MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene mtlA (MPN651)
Name 
mtlA
Stable ID 
MPN651
Location 
776337 - 777476 +
Sequence 
    1  ATGTTTTTAG GTGTGATGAT ATTCGGCCCA ATTGCAGCGC TAATCTTAAA ACACACTGAA
   61  AAGTTTTGAA TTCACCGTAT TAAAAGTGGC TTTGAAATGC TGGTAAATAA TTTTTACCTT
  121  GGCTTTTTAG GTTTCGCCTT AATATTTCCT AGTTTTTACC TATCAATTTA CTTAATTGGT
  181  TACATTCAAT TAGGTTTAAA ACTGCTTGTT GAAATAATGC AACAGTACAA ACTTTATCCA
  241  ATAGCTGCCA TTGTGATAGA GCCGGCCAAA GTTTTATTCC TAAATAATGC CATTAACCAT
  301  GGCGTGCTAA CTCCATTAGG CTTACAACAA GTAAGAGACA GTGGTAAATC AATTCTTTTC
  361  TTATTGGAAT CAAATCCTGG TCCAGGTTTG GGTCTCCTTG TTGCTTTCTT AATCTTTTTC
  421  TTTAAACGTG ATAAAAAGCT TTCTAGTAAT GCGGCATCTT CTAGTCCTAT TCACCTCTTT
  481  GGTGGTATCC ATGAAGTTTA CTTTCCGTTT GTGCTATTAA AACCTGTGTT AATTCTGGCC
  541  ACAATTGCTG TTGGTGTTGT GGGAAACGGC ATTTTGCAAA TATTTAATGC TGGGACAATT
  601  GCACCAGTGT CACCTGGTTC TGTTATTGCT GGTTTTCTCC AAATTAATAA AACACCTTTA
  661  GATGTAGCTG GTTATGCTTT GGCACTCGTT TTATCAGCTG TAACTTCGTT GTTAATTTCG
  721  CTTTTATTAC TTTCTTTAAC ACGTAAAAAA CAATTGAAAA CACTGCAAGA AGCGCAAGCA
  781  CAAGTTGCAG AAATGAAGCA AACGCCTGCA AAAAAACCAA GACAAAAAGA TACTCCAGCA
  841  ATTGCTACAA AGATAGACTT TTCCCAAGTT ACCTTTGTTT GCGATGCAGG TATGGGTTCT
  901  TCTACTATGG GAGCAGCTAT ATTTAGAAAA GAACTAAAAA ATCAAAATAT TGAAGACATT
  961  ACAGTGATTA ATAAAGCAAT AGTTGATTTA AAAGATGAAA AGGTAATTAT TACCATTTCC
 1021  CAACTTTATG ATCGCGTAAA AGCGAAGCGT GCAGACGCTA CGATTTATAC CATCAATCAG
 1081  TTCTTAGATA AACAAGGCTA TTTAACTATT ATTGAAAAGA TTAAAAATGA AAAGAATTAA
Download Sequence
Operon 
OP258
Operon location 
776010 - 776360
Protein (mpn651)
Name 
PTS system mannitol-specific EIICB component (EIICB-Mtl) (EII-Mtl)
Stable ID 
Mpn651
Molecular Weight 
41690
Isoelectric Point 
10
Localization 
TMHMM
Comment Includes: Mannitol permease IIC component (PTS system mannitol-specific EIIC component); Mannitol-specific phosphotransferase enzyme IIB component (EC 2.7.1.69) (PTS system mannitol-specific EIIB component)
Sequence 
MFLGVMIFGPIAALILKHTEKFWIHRIKSGFEMLVNNFYLGFLGFALIFPSFYLSIYLIGYIQLGLKLLVEIMQQYKLYP
IAAIVIEPAKVLFLNNAINHGVLTPLGLQQVRDSGKSILFLLESNPGPGLGLLVAFLIFFFKRDKKLSSNAASSSPIHLF
GGIHEVYFPFVLLKPVLILATIAVGVVGNGILQIFNAGTIAPVSPGSVIAGFLQINKTPLDVAGYALALVLSAVTSLLIS
LLLLSLTRKKQLKTLQEAQAQVAEMKQTPAKKPRQKDTPAIATKIDFSQVTFVCDAGMGSSTMGAAIFRKELKNQNIEDI
TVINKAIVDLKDEKVIITISQLYDRVKAKRADATIYTINQFLDKQGYLTIIEKIKNEKN
Post translational modifications
No post translational modifications were found
GENE/PROTEIN mtlA (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-253 PS51104 (IPR013014) Phosphotransferase system, EIIC component, type 2 12.472
226-255 seg (n.a.) NULL n.a. 0
248-269 coil (n.a.) NULL n.a. 0
285-377 SSF52794 (n.a.) NULL 1.1e-16
288-378 G3DSA:3.40.50.10370 (n.a.) NULL 3.1e-27
288-379 PS51099 (IPR013011) Phosphotransferase system, EIIB component, type 2 Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009401'>'phosphoenolpyruvate' == '' ? '': 'phosphoenolpyruvate';-'dependent' == '' ? '': 'dependent'; 'sugar' == '' ? '': 'sugar'; 'phosphotransferase' == '' ? '': 'phosphotransferase'; 'system' == '' ? '': 'system'; ('GO' == '' ? '': 'GO';:0009401)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005351'>'sugar' == '' ? '': 'sugar';:'hydrogen' == '' ? '': 'hydrogen'; 'symporter' == '' ? '': 'symporter'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0005351) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008982'>'protein' == '' ? '': 'protein';-'N' == '' ? '': 'N';('PI' == '' ? '': 'PI';)-'phosphohistidine' == '' ? '': 'phosphohistidine';-'sugar' == '' ? '': 'sugar'; 'phosphotransferase' == '' ? '': 'phosphotransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008982)

