MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene outB (MPN562)
Name 
outB
Stable ID 
MPN562
Location 
682485 - 683231 -
Sequence 
    1  ATGACTAAAA ATTTATTGAA CTATTTAAAC GAATTGGAAG CTTGACTCAC CAATTACGTT
   61  AATGAAGCTC ACGCTCAGGG CGTGGTTGTT GGATTGTCAG GTGGAGTTGA TTCGGCAGTT
  121  GTAGCCGCCA TGACTAAAAA ACTGTTTCCG CAAAACCACT TAACCTTGGT AATGCACATT
  181  AATAACTCCG AGTTAGATCA CAAGGCCACA ACTGCCTTAG TGGAACAATT ACAACTCAAC
  241  AATAAACAGG TGGATTTAGA ACCACCTTAC CGCGCTATGT TGCAAGCATT GACCATTGAT
  301  CCCCAAAAGG AGTTAATGGT AGCCGGCAAC CTCAAAGCAC GTTTACGAAT GGCTTGTCTA
  361  TACACCCATG CCCAAAAGCA CAACTACTTA GTTTTGGGTA CTGGCAACTT CATTGAGTAC
  421  AGCTTGGGCT ACTTTACTAA ATGGGGTGAT GGGGCGTGTG ATGTGGCACC CTTAGCGTTC
  481  TTGTTAAAGA GCGATGTTTA TGCTTTATCC CAGCACTTCA ATGTTCCTGA ATTGGTCATT
  541  GAACGAGCCC CTACTGCTAG TCTGTTTGCC GGGCAGACTG ACGAAGCGGA AATGGGTTTG
  601  ACGTATAAGG AATTGGACCA GTACTTTCAG GGCCACTTAC AGTTAAGTGC CACGAAACAA
  661  CAACGGGTTG ACCACTTGCG CCAAAGCTCC CAGCACAAGC GTAGTTTACC TAAAACCTTT
  721  AAACCACTTT ATTCCTTCCA AATCTAG
Download Sequence
Operon 
OP349
Operon location 
682000 - 685822
Protein (mpn562)
Name 
Probable NH(3)-dependent NAD(+) synthetase (EC 6.3.1.5)
Stable ID 
Mpn562
Molecular Weight 
27280
Isoelectric Point 
7
Localization 
Cytoplasm
Comment probable NH(3)-dependent NAD(+) synthetase;, cofactors; NAD synthase; ATP + deamido-NAD(+) +NH3 = AMP + diphosphate + NAD+; L-glutamine also acts, more slowly, as amido-donor (cf. EC 6.3.5.1).
Sequence 
MTKNLLNYLNELEAWLTNYVNEAHAQGVVVGLSGGVDSAVVAAMTKKLFPQNHLTLVMHINNSELDHKATTALVEQLQLN
NKQVDLEPPYRAMLQALTIDPQKELMVAGNLKARLRMACLYTHAQKHNYLVLGTGNFIEYSLGYFTKWGDGACDVAPLAF
LLKSDVYALSQHFNVPELVIERAPTASLFAGQTDEAEMGLTYKELDQYFQGHLQLSATKQQRVDHLRQSSQHKRSLPKTF
KPLYSFQI
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation AmLQALTIDPQK 92 104 M
Oxidation AMLQALTIDPQKELmVAGNLK 92 113 M
Oxidation AmLQALTIDPQKELmVAGNLK 92 113 M
GENE/PROTEIN outB (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
4-247 TIGR00552 (IPR003694) NAD synthase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009435'>'NAD' == '' ? '': 'NAD'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009435)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003952'>'NAD' == '' ? '': 'NAD';+ 'synthase' == '' ? '': 'synthase'; ('glutamine' == '' ? '': 'glutamine';-'hydrolyzing' == '' ? '': 'hydrolyzing';) 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003952) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

0
7-238 G3DSA:3.40.50.620 (IPR014729) Rossmann-like alpha/beta/alpha sandwich fold 0
7-247 SSF52402 (n.a.) NULL 0
9-237 PF02540 (IPR022310) NAD/GMP synthase 0
97-237 PTHR23090:SF2 (n.a.) NULL 6.10003e-39
97-237 PTHR23090 (n.a.) NULL 6.10003e-39
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
106 239 133 - b1740 Escherichia coli 132 267 0.000000000000007 34.3066 181
73 234 161 - MARTH_orf282 Mycoplasma arthritidis 88 246 1e-32 38.8889 328
8 235 227 - MAG6600 Mycoplasma agalactiae 25 252 2e-36 34.9345 361
8 235 227 - MCJ_006050 Mycoplasma conjunctivae 7 231 3.00018e-42 35.0877 411
1 242 241 - MCAP_0531 Mycoplasma capricolum subsp. capricolum 9 248 9.80909e-45 39.9177 432
4 247 243 - MG383 Mycoplasma genitalium 3 247 <1e-50 55.102 745
3 243 240 - MHP7448_0473 Mycoplasma hyopneumoniae 7448 5 243 8e-40 33.4711 391
9 238 229 - MHO_1800 Mycoplasma hominis 22 249 1e-29 29.0043 302
8 175 167 - MMOB1920 Mycoplasma mobile 4 169 0.00000000000004 26.6272 169
1 242 241 - MSC_0440 Mycoplasma mycoides subsp. mycoides SC 11 250 2.94273e-44 39.5062 429
1 240 239 - MYPE1940 Mycoplasma penetrans 1 235 6e-36 32.5 358
109 237 128 - Lactococcus lactis subsp. lactis KF147 135 265 1e-18 37.1212 211
109 240 131 - Bacillus subtilis subsp. subtilis 133 266 8e-20 36.2963 226
109 240 131 - Bacillus subtilis subsp. subtilis 131 264 8e-20 36.2963 226
3 247 244 - Mycoplasma pulmonis 12 253 1e-36 34.1463 364
External IDs
COG 
COG0171H
EC number 
6.3.1.5
Gene ID 
876904
GI 
13508301
GO 
Coenzyme metabolism
Home COG 
H
InterPro 
IPR003694|NAD+ synthase
Old MP number 
MP280
Pathway 
Metabolism nucleotide
PDB homologs 
1NSY-A
PDB homologs 
1ee1_A
PDB homologs 
1fyd_A
PDB homologs 
1gpm_A
Pfam 
PF02540
Pfam 
PF03054
Pfam 
PF06508
PID 
g1673951
RefSeq 
NP_110251.1
Swiss-Prot protein ID 
NADE_MYCPN
phylomeDB tree 
NADE_MYCPN
UniProt 
P75216
Transcription
IMAGE BROWSERS

OPERON OP349 (Genomic Overview)
Region:682000-685822

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STRING image

STRING of Mpn562STRING legend

PDB image(s)

1NSY

PDB 1NSY

1ee1

PDB 1ee1

1fyd

PDB 1fyd

1gpm

PDB 1gpm
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