MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene dhfr (MPN321)
Name 
dhfr
Stable ID 
MPN321
Location 
381529 - 382011 +
Sequence 
    1  ATGGTAAAAG CAATTTGAGC AATGGATCAA AATGGGTTAA TTGGTAACGG TAACAGTTTG
   61  CCCTGAAGGA TTAAAGCGGA GTTACAGCAC TTTCGCCAGA CCACGTTGCA CCAAGATGTA
  121  TTAATGGGCT CGGCTACCTA TCTTTCCTTA CCGCCGGTGT TTAGTGAGCG TAACGTTTAT
  181  ATCCTCACCC GTAACCTCAA CTTTAACCCG CCTGATAAGG GCTGTTTGAC TAAAGTAATC
  241  CATGAATATG AAAACTTTAT CCAACCTTAT TTGCACCATC CCGATAAACA CCTCTACATC
  301  TGTGGTGGGG CACAAGTTTA TGAACAGCTC ATTCCCCGGT GTGATGCGTT AATTGTCTCT
  361  ACCATTTTCG GTAAATACAC CGGGGACAAA TACCTCAAAG TGGATTTTAG TCCCTTTGAA
  421  TTGACCAAAG AGATCAGTTT TGCTGAGTTT AAGGTCGCTT ACTATCACAA AATTGCACGA
  481  TAA
Download Sequence
Operon 
OP127
Operon location 
380638 - 385680
Protein (mpn321)
Name 
Dihydrofolate reductase (EC 1.5.1.3)
Stable ID 
Mpn321
Molecular Weight 
17600
Isoelectric Point 
8
Localization 
Cytoplasm
Comment -
Sequence 
MVKAIWAMDQNGLIGNGNSLPWRIKAELQHFRQTTLHQDVLMGSATYLSLPPVFSERNVYILTRNLNFNPPDKGCLTKVI
HEYENFIQPYLHHPDKHLYICGGAQVYEQLIPRCDALIVSTIFGKYTGDKYLKVDFSPFELTKEISFAEFKVAYYHKIAR


















Post translational modifications






No post translational modifications were found 















GENE/PROTEIN dhfr (Domains Overview)






Click on the features to jump to domain info


















 ExportIMG		














Domains (InterProScan)






Location (aa)
Name (InterPro ID)
Description
GO terms
Sequence
Evalue




1-148
PF00186 (IPR001796)
Dihydrofolate reductase domain
Biological Process:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006545'>'glycine' == '' ? '': 'glycine'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006545)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009165'>'nucleotide' == '' ? '': 'nucleotide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009165)



Molecular Function:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004146'>'dihydrofolate' == '' ? '': 'dihydrofolate'; 'reductase' == '' ? '': 'reductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004146)





1.9e-33




1-158
G3DSA:3.40.430.10 (n.a.)
NULL


9.2e-39




1-158
SSF53597 (n.a.)
NULL


1.19951e-42




1-160
PS51330 (IPR001796)
Dihydrofolate reductase domain
Biological Process:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006545'>'glycine' == '' ? '': 'glycine'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006545)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009165'>'nucleotide' == '' ? '': 'nucleotide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009165)



Molecular Function:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004146'>'dihydrofolate' == '' ? '': 'dihydrofolate'; 'reductase' == '' ? '': 'reductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004146)





0




13-23
PR00070 (IPR012259)
Dihydrofolate reductase
Biological Process:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006545'>'glycine' == '' ? '': 'glycine'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006545)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009165'>'nucleotide' == '' ? '': 'nucleotide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009165)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0055114'>'oxidation' == '' ? '': 'oxidation'; 'reduction' == '' ? '': 'reduction'; ('GO' == '' ? '': 'GO';:0055114)



Molecular Function:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004146'>'dihydrofolate' == '' ? '': 'dihydrofolate'; 'reductase' == '' ? '': 'reductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004146)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0050661'>'NADP' == '' ? '': 'NADP'; 'or' == '' ? '': 'or'; 'NADPH' == '' ? '': 'NADPH'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0050661)





0.0000000000017




13-35
PS00075 (IPR017925)
Dihydrofolate reductase conserved site


0




13-129
PTHR11549 (n.a.)
NULL


3.80001e-25




13-129
PTHR11549:SF1 (IPR012259)
Dihydrofolate reductase
Biological Process:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006545'>'glycine' == '' ? '': 'glycine'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006545)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009165'>'nucleotide' == '' ? '': 'nucleotide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009165)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0055114'>'oxidation' == '' ? '': 'oxidation'; 'reduction' == '' ? '': 'reduction'; ('GO' == '' ? '': 'GO';:0055114)



Molecular Function:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004146'>'dihydrofolate' == '' ? '': 'dihydrofolate'; 'reductase' == '' ? '': 'reductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004146)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0050661'>'NADP' == '' ? '': 'NADP'; 'or' == '' ? '': 'or'; 'NADPH' == '' ? '': 'NADPH'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0050661)