12.924
290-370 PF02302 (IPR003501) Phosphotransferase system, EIIB component, type 2/ Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009401'>'phosphoenolpyruvate' == '' ? '': 'phosphoenolpyruvate';-'dependent' == '' ? '': 'dependent'; 'sugar' == '' ? '': 'sugar'; 'phosphotransferase' == '' ? '': 'phosphotransferase'; 'system' == '' ? '': 'system'; ('GO' == '' ? '': 'GO';:0009401)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008982'>'protein' == '' ? '': 'protein';-'N' == '' ? '': 'N';('PI' == '' ? '': 'PI';)-'phosphohistidine' == '' ? '': 'phosphohistidine';-'sugar' == '' ? '': 'sugar'; 'phosphotransferase' == '' ? '': 'phosphotransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008982)

0.0000015
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
1 375 374 - MCJ_006420 Mycoplasma conjunctivae 110 477 <1e-50 48.5411 891
1 379 378 - Lactococcus lactis subsp. lactis KF147 110 492 <1e-50 35.3535 561
1 375 374 - Bacillus subtilis subsp. subtilis 102 477 <1e-50 41.9437 675
1 375 374 - Bacillus subtilis subsp. subtilis 102 477 <1e-50 41.5385 680
1 374 373 - b3599 Escherichia coli 96 465 <1e-50 36.7725 601
1 377 376 - b2933 Escherichia coli 97 459 <1e-50 36.3402 532
3 367 364 - MCAP_0458 Mycoplasma capricolum subsp. capricolum 157 512 <1e-50 31.9892 462
2 378 376 - MCAP_0028 Mycoplasma capricolum subsp. capricolum 135 511 <1e-50 35.9173 513
1 367 366 - MHP7448_0550 Mycoplasma hyopneumoniae 7448 110 474 <1e-50 51.6043 962
2 378 376 - MSC_0021 Mycoplasma mycoides subsp. mycoides SC 136 513 <1e-50 35.6589 508
289 378 89 - MYCGA3630 Mycoplasma gallisepticum 162 252 0.00000000002 38.4615 147
33 378 345 - Mycoplasma pulmonis 1 341 <1e-50 53.7356 841
External IDs
COG 
COG2213G
EC number 
2.7.1.69
Gene ID 
877002
GI 
13508390
GO 
Carbohydrate transport and metabolism
Home COG 
G
InterPro 
IPR003501|Phosphotransferase system, lactose/cellobiose-specific IIB subunit
InterPro 
IPR013011|Phosphotransferase system, EIIB component, type 2
InterPro 
IPR013014|Phosphotransferase system, EIIC component, type 2
InterPro 
IPR003352|Phosphotransferase system, EIIC
Old MP number 
MP191
Pathway 
Transporter, PTS
PDB homologs 
1iib_A
PDB homologs 
1h9c_A
PDB homologs 
1e2b_
Pfam 
PF02378
Pfam 
PF02302
PID 
g1673855
RefSeq 
NP_110340.1
Swiss-Prot protein ID 
PTMCB_MYCPN
phylomeDB tree 
PTMCB_MYCPN
UniProt 
P75146
Transcription
IMAGE BROWSERS

OPERON OP258 (Genomic Overview)
Region:776010-776360

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STRING image

STRING of Mpn651STRING legend

PDB image(s)

1iib

PDB 1iib

1h9c

PDB 1h9c

1e2b

PDB 1e2b
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