 0 0 0 0 M203 0 0 0 0 M204 0 0 0 0 M205 0 0 0 0 M206 0 0 0 0 M207 0 0 0 0 M208 0 0 0 0 M209 0 0 0 0 M210 0 0 0 0 M211 0 0 0 0 M212 0 0 0 0 M213 0 0 0 0 M214 0 0 0 0 M215 0 0 0 0 M216 0 0 0 0 M217 0 0 0 0 M218 0 0 0 0 M219 0 0 0 0 M220 0.0060428 0.00686034 0.00477668 0.00211891 M221 0.00948916 0.010773 0.00750094 0.00355891 M222 0.0133134 0.0151146 0.0105239 0.00499318 M223 0.00215242 0.00244363 0.00170144 0.000807266 M224 0.0165966 0.018842 0.0131192 0.00622456 M225 0.0121573 0.0138493 0.00953696 0.00434156 M226 0.0158465 0.0179904 0.0125263 0.00594323 M227 0.019784 0.0224606 0.0156387 0.00741998 M228 0.0143324 0.0162714 0.0113294 0.00537535 M229 0.0217309 0.0246709 0.0171777 0.00815018 M230 0.0121938 0.0138435 0.00963887 0.00457327 M231 0.00440712 0.00500337 0.00348372 0.00165289 M232 0.0230065 0.026119 0.018186 0.00862857 M233 0.010336 0.0117344 0.00817038 0.00387653 M234 0.0109765 0.0124615 0.00867663 0.00411673 M235 0.0151573 0.0172079 0.0119814 0.00568473 M236 0.00223265 0.0025347 0.00176485 0.000837354 M237 0.00722576 0.00820333 0.00571177 0.00271002 M238 0.0180373 0.0204776 0.014258 0.00676488 M239 0 0 0 0 M240 0.0945652 0.146456 0.216448 0.297221 M241 3.16668 8.39742 15.6053 23.1843 M242 0 0 0 0 M243 7.4436 6.9311 4.6191 2.6777 M244 -0.00508274 -0.00581759 -0.00394467 -0.00183568 M245 0 0 0 0 M246 0.0446431 0.0506829 0.0352892 0.0167434 M247 7.68518 7.17149 4.86251 2.92476 M248 -0.0121573 -0.0138493 -0.00953696 -0.00434156 M249 0.245959 0.357712 0.477379 0.615333 M250 -0.019784 -0.0224606 -0.0156387 -0.00741998 M251 -0.25 -0.25 -0.25 -0.25 M252 -0.0143324 -0.0162714 -0.0113294 -0.00537535 M253 -0.0133134 -0.0151146 -0.0105239 -0.00499318 M254 -0.00215242 -0.00244363 -0.00170144 -0.000807266 M255 -0.0165966 -0.018842 -0.0131192 -0.00622456 M256 -0.0121938 -0.0138435 -0.00963887 -0.00457327 M257 -0.00440712 -0.00500337 -0.00348372 -0.00165289 M258 0 0 0 0 M259 -0.0158465 -0.0179904 -0.0125263 -0.00594323 M260 -0.0217309 -0.0246709 -0.0171777 -0.00815018 M261 -0.0230065 -0.026119 -0.018186 -0.00862857 M262 -0.00436503 -0.00495557 -0.00345044 -0.0016371 M263 0.240511 0.239227 0.242499 0.246441 M264 -0.0109765 -0.0124615 -0.00867663 -0.00411673 M265 -0.010336 -0.0117344 -0.00817038 -0.00387653 M266 -0.0184901 -0.0209444 -0.014689 -0.00715274 M267 -0.0151573 -0.0172079 -0.0119814 -0.00568473 M268 -0.00223265 -0.0025347 -0.00176485 -0.000837354 M269 -0.00722576 -0.00820333 -0.00571177 -0.00271002 M270 -0.0180373 -0.0204776 -0.014258 -0.00676488 M271 0.000188246 0.000260917 7.57E-05 0 M272 0.485417 0.483397 0.488546 0.494601 M273 0 0 0 0 M274 -4.46E-06 -5.07E-06 -3.53E-06 -1.67E-06 M275 0.00164613 0.00186883 0.00130122 0.000764823 M276 0.0060428 0.00686034 0.00477668 0.00211891 M277 0 0 0 0 M278 0 0 0 0 M279 0.127709 0.184225 0.242428 0.30944 M280 0.0189171 0.0214764 0.0149535 0.00709484 M281 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M282 5.10836 7.369 9.69714 12.3776 M283 0.127709 0.184225 0.242428 0.30944 M284 0.00404275 0.00458969 0.00319569 0.00151623 M285 -10.2246 -14.9068 -19.8945 -25.6422 M286 0 0 0 0 M287 0.000197175 0.000271053 8.28E-05 3.35E-06 M288 0.0945652 0.146456 0.216448 0.297221 M289 7.68887 7.28799 5.09601 3.29292 M290 4.60E-06 5.22E-06 3.63E-06 1.72E-06 M291 0 0 0 0 M292 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M293 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M294 0.127709 0.184225 0.242428 0.30944 M295 4.46E-06 5.07E-06 3.53E-06 1.67E-06 M296 0 0 0 0 M297 0 0 0 0 M298 -7.53968 -7.05254 -4.47367 -2.21489 M299 0.00106538 0.00116231 0.000915257 0.000617615 M300 0 0 0 0 M301 0 0 0 0 M302 0.0003489 0.0003489 0.0003489 0.0003489 M303 1.34E-07 1.52E-07 1.06E-07 5.02E-08 M304 13.105 16.9618 20.435 25.2015 M305 4.46E-08 5.07E-08 3.53E-08 1.67E-08 M306 0.0446431 0.0506829 0.0352892 0.0167434 Table S9: Predicted Fluxes for the Exponential Growth Phase: The fluxes for all model reactions in mmol per gram of cells and hour as predicted for different time points of the exponential growth phase of batch culture growth are shown. Negative fluxes indicate that the flux direction of the respective reaction is opposed to the reaction annotation in table S1.