Gene ygl3 (MPN521)
Name
ygl3
Stable ID
MPN521
Location
642760 - 643260 +
Sequence
    1  ATGTATAAAT CAGCGATTAA TATCGTCTTA TTTTGCCCAG AAATTCCTAA TAACACTGGG
   61  AACATTGTTC GGAGCTGTAC CGCTTTTAAA GCTAACTTGC ATCTGATTAA GCCCTATGGC
  121  TTTTTTCTCA ATGATAAGCG GATGGTGCGT GCTGGGTTAA ATTGTTGGGA TAAGGTGCAA
  181  ATGTTTGAAC ACAAATCCTG GGAACACTTC ATTGAAACAA CACCACCAAA TAAAGCAATT
  241  TGGTTGTTGA CAAAGAGTGG TACTACTACC CCAGACCAAA TTAACATGCA AACAGATAAC
  301  AGGGAACAAC TGTACTTTGT TTTTGGTCAA GAAACCAAGG GATTACCGCA AACACTCATG
  361  GAACAATACT CGCAGAACCA GGTACGGATT CCGATTTGAA ACCCTGTAAG AAGCATTAAC
  421  TTGTCCAATA CAGTAGCTTG TGTACTGTAT GAGTATGCTA AACAAAATCA TTACTTTAAT
  481  TTAGATAAAC AGTGCGCTTA A
Download Sequence
Operon
OP220
Operon location
642770 - 643900
Protein (mpn521)
Name
Probable tRNA/rRNA methyltransferase  SpoU (EC 2.1.1.-)
Stable ID
Mpn521
Molecular Weight
18260
Isoelectric Point
9
Localization
Cytoplasm
Comment tRNA modification position 34 (wobble). C->Cm ( 2-O-methylcytidine), U->Um (2-O-methyluridine); cofactor: SAM
Sequence
MYKSAINIVLFCPEIPNNTGNIVRSCTAFKANLHLIKPYGFFLNDKRMVRAGLNCWDKVQMFEHKSWEHFIETTPPNKAI
WLLTKSGTTTPDQINMQTDNREQLYFVFGQETKGLPQTLMEQYSQNQVRIPIWNPVRSINLSNTVACVLYEYAKQNHYFN
LDKQCA
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation SGTTTPDQINmQTDNR 86 102 M
Oxidation SGTTTPDQINmQTDNREQLYFVFGQETK 86 114 M
Oxidation GLPQTLmEQYSQNQVR 114 130 M
GENE/PROTEIN ygl3 (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-162 PIRSF029256 (IPR016914) S-adenosyl-L-methionine dependent tRNA/rRNA methyl 0
3-162 PTHR12029 (n.a.) NULL 1.40001e-35
3-162 PTHR12029:SF11 (n.a.) NULL 1.40001e-35
5-162 TIGR00185 (IPR004440) RNA methyltransferase TrmH, group 2 Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006396'>'RNA' == '' ? '': 'RNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0006396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008173'>'RNA' == '' ? '': 'RNA'; 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008173)

0
5-164 SSF75217 (n.a.) NULL 6.39999e-35
6-150 PF00588 (IPR001537) tRNA/rRNA methyltransferase, SpoU Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006396'>'RNA' == '' ? '': 'RNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0006396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003723'>'RNA' == '' ? '': 'RNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003723) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008173'>'RNA' == '' ? '': 'RNA'; 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008173)

3.7e-30
6-161 G3DSA:3.40.1280.10 (n.a.) NULL 5.60519e-45
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
6 161 155 - MAG0850 Mycoplasma agalactiae 2 159 1e-23 34.5912 248
6 163 157 - MARTH_orf364 Mycoplasma arthritidis 2 161 1e-25 36.646 265
6 159 153 - Caulobacter crescentus NA1000 1 150 2e-17 31.2102 200
6 163 157 - MHO_2210 Mycoplasma hominis 2 161 7e-24 36.8098 250
7 162 155 - Lactococcus lactis subsp. lactis KF147 3 158 3e-30 38.2166 309
5 161 156 - Bacillus subtilis subsp. subtilis 5 159 5e-31 42.6752 320
5 161 156 - Bacillus subtilis subsp. subtilis 2 156 5e-31 42.6752 320
8 158 150 - MT3475 Mycobacterium tuberculosis 4 150 2e-20 33.5526 228
6 158 152 - b3606 Escherichia coli 2 150 2e-27 38.961 288
1 166 165 - MG346 Mycoplasma genitalium 1 166 <1e-50 79.5181 737
1 163 162 - MCAP_0364 Mycoplasma capricolum subsp. capricolum 1 161 2e-26 34.3558 273
6 155 149 - MS53_0568 Mycoplasma synoviae 2 153 5e-23 34.6405 243
6 163 157 - MHP7448_0143 Mycoplasma hyopneumoniae 7448 2 161 7e-25 35.1852 260
6 163 157 - MMOB1210 Mycoplasma mobile 2 160 5e-26 37.8882 269
1 163 162 - MSC_0615 Mycoplasma mycoides subsp. mycoides SC 1 161 5e-27 34.9693 279
5 155 150 - LIC_12943 Leptospira interrogans serovar Copenhage 2 149 6e-25 35.5263 265
4 161 157 - MYCGA3180 Mycoplasma gallisepticum 3 162 7e-40 43.125 389
6 152 146 - MYPE100 Mycoplasma penetrans 2 151 2e-36 46 362
6 163 157 - Mycoplasma pulmonis 2 162 8e-26 36.4198 268
External IDs
COG
COG0219J
EC number
2.1.1.-
Gene ID
876885
GI
13508260
GO
Translation, ribosomal structure and biogenesis
Home COG
J
InterPro
IPR001537|tRNA/rRNA methyltransferase, SpoU
InterPro
IPR004440|RNA methyltransferase TrmH, group 2
Old MP number
MP321
Pathway
tRNA metabolism
Pfam
PF00588
PID
g1673994
RefSeq
NP_110209.1
Swiss-Prot protein ID
Y521_MYCPN
phylomeDB tree
Y521_MYCPN
UniProt
P75257
Transcription
IMAGE BROWSERS

OPERON OP220 (Genomic Overview)
Region:642770-643900

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STRING image

STRING of Mpn521STRING legend