MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene orf6 (MPN142)
Name 
orf6
Stable ID 
MPN142
Location 
185747 - 189403 +
Sequence 
    1  ATGAAATCGA AGCTAAAGTT AAAACGTTAT TTACTGTTTT TACCACTTTT ACCGCTAGGG
   61  ACGTTGTCAC TAGCCAACAC CTACCTCCTC CAAGACCACA ACACCCTCAC CCCCTACACG
  121  CCCTTTACGA CACCGCTCAA TGGGGGGCTG GATGTCGTGC GCGCCGCCCA TTTACACCCC
  181  TCATACGAAC TCGTGGACTG AAAGCGGGTG GGGGATACCA AGTTGGTGGC GCTGGTCCGC
  241  TCAGCGTTGG TCAGGGTGAA ATTCCAGGAC ACAACGAGTT CGGATCAAAG TAATACCAAC
  301  CAAAATGCCT TGAGTTTTGA TACCCAAGAA TCACAGAAGG CACTTAATGG CTCGCAGAGT
  361  GGATCTTCTG ACACTTCCGG GTCTAACTCC CAAGACTTCG CCAGCTATGT CCTCATCTTT
  421  AAAGCCGCGC CCAGGGCCAC GTGGGTGTTT GAACGCAAGA TTAAGTTGGC GTTGCCCTAC
  481  GTTAAGCAGG AAAGTCAGGG TTCCGGCGAT CAAGGTTCCA ATGGTAAGGG CTCCCTCTAC
  541  AAAACCCTCC AAGACCTCCT CGTCGAACAA CCCGTGACCC CTTACACCCC GAATGCGGGG
  601  TTAGCCCGGG TGAATGGGGT TGCTCAGGAT ACGGTTCATT TTGGTTCGGG TCAAGAATCG
  661  AGTTGGAATT CCCAACGTTC CCAAAAAGGC CTTAAAAACA ACCCCGGACC CAAAGCCGTC
  721  ACCGGCTTTA AGCTCGATAA GGGCCGCGCG TACCGGAAGC TGAATGAAAG TTGACCGGTG
  781  TATGAACCCC TGGATTCGAC CAAGGAGGGG AAGGGGAAGG ATGAGAGCTC TTGGAAAAAT
  841  TCGGAAAAAA CAACAGCGGA AAATGATGCC CCGTTGGTGG GGATGGTTGG AAGTGGTGCG
  901  GCTGGAAGTG CTTCTAGTTT ACAAGGCAAT GGCTCGAACA GTTCGGGGTT AAAATCGCTC
  961  TTGAGATCAG CACCTGTCAG TGTTCCACCA AGCAGTACAA GTAATCAAAC TTTAAGCTTA
 1021  TCTAACCCCG CTCCTGTGGG CCCACAAGCG GTTGTAAGCC AACCCGCGGG GGGTGCTACG
 1081  GCAGCAGTGT CCGTCAATCG CACAGCGAGT GACACCGCCA CCTTTAGCAA GTACCTCAAC
 1141  ACCGCCCAGG CCTTGCACCA GATGGGGGTG ATTGTTCCGG GGTTGGAAAA ATGAGGTGGT
 1201  AACAACGGTA CGGGTGTAGT GGCTAGCCGA CAGGATGCTA CTTCCACTAA CCTGCCCCAT
 1261  GCGGCAGGTG CTTCCCAAAC GGGTTTGGGA ACTGGTTCGC CCCGCGAACC AGCTTTAACC
 1321  GCAACGTCAC AGCGTGCCGT CACGGTGGTT GCTGGCCCCC TTCGTGCGGG CAATAGCAGT
 1381  GAAACTGATG CCCTACCGAA TGTCATCACC CAGCTCTATC ATACTTCAAC CGCCCAACTC
 1441  GCTTACTTAA ATGGCCAGAT CGTTGTGATG GGTTCCGACC GGGTACCGAG TCTTTGGTAT
 1501  TGAGTTGTCG GGGAGGACCA GGAATCGGGC AAAGCGACCT GATGAGCGAA AACCGAGCTC
 1561  AACTGGGGCA CCGACAAGCA GAAGCAGTTT GTCGAAAACC AGTTGGGGTT TAAAGATGAC
 1621  TCAAATTCGG ATTCCAAAAA TTCGAATTTG AAGGCCCAAG GCCTCACCCA ACCCGCCTAC
 1681  CTCATCGCCG GTCTTGACGT TGTGGCCGAC CACCTCGTCT TTGCGGCCTT TAAAGCGGGC
 1741  GCGGTGGGGT ATGATATGAC GACTGATