MyMpn Project

Name	ywfO
Stable ID	MPN677
Location	800735 - 802012 -
Sequence	1 ATGCAACAAA TCTTTTTTAA AGATCCCATT TTAGGGGAAG TGCTGTTTGA CCAACAAACT 61 AAGTGGATGT ATGAGTTGGT GGAAACGGAA GCGTTTCGCC GTTTACGTAA CATTAAGCAG 121 CTAGGAATTA ACTTTCATTT TTATCCGGGG GGCGTGCACA CGCGTTATTC CCACTCCTTG 181 GGGGTTTATG AACTGTTAAG GCGGATCTTA AACACCCCCG CGTTTGCTCC GATTGATGAA 241 AACAAAAAGC AAACGGTGTT AGTAGCGGGA TTACTGCACG ACATTGGTCA TGCACCGCAT 301 TCCCATGCCT TTGAGATTTA CTTTGCCAAA GCCCCTAACT TTAAGAAGGA GCTGTTTATC 361 CACGAAGAAG TTACAACCTT ATTTGTCAAC AGTGAACCGA TTAAATCAAT CTTAAAGGCG 421 AACCAGATTG ATCCTAAACT AGTAGCTGCT TTAATTGATG AAAACAAGGA GTTAAAGCCA 481 TCCAACTACT GGATGCGCCA GTTAATTTCA TCTGACTTGG ATGCTGACCG GATGGATTAC 541 CTGTTGCGCG ATTCCTACTT TACGGGTACC AGTCATTCCT TGATAGATTA CCAAACGATT 601 ATTAAGGAGA TGGACTGTGT CAAGGTCAAG GGGATTTACG AAATCTTCTT TAAGGATAAG 661 TGCTTGCCCT TAATTGAAAA CTTCTTAATT ACCCGGCACC ACATGTACCA ATCAATCTAC 721 AGCGATGGCA GGAGTATTTC CACCGAGTTA AACCTTTGGT TTGTCTTTCA ACGAATTAAG 781 GACTTAGTGG ACAAAAACCA GTTTGACTTC AACGGTTATA AAACCTTAGA ACAGGTGTGC 841 TTACCACTAC TCAAGAACGA ACACTTTGAC AAAAAGATGC TGCCAGCGTT TGTTAAGTTA 901 GATGACTATG TGTTCCAATC GTTCTTTGTT AACTTGTACC AAACCACCAA GGACAAGATC 961 TTAAAGAAGT TGTTGGACAG TTATTTAAAC AGTTTGAAGT TCGAAATTAA GTTTTACGAA 1021 ACCAAGGAAC AGAGGGACTT AGACTTTGAA AAACAGGCGA GCAAGTACAA GGATGCTAAG 1081 TACTTTATTA CGAAGTTTAA CAATCAGTTT AAGGGCTTTT ATGAGGGTTG AAGTAGTCAT 1141 AAGAATGAGC TCAAAATTAA AACTATGCAA AACAAGCACA CTAACCTCAG TGAAATCAGT 1201 ATGTTGGTAA AGCGTAGTAA TGAACTGTTC TTTGAAAATG CACTGTACAA GTGGGCTAAC 1261 GTTTTCTACC GCCTTTAA
Download Sequence
Operon	OP303
Operon location	800675 - 803732

