MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene mnmA (MPN422)
Name 
mnmA
Stable ID 
MPN422
Location 
508751 - 509863 -
Sequence 
    1  ATGCAAAATA AAACCGTTTT TGTCGGAATA TCAGGTGGAG TGGACTCAGC TGTGAGTGCG
   61  CTCCTTTTAA AGCAACAGTA CCGCGAAGTG ATTGGCATTT TTATGGAGTG CTGGGACAAT
  121  ACACTAAATA ACGACCAGTT AGGTCACCGC GCCTTTAACG AGCATAAGTC GGGTTGTTCG
  181  TCCAAAGAAG ATTTTCGCGA AGCGCAAGCA ATTGCCCAAT TACTAGGAAT CAAACTAATT
  241  AAGCAAAACC TGGTGGAACC GTACTGAAAG CAGGTATTTC TCCCTACCAT TGATGCCTTT
  301  AAAAACGGGT TAACCCCTAA CCCCGACATG TTGTGTAACC GTTTAATTAA ATTTGGGCTA
  361  ATGCGTGATT ACTGCAAGCA GTTAGATCCC AACAGTGACT TTGCTACAGG GCATTATGCG
  421  GCACTTAGCT GGGACAACAA CCAACCTTTA CTGGCCATTC CCAAAGACAA GCACAAGGAC
  481  CAAACCTATT TTTTAGCGCA TGTCAAACCA GCGCAACTAC AAGACGTGGT GTTTCCCTTG
  541  GCGCATTTAC TGAAAACGGA GGTGCGGCAA ATAGCGTTAG CACACCACTT TAGTGTGGCT
  601  ACTAAAAAGG ACTCAACCGG CATTTGCTTT ATTGGGGAAC GCCACTTTAG TGACTTCTTA
  661  AAGAATTATT TACCAGTCAA ACCGGGGGTT ATTTATGATT GAAAAACGCA GCGCCAACTA
  721  GGCAGTCATG AAGGGGTGTG ATTTTACACC ACTGGGCAGC GCAGTGGCTT AAATTTAGGT
  781  GGGCAAGCAG CACGGAACTT TGTCGTTGAA AAGGACTTAA AAACAAACAC CTTGTATGTC
  841  TCGAGTGACC CAGAAGATTT ACAGCGTCGT GGCATTACCC TTTCCCACTT TAACTGGTTG
  901  TACCAACCCA ATCCATTGAC CCAAACCGTT CTGGTACGGA TTCGCCATGC CCAACCGTTA
  961  GTGCAAGGGC ACATAACAGT ACAACCAAAC AACGTCGTGC AAGTACAACT AGATCAACCA
 1021  ATTGACCGCG TTACCAACGG TCAGTATGGT GTTTTGTATA CCCAGAATGG CATTTGTTTG
 1081  GGGAGTGGTA TCATTACCGC TAGCCAAATC TAA
Download Sequence
Operon 
OP422
Operon location 
508682 - 510255
Protein (mpn422)
Name 
tRNA-specific 2-thiouridylase mnmA (EC 2.8.1.-)
Stable ID 
Mpn422
Molecular Weight 
40700
Isoelectric Point 
9
Localization 
Cytoplasm
Comment (RN:R00601) S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNAcontaining 5-methylaminomethyl-2-thiouridylate
Sequence 
MQNKTVFVGISGGVDSAVSALLLKQQYREVIGIFMECWDNTLNNDQLGHRAFNEHKSGCSSKEDFREAQAIAQLLGIKLI
KQNLVEPYWKQVFLPTIDAFKNGLTPNPDMLCNRLIKFGLMRDYCKQLDPNSDFATGHYAALSWDNNQPLLAIPKDKHKD
QTYFLAHVKPAQLQDVVFPLAHLLKTEVRQIALAHHFSVATKKDSTGICFIGERHFSDFLKNYLPVKPGVIYDWKTQRQL
GSHEGVWFYTTGQRSGLNLGGQAARNFVVEKDLKTNTLYVSSDPEDLQRRGITLSHFNWLYQPNPLTQTVLVRIRHAQPL
VQGHITVQPNNVVQVQLDQPIDRVTNGQYGVLYTQNGICLGSGIITASQI
Post translational modifications
No post translational modifications were found
GENE/PROTEIN mnmA (Domains Overview)
Click on the features to jump to domain info

