MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene mtlD (MPN652)
Name 
mtlD
Stable ID 
MPN652
Location 
777463 - 778557 +
Sequence 
    1  ATGAAAAGAA TTAATGTATT GCACTTTGGC GCTGGTAATA TAGGTAGAGG TGTTATATTA
   61  CCGATTTACC AACAAAATGA CTTTTCCATT GATTTAGTGG AATTGAATCA AAATACAGTT
  121  AATGAGTTAC AAAAGCAAAA ACAATACCAA GTTCATTACC TTGATTGTGA TCAAAGTCAG
  181  TTAGTTAATG ACTTTAATAC TTGAAACTTA AAGGATGAAG CGAAGATTAT TGAACTAATG
  241  GAAAGAGCTG ATGTTATTTC CACTTCAATA GGTGCTAAAA ACTTAGCTAG TTTAAAAACT
  301  TTGTTTGACA AAGCTAAGTT CCATAAAAGG GCTATAGTGC TTTGCTTTGA AAACGGCTTT
  361  CGGATTAGTT CTAACTTTAA AAACATTTTG CAATTAAATA ACACACAAGT AAATTTTGTG
  421  GATGTGGTAA TCGATACAAT TGCACCTAAC TTCGAAAAGA AAGCGAATTT CTTGGATATT
  481  TATTGCGAGA AGTATTCAGA AATTTATGCT GAAACTTTCC CGCTAGAAAT TAAGGGAGTA
  541  AATCAAAAGA ATAGTTTAGA TAGATTCATT ATTAAAAAAC TTTTATTAGT CAATGCACTG
  601  CACAGTGTTA TTGGACTTTT AGGCTTTCAA CAAAAGCTTA AGTATGTACA TGAAACATTG
  661  CAAGTTAAAA GTAATTTGAC TTTTGTAGAA AAATTAGCCC AACAAATTAT TGATGCCCTT
  721  TGTGCTGAAT ATCCTGAATT TAATAAAAAT AATTTGTTAA GTTATGGCAA AAATAACTTA
  781  GTCCGTTTTG CTAATCCCAA GATTCAAGAT TTAAACACAC GCTTAATTAG GGAACCATTA
  841  CGTAAACTTA ACCAAAATGA ACGCTTTTAT GCCATTTATA AACTCTTTAA AAAGAATAAG
  901  ATTGCACTAA ATAATATTTT GCAAGTTTAT CTGATGGTTT TAAAAACTAA TATAACAGAT
  961  GATACCGAAA GCCAACAAAT TGCTAAATTA ATAAATGAAA AAGCTTGAAC AGAGTTAGCG
 1021  AAATTATCCA GTTTAGAAGA GTCAGAATGA AACCTAATTA AACAAGAATT AAGCCGTGAA
 1081  ATTACTAAAA AATAA
Download Sequence
Operon 
OP259
Operon location 
777470 - 778510
Protein (mpn652)
Name 
Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17)
Stable ID 
Mpn652
Molecular Weight 
40040
Isoelectric Point 
9
Localization 
Cytoplasm
Comment -
Sequence 
MKRINVLHFGAGNIGRGVILPIYQQNDFSIDLVELNQNTVNELQKQKQYQVHYLDCDQSQLVNDFNTWNLKDEAKIIELM
ERADVISTSIGAKNLASLKTLFDKAKFHKRAIVLCFENGFRISSNFKNILQLNNTQVNFVDVVIDTIAPNFEKKANFLDI
YCEKYSEIYAETFPLEIKGVNQKNSLDRFIIKKLLLVNALHSVIGLLGFQQKLKYVHETLQVKSNLTFVEKLAQQIIDAL
CAEYPEFNKNNLLSYGKNNLVRFANPKIQDLNTRLIREPLRKLNQNERFYAIYKLFKKNKIALNNILQVYLMVLKTNITD
DTESQQIAKLINEKAWTELAKLSSLEESEWNLIKQELSREITKK
Post translational modifications
No post translational modifications were found
GENE/PROTEIN mtlD (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
4-85 G3DSA:3.40.50.720 (IPR016040) NAD(P)-binding domain Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008152'>'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008152)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003824'>'catalytic' == '' ? '': 'catalytic'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003824) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005488'>'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005488)