MQQIFFKDPILGEVLFDQQTKWMYELVETEAFRRLRNIKQLGINFHFYPGGVHTRYSHSLGVYELLRRILNTPAFAPIDE

NKKQTVLVAGLLHDIGHAPHSHAFEIYFAKAPNFKKELFIHEEVTTLFVNSEPIKSILKANQIDPKLVAALIDENKELKP

SNYWMRQLISSDLDADRMDYLLRDSYFTGTSHSLIDYQTIIKEMDCVKVKGIYEIFFKDKCLPLIENFLITRHHMYQSIY

SDGRSISTELNLWFVFQRIKDLVDKNQFDFNGYKTLEQVCLPLLKNEHFDKKMLPAFVKLDDYVFQSFFVNLYQTTKDKI

LKKLLDSYLNSLKFEIKFYETKEQRDLDFEKQASKYKDAKYFITKFNNQFKGFYEGWSSHKNELKIKTMQNKHTNLSEIS

MLVKRSNELFFENALYKWANVFYRL

Name	DGT (deoxyguanosinetriphosphate triphosphohydrolase) (EC 3.1.5.1). Putative Transcription factor?.
Stable ID	Mpn677
Molecular Weight	46750
Isoelectric Point	9
Localization	Cytoplasm
Comment	DGT (deoxyguanosinetriphosphate triphosphohydrolase) (EC 3.1.5.1). new_similar to ATPases; Lin2710 protein; Lmo2565 protein; Similar to dGTP triphosphohydrolase; YwfO; This enzyme participates in purine metabolism. The native enzyme, purified from wild-type E. coli, is a tetramer (Seto et al., 1988) with a subunit molecular weight of 56,000-59,000. Degrades NTPs into bases and PPP, Could be related to RNA modification, or regulate levels of NTPs. Binds to single and double stranded DNA. Nucleotidil transferase?; Crystallized
Sequence	MQQIFFKDPILGEVLFDQQTKWMYELVETEAFRRLRNIKQLGINFHFYPGGVHTRYSHSLGVYELLRRILNTPAFAPIDE NKKQTVLVAGLLHDIGHAPHSHAFEIYFAKAPNFKKELFIHEEVTTLFVNSEPIKSILKANQIDPKLVAALIDENKELKP SNYWMRQLISSDLDADRMDYLLRDSYFTGTSHSLIDYQTIIKEMDCVKVKGIYEIFFKDKCLPLIENFLITRHHMYQSIY SDGRSISTELNLWFVFQRIKDLVDKNQFDFNGYKTLEQVCLPLLKNEHFDKKMLPAFVKLDDYVFQSFFVNLYQTTKDKI LKKLLDSYLNSLKFEIKFYETKEQRDLDFEKQASKYKDAKYFITKFNNQFKGFYEGWSSHKNELKIKTMQNKHTNLSEIS MLVKRSNELFFENALYKWANVFYRL

Modification	Modified sequence	Relative start	Relative end	Amino acid
Oxidation	mQQIFFKDPILGEVLFDQQTK	1	22	M
Oxidation	LVAALIDENKELKPSNYWmR	147	167	M
Oxidation	HTNLSEISmLVK	393	405	M

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
1-417	SSF109604 (n.a.)	NULL			0
2-267	G3DSA:1.10.3210.10 (n.a.)	NULL			0
6-352	PTHR11373:SF4 (n.a.)	NULL			0
6-352	PTHR11373 (n.a.)	NULL			0
51-190	SM00471 (IPR003607)	Metal-dependent phosphohydrolase, HD domain	Molecular Function: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003824'>'catalytic' == '' ? '': 'catalytic'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003824)		0.0000000000025
55-183	PF01966 (IPR006674)	Metal-dependent phosphohydrolase, HD subdomain			0.00000000000017

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
5	379	374	- MYCGA7120	Mycoplasma gallisepticum	10	385	<1e-50	39.418	648
1	424	423	- MG461	Mycoplasma genitalium	1	424	<1e-50	72.8774	1703
7	311	304	- MSC_0132	Mycoplasma mycoides subsp. mycoides SC	7	289	6e-35	32.5806	351
5	262	257	- MYPE10360	Mycoplasma penetrans	26	266	6e-37	35.6061	370
6	402	396	-	Lactococcus lactis subsp. lactis KF147	5	384	2e-36	31.9712	368
6	266	260	-	Bacillus subtilis subsp. subtilis	16	261	5e-34	33.5849	350
6	266	260	-	Bacillus subtilis subsp. subtilis	14	259	1e-33	33.0827	348
25	189	164	-	Bacillus subtilis subsp. subtilis	19	159	0.000000001	30.1205	140
25	189	164	-	Bacillus subtilis subsp. subtilis	19	159	0.000000002	30.1205	139

Alias	ykiG
COG	COG1078R
EC number	3.1.-.-
Gene ID	877238
GI	13508416
GO	General function prediction only
Home COG	R
InterPro	IPR003607\|Metal-dependent phosphohydrolase, HD region
InterPro	IPR006674\|Metal-dependent phosphohydrolase, HD region, subdomain
Old MP number	MP165
Pathway	Protein degradation?
Pfam	PF01966
PID	g1673826
RefSeq	NP_110366.1
Swiss-Prot protein ID	Y677_MYCPN
phylomeDB tree	Y677_MYCPN
UniProt	P75115