 ExportIMG
Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-255 SSF52402 (n.a.) NULL 9.99967e-42
2-221 G3DSA:3.40.50.620 (IPR014729) Rossmann-like alpha/beta/alpha sandwich fold 0
4-365 TIGR00420 (IPR004506) tRNA-specific 2-thiouridylase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008033'>'tRNA' == '' ? '': 'tRNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0008033)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005737'>'cytoplasm' == '' ? '': 'cytoplasm'; ('GO' == '' ? '': 'GO';:0005737)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016740'>'transferase' == '' ? '': 'transferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016740)

0
4-365 PF03054 (IPR004506) tRNA-specific 2-thiouridylase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008033'>'tRNA' == '' ? '': 'tRNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0008033)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005737'>'cytoplasm' == '' ? '': 'cytoplasm'; ('GO' == '' ? '': 'GO';:0005737)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016740'>'transferase' == '' ? '': 'transferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016740)

0
19-365 PTHR11933 (IPR004506) tRNA-specific 2-thiouridylase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008033'>'tRNA' == '' ? '': 'tRNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0008033)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005737'>'cytoplasm' == '' ? '': 'cytoplasm'; ('GO' == '' ? '': 'GO';:0005737)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016740'>'transferase' == '' ? '': 'transferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016740)

0
223-283 G3DSA:2.30.30.280 (n.a.) NULL 3e-19
287-367 G3DSA:2.40.30.10 (n.a.) NULL 0.000000000000001
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
4 365 361 - MAG4170 Mycoplasma agalactiae 5 361 <1e-50 44.0541 698
4 364 360 - MARTH_orf201 Mycoplasma arthritidis 3 357 <1e-50 41.4835 666
2 368 366 - Caulobacter crescentus NA1000 36 401 2e-36 30.5263 369
6 370 364 - MCJ_001010 Mycoplasma conjunctivae 4 356 <1e-50 40.8602 661
4 364 360 - MHO_1300 Mycoplasma hominis 3 357 <1e-50 40.3846 664
6 365 359 - Lactococcus lactis subsp. lactis KF147 11 363 <1e-50 39.3531 568
2 365 363 - Bacillus subtilis subsp. subtilis 9 361 <1e-50 37.8378 599
2 365 363 - Bacillus subtilis subsp. subtilis 6 358 <1e-50 37.5676 595
4 365 361 - b1133 Escherichia coli 6 360 <1e-50 37.7358 556
4 365 361 - MG295 Mycoplasma genitalium 6 367 <1e-50 63.2597 1257
6 353 347 - Rv3024c Mycobacterium tuberculosis 3 338 2e-33 31.6384 343
6 365 359 - MCAP_0523 Mycoplasma capricolum subsp. capricolum 5 370 <1e-50 41.2399 685
1 365 364 - MS53_0375 Mycoplasma synoviae 1 359 <1e-50 42.2764 670
6 364 358 - MHP7448_0430 Mycoplasma hyopneumoniae 7448 4 358 <1e-50 41.3223 657
6 368 362 - MMOB4400 Mycoplasma mobile 4 360 <1e-50 39.5095 640
6 365 359 - MSC_0447 Mycoplasma mycoides subsp. mycoides SC 5 370 <1e-50 42.0912 707
1 370 369 - LIC_12269 Leptospira interrogans serovar Copenhage 1 362 1e-37 30.7692 379
6 366 360 - MYCGA1200 Mycoplasma gallisepticum 289 653 <1e-50 43.5967 733
4 365 361 - MYPE8250 Mycoplasma penetrans 2 364 <1e-50 47.0109 825
6 365 359 - Mycoplasma pulmonis 4 357 <1e-50 40.0545 679
External IDs
COG 
COG0482J
EC number 
2.1.1.61
EC number 
2.8.1.-
Gene ID 
877362
GI 
13508161
GO 
Translation, ribosomal structure and biogenesis
Home COG 
J
InterPro 
IPR004506|tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase
Old MP number 
MP419
Pathway 
tRNA Metabolism
PDB homologs 
1GPM-A
PDB homologs 
1j21_A
PDB homologs 
1j1z_A
PDB homologs 
1j20_A
Pfam 
PF02540
Pfam 
PF03054
Pfam 
PF06508
PID 
g1674103
RefSeq 
NP_110110.1
Swiss-Prot protein ID 
MNMA_MYCPN
phylomeDB tree No orthologous found
UniProt 
P75365
Transcription
IMAGE BROWSERS

OPERON OP422 (Genomic Overview)
Region:508682-510255

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STRING image

STRING of Mpn422STRING legend

PDB image(s)

1GPM

PDB 1GPM

1j21

PDB 1j21

1j1z

PDB 1j1z

1j20

PDB 1j20
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All data provided for download in the MyMpn database is free to use. Upon doing so, please cite the original data source and the MyMpn database
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