0.0000033
4-184 SSF51735 (n.a.) NULL 0.0000000039
5-102 PF01232 (IPR013131) Mannitol dehydrogenase, N-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0055114'>'oxidation' == '' ? '': 'oxidation'; 'reduction' == '' ? '': 'reduction'; ('GO' == '' ? '': 'GO';:0055114)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016491'>'oxidoreductase' == '' ? '': 'oxidoreductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016491)

2.7e-19
136-353 PF08125 (IPR013118) Mannitol dehydrogenase, C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0055114'>'oxidation' == '' ? '': 'oxidation'; 'reduction' == '' ? '': 'reduction'; ('GO' == '' ? '': 'GO';:0055114)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016491'>'oxidoreductase' == '' ? '': 'oxidoreductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016491) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0050662'>'coenzyme' == '' ? '': 'coenzyme'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0050662)

0
185-362 SSF48179 (IPR008927) 6-phosphogluconate dehydrogenase, C-terminal-like Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016491'>'oxidoreductase' == '' ? '': 'oxidoreductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016491)

3.49999e-29
187-344 G3DSA:1.10.1040.10 (IPR013328) Dehydrogenase, multihelical Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016491'>'oxidoreductase' == '' ? '': 'oxidoreductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016491) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0050662'>'coenzyme' == '' ? '': 'coenzyme'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0050662)

1.4e-17
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
6 336 330 - MCJ_006410 Mycoplasma conjunctivae 3 335 <1e-50 36.5782 489
6 327 321 - Lactococcus lactis subsp. lactis KF147 4 348 1e-26 27.1429 283
6 337 331 - Bacillus subtilis subsp. subtilis 3 348 2e-23 27.0423 259
6 337 331 - Bacillus subtilis subsp. subtilis 3 348 4e-23 27.5281 256
4 335 331 - b3600 Escherichia coli 1 353 2e-23 26.1708 257
4 301 297 - MSC_0017 Mycoplasma mycoides subsp. mycoides SC 1 308 2e-25 30.4487 269
6 310 304 - MCAP_0032 Mycoplasma capricolum subsp. capricolum 3 317 3e-25 29.0625 267
4 333 329 - MHP7448_0549 Mycoplasma hyopneumoniae 7448 1 332 <1e-50 37.574 501
1 335 334 - Mycoplasma pulmonis 1 334 <1e-50 38.7574 575
External IDs
EC number 
1.1.1.17
Gene ID 
877028
GI 
13508391
GO 
Carbohydrate transport and metabolism
Home COG 
G
InterPro 
IPR013131|Mannitol dehydrogenase rossman, N-terminal
InterPro 
IPR013118|Mannitol dehydrogenase, C-terminal
InterPro 
IPR008927|6-phosphogluconate dehydrogenase, C-terminal-like
InterPro 
IPR000669|Mannitol dehydrogenase
Old MP number 
MP190
Pathway 
Metabolism energy, Sugars
PDB homologs 
1m2w_A
PDB homologs 
1lj8_A
Pfam 
PF08125
Pfam 
PF01232
PID 
g1673854
RefSeq 
NP_110341.1
Swiss-Prot protein ID 
MTLD_MYCPN
phylomeDB tree 
MTLD_MYCPN
UniProt 
P78008
Transcription
IMAGE BROWSERS

OPERON OP259 (Genomic Overview)
Region:777470-778510

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STRING image

STRING of Mpn652STRING legend

PDB image(s)

1m2w

PDB 1m2w

1lj8

PDB 1lj8
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