3.80001e-25




27-35
PR00070 (IPR012259)
Dihydrofolate reductase
Biological Process:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006545'>'glycine' == '' ? '': 'glycine'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006545)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009165'>'nucleotide' == '' ? '': 'nucleotide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009165)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0055114'>'oxidation' == '' ? '': 'oxidation'; 'reduction' == '' ? '': 'reduction'; ('GO' == '' ? '': 'GO';:0055114)



Molecular Function:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004146'>'dihydrofolate' == '' ? '': 'dihydrofolate'; 'reductase' == '' ? '': 'reductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004146)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0050661'>'NADP' == '' ? '': 'NADP'; 'or' == '' ? '': 'or'; 'NADPH' == '' ? '': 'NADPH'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0050661)





0.0000000000017




40-51
PR00070 (IPR012259)
Dihydrofolate reductase
Biological Process:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006545'>'glycine' == '' ? '': 'glycine'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006545)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009165'>'nucleotide' == '' ? '': 'nucleotide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009165)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0055114'>'oxidation' == '' ? '': 'oxidation'; 'reduction' == '' ? '': 'reduction'; ('GO' == '' ? '': 'GO';:0055114)



Molecular Function:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004146'>'dihydrofolate' == '' ? '': 'dihydrofolate'; 'reductase' == '' ? '': 'reductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004146)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0050661'>'NADP' == '' ? '': 'NADP'; 'or' == '' ? '': 'or'; 'NADPH' == '' ? '': 'NADPH'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0050661)





0.0000000000017




97-111
PR00070 (IPR012259)
Dihydrofolate reductase
Biological Process:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006545'>'glycine' == '' ? '': 'glycine'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006545)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009165'>'nucleotide' == '' ? '': 'nucleotide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009165)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0055114'>'oxidation' == '' ? '': 'oxidation'; 'reduction' == '' ? '': 'reduction'; ('GO' == '' ? '': 'GO';:0055114)



Molecular Function:

<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004146'>'dihydrofolate' == '' ? '': 'dihydrofolate'; 'reductase' == '' ? '': 'reductase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004146)
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0050661'>'NADP' == '' ? '': 'NADP'; 'or' == '' ? '': 'or'; 'NADPH' == '' ? '': 'NADPH'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0050661)





0.0000000000017












Protein Homology (BLASTP results)






Protein Start
Protein End
Hit Size
Orthologous
Organism
Orthologous Start
Orthologous End
Evalue
Identity
Score
Alignment




7
129
122
 - 
Caulobacter crescentus NA1000
11
134
0.000000000001
27.2
158





1
144
143
 - 
Lactococcus lactis subsp. lactis KF147
1
144
2e-19
33.3333
216





1
132
131
 - 
Bacillus subtilis subsp. subtilis
1
126
0.000000000001
28.8889
162





1
132
131
 - 
Bacillus subtilis subsp. subtilis
1
126
0.000000000001
28.5714
161





1
157
156
 - Rv2763c
Mycobacterium tuberculosis
1
158
0.00000000000002
30.1775
175





1
153
152
 - b0048
Escherichia coli
1
143
0.00000000008
28.7582
144





1
157
156
 - MG228
Mycoplasma genitalium
1
157
<1e-50
52.2293
441





1
157
156
 - MS53_0397
Mycoplasma synoviae
1
154
2e-27
36.3057
281





1
157
156
 - MMOB0350
Mycoplasma mobile
1
153
6e-21
33.5404
225





1
157
156
 - MYCGA4030
Mycoplasma gallisepticum
1
153
5e-18
27.3885
201





1
157
156
 - MYCGA0470
Mycoplasma gallisepticum
1
154
1e-22
33.9623
241





1
158
157
 - MYPE6860
Mycoplasma penetrans
1
154
3e-20
30
221





1
157
156
 - 
Mycoplasma pulmonis
17
172
3e-37
45
367















External IDs






COG

COG0262H






EC number

1.5.1.3






Gene ID

876943






GI

13508060






GO

Nucleotide transport and metabolism/ Coenzyme metabolism






Home COG

FH






InterPro

IPR012259|Dihydrofolate reductase






InterPro

IPR001796|Dihydrofolate reductase region






Old MP number

MP515






Pathway

Biosynthesis of cofactors, prosthetic groups and carrier






Pathway

Folic acid






Pathway

Metabolism






PDB homologs

1dds_A






PDB homologs

1ddr_A






PDB homologs

1tdr_A






Pfam

PF00186






PID

g1674209






RefSeq

NP_110009.1






Swiss-Prot protein ID

DYR_MYCPN






phylomeDB tree

DYR_MYCPN






UniProt

P78028
















Transcription

























IMAGE BROWSERS






OPERON OP127 (Genomic Overview)






Region:380638-385680


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STRING of Mpn321STRING legend









PDB image(s)



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