MyMpn Project

Name	mpn464
Stable ID	MPN464
Location	566891 - 568228 +
Sequence	1 ATGGCTGCTG TTACAGACAA TCAGCAATCA GGTGATAACA ATGGATTGGT ATCGCTTGCA 61 CAGCGCTCCA CTACTGTTGC TGTCCAAAAA AGTGACTCTT CTGGTTCTCA AGGCCAAGGC 121 ACAACCGACA ACAAATTCCA AAAATATTTA AACACCACCC AGGCCCTGCA CCAGATGGGG 181 GTGATAGTGC CATCTTTGGA AACGTGACCT GGTAAACCAA GTACTGGAAT CGCTACCCGT 241 GCTGCTGGTG GTGTTTCAGT CCAAGCAGCG ACCCGGCAAT CGACTTCTAC AAATGAAGAT 301 TTGTCGAATG TAATAACACA GCTTTATCAT ACCTCCACGT CCCAACTCGC TTACTTAAAT 361 GGCCAGATAG TTGTGATGGG CTCAGACCGG GTACCGAGTT TGTGGTATTG GGTCGTGGAT 421 GAGCGAACCA CGTCCGGGAG GGCGACTTGA TGAGCCCACA CCGAGCTCAA CTGGGGCACC 481 GACAAGCAGA AGCAGTTTGT CGAAAACCAG TTGGGGTTTA AAGATGACTC AAATTCGGAT 541 TCCAAAAATT CGAATTTGAA GGCCCAAGGC CTCACCCAAC CCGCCTACCT CATCGCCGGT 601 CTTGACGTTG TGGCCGACCA CCTCGTCTTT GCGGCCTTCA AAGCGGGGGC AGTGGGGTAT 661 GATATGACGA CTGATTCGAA CGCTTCCACC AAAGACCAAG TGCTCGCCTG GTCGACCACG 721 GCCGGATTGG ACAGTGATGG GGGGTACAAG GCCTTGGTGG AAAACACGGC CGGATTGAAC 781 GGACCGATTA ATGGCTTGTT TATCCTGTTA GACACCTTTG CCTATGTGAC CCCGGTGAGT 841 GGGATGAAAG GGGGGAGTAA GAATACGGAG GCAGTGCAAA CCAAGTATCC CGTTAAGGAT 901 GATAGTAAGG CGAGTGCCAA AATTGCTTCC TTAATTAATG CCAGTCCACT CAACAGTTAT 961 GGGGATGATG GCGTGACCGT GTTTGATGCC CTGGGCCTTA ACTTTAACTT TAAGTTGGAC 1021 GAGGCGCGCT TGCCATCGCG CACCGACCAA CTGCTTGTGT ATGGGATTGT AAACGAAAGT 1081 GAACTGAAGT CCGCGCGCGA AAATGCCCAG TCGACATCCG ATGATAATTC AAACACCAAA 1141 GTCAAGTGAA CTAACACCGC CTCGCACTAC CTCCCCGTGC CGTATTACTA CAGTGCCAAT 1201 TTCCCCGAAG CGGGTAACAG GAGAAGAGCG GAGCAGCGGA ATGGGGTGAT AACAATAAAA 1261 AAAGCCATCT ACCCAGAGGT AAGAGGCAGA CAGCTCCAAA ATATTTTTGA CGATTGGAAA 1321 ACTAACAAAA GCCGTTAG
Download Sequence
Operon	OP200
Operon location	564380 - 568200

MAAVTDNQQSGDNNGLVSLAQRSTTVAVQKSDSSGSQGQGTTDNKFQKYLNTTQALHQMGVIVPSLETWPGKPSTGIATR

AAGGVSVQAATRQSTSTNEDLSNVITQLYHTSTSQLAYLNGQIVVMGSDRVPSLWYWVVDERTTSGRATWWAHTELNWGT

DKQKQFVENQLGFKDDSNSDSKNSNLKAQGLTQPAYLIAGLDVVADHLVFAAFKAGAVGYDMTTDSNASTKDQVLAWSTT

AGLDSDGGYKALVENTAGLNGPINGLFILLDTFAYVTPVSGMKGGSKNTEAVQTKYPVKDDSKASAKIASLINASPLNSY

GDDGVTVFDALGLNFNFKLDEARLPSRTDQLLVYGIVNESELKSARENAQSTSDDNSNTKVKWTNTASHYLPVPYYYSAN

FPEAGNRRRAEQRNGVITIKKAIYPEVRGRQLQNIFDDWKTNKSR

Approximately 4% of the limited M.�genitalium genome contains repeat sequences termed MgPar regions that have homology to mgpB and mgpC, which encode antigenic proteins associated with attachment. We have previously shown that mgpB sequences vary within a

Name	Putative mgpC-like protein MPN_464
Stable ID	Mpn464
Molecular Weight	48950
Isoelectric Point	7
Localization	SECRETOMEP
Comment	Approximately 4% of the limited M.�genitalium genome contains repeat sequences termed MgPar regions that have homology to mgpB and mgpC, which encode antigenic proteins associated with attachment. We have previously shown that mgpB sequences vary within a single strain of M.�genitalium in a pattern consistent with recombination between mgpB and MgPar sequences (Iverson-Cabral et�al.). In the current study, we show that mgpC heterogeneity similarly occurs within the type strain, G-37T, cultured in vitro and among cervical specimens collected from a persistently infected woman. In all cases, alternative mgpC sequences are indicative of recombination with MgPar regions
Sequence	MAAVTDNQQSGDNNGLVSLAQRSTTVAVQKSDSSGSQGQGTTDNKFQKYLNTTQALHQMGVIVPSLETWPGKPSTGIATR AAGGVSVQAATRQSTSTNEDLSNVITQLYHTSTSQLAYLNGQIVVMGSDRVPSLWYWVVDERTTSGRATWWAHTELNWGT DKQKQFVENQLGFKDDSNSDSKNSNLKAQGLTQPAYLIAGLDVVADHLVFAAFKAGAVGYDMTTDSNASTKDQVLAWSTT AGLDSDGGYKALVENTAGLNGPINGLFILLDTFAYVTPVSGMKGGSKNTEAVQTKYPVKDDSKASAKIASLINASPLNSY GDDGVTVFDALGLNFNFKLDEARLPSRTDQLLVYGIVNESELKSARENAQSTSDDNSNTKVKWTNTASHYLPVPYYYSAN FPEAGNRRRAEQRNGVITIKKAIYPEVRGRQLQNIFDDWKTNKSR

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
8-92	PD008387 (n.a.)	NULL			0
126-351	PF05220 (IPR007885)	MgpC			0

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
46	435	389	- MG192	Mycoplasma genitalium	265	625	<1e-50	47.8697	901

Gene ID	876799
GI	13508203
GO	Cell envelope biogenesis, outer membrane
Home COG	M
InterPro	Approximately 4% of the limited M.�genitalium genome contains repeat sequences termed MgPar regions that have homology to mgpB and mgpC, which encode antigenic proteins associated with attachment. We have previously shown that mgpB sequences vary within a
Old MP number	MP377
Pathway	Adhesion
Pfam	PF05220
Pfam	PF08372
PID	g1674057
RefSeq	NP_110152.1
Swiss-Prot protein ID	Y464_MYCPN
phylomeDB tree	Y464_MYCPN
UniProt	P75319