MyMpn Project

1 ATGAGATGAA GTGACTCTGA AAACAATAAA ATCGACTATA TTGAAGACTT TGCAACTCAT 61 TTTTTAAACA AAAACGCCTT ATTAAACGTT ATTTGTAAAT TTTGTGTGTT CAGGTCAAAT 121 AGTGATCTTT GAGTTATGCG TCCTTACCAA ATATGCGCAA CTGAAAGAAT TTTAGAAAAA 181 ATAAAAGAAG ACAATAGGAA CAGTAAAAAC TCTAAAAATG CAAGTAAGGG CGGCTGTATT 241 TGACACTCAA CCGGAAGTGG TAAAACACTA ACTTCTTTTA AAGCTGTTCA ATTGGCTAGT 301 GAAATAGACT TTGTTGATAA AGTCCTTTTC GTTGTTGACA GGAAAGACTT GGACAACCAA 361 ACGATCGAAG AATATGAAAA GTTTCAAGCG GGTTCTGTTA GCGAAACTGA GAACACAAAT 421 GATCTTAAAG AAAAGATATT AGACGATAGT ACCGCCACAC GTGCAATTGT TACTACTATT 481 CATAAACTTA AGAGGTTAAT AGATCAGAGA AGTAAGCTTA AAGACGAAGA TCTTAAAAAG 541 AAAAACATCG TTCTTATATT CGATGAATGT CATCGATCTC AATTTGGAAA AATGAAACAA 601 GAAATCGATG AGTTTTTTTA A

MRWSDSENNKIDYIEDFATHFLNKNALLNVICKFCVFRSNSDLWVMRPYQICATERILEKIKEDNRNSKNSKNASKGGCI

WHSTGSGKTLTSFKAVQLASEIDFVDKVLFVVDRKDLDNQTIEEYEKFQAGSVSETENTNDLKEKILDDSTATRAIVTTI

HKLKRLIDQRSKLKDEDLKKKNIVLIFDECHRSQFGKMKQEIDEFF

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
1-196	SSF52540 (n.a.)	NULL			4.3e-28
42-205	SM00487 (IPR014001)	DEAD-like helicase, N-terminal			0.0047
46-195	G3DSA:3.40.50.300 (n.a.)	NULL			2.8e-17
46-205	PF04851 (IPR006935)	Restriction endonuclease, type I, R subunit/Type I	Molecular Function: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016787'>'hydrolase' == '' ? '': 'hydrolase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016787)		2.1e-29

Name	hsdR
Stable ID	MPN345
Location	412681 - 413301 +
Sequence	1 ATGAGATGAA GTGACTCTGA AAACAATAAA ATCGACTATA TTGAAGACTT TGCAACTCAT 61 TTTTTAAACA AAAACGCCTT ATTAAACGTT ATTTGTAAAT TTTGTGTGTT CAGGTCAAAT 121 AGTGATCTTT GAGTTATGCG TCCTTACCAA ATATGCGCAA CTGAAAGAAT TTTAGAAAAA 181 ATAAAAGAAG ACAATAGGAA CAGTAAAAAC TCTAAAAATG CAAGTAAGGG CGGCTGTATT 241 TGACACTCAA CCGGAAGTGG TAAAACACTA ACTTCTTTTA AAGCTGTTCA ATTGGCTAGT 301 GAAATAGACT TTGTTGATAA AGTCCTTTTC GTTGTTGACA GGAAAGACTT GGACAACCAA 361 ACGATCGAAG AATATGAAAA GTTTCAAGCG GGTTCTGTTA GCGAAACTGA GAACACAAAT 421 GATCTTAAAG AAAAGATATT AGACGATAGT ACCGCCACAC GTGCAATTGT TACTACTATT 481 CATAAACTTA AGAGGTTAAT AGATCAGAGA AGTAAGCTTA AAGACGAAGA TCTTAAAAAG 541 AAAAACATCG TTCTTATATT CGATGAATGT CATCGATCTC AATTTGGAAA AATGAAACAA 601 GAAATCGATG AGTTTTTTTA A
Download Sequence
Operon	OP136
Operon location	412542 - 413750

Name	Putative type-1 restriction enzyme mpnORFDP R protein part 2 (EC 3.1.21.3) (Putative type I restriction enzyme mpnORFDP R protein part 2) (mpnORFDBP)
Stable ID	Mpn345
Molecular Weight	22660
Isoelectric Point	7
Localization	Cytoplasm
Comment	Fragment. Subunit R is required for both nuclease and ATPase activities, but not for modification
Sequence	MRWSDSENNKIDYIEDFATHFLNKNALLNVICKFCVFRSNSDLWVMRPYQICATERILEKIKEDNRNSKNSKNASKGGCI WHSTGSGKTLTSFKAVQLASEIDFVDKVLFVVDRKDLDNQTIEEYEKFQAGSVSETENTNDLKEKILDDSTATRAIVTTI HKLKRLIDQRSKLKDEDLKKKNIVLIFDECHRSQFGKMKQEIDEFF

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
45	193	148	- MCJ_004080	Mycoplasma conjunctivae	301	445	0.00000002	28.481	119
3	198	195	- MHO_5240	Mycoplasma hominis	242	433	<1e-50	45.4082	458
21	206	185	-	Mycoplasma pulmonis	219	410	6e-26	34.359	270
21	205	184	-	Mycoplasma pulmonis	219	409	1e-26	35.0515	276
2	206	204	- MMOB2830	Mycoplasma mobile	106	302	<1e-50	48.2927	489
1	202	201	- LIC_10929	Leptospira interrogans serovar Copenhage	227	422	<1e-50	48.7685	471
1	206	205	- MYCGA6850	Mycoplasma gallisepticum	224	440	1e-26	34.9776	276
21	205	184	-	Mycoplasma pulmonis	219	409	1e-26	35.0515	276
21	205	184	-	Mycoplasma pulmonis	219	409	1e-26	35.0515	277

COG	COG0610V
EC number	3.1.21.3
Gene ID	877166
GI	13508084
GO	Defense mechanisms
Home COG	V
InterPro	IPR014001\|DEAD-like helicases, N-terminal
InterPro	IPR006935\|Type III restriction enzyme, res subunit
Old MP number	MP491
Pathway	DNA maintenance and repair
PDB homologs	1d9z_A
PDB homologs	1d2m_A
PDB homologs	1d9x_A
Pfam	PF00270
Pfam	PF04851
PID	g1674183
RefSeq	NP_110033.1
Swiss-Prot protein ID	T1RY_MYCPN
phylomeDB tree	No orthologous found
UniProt	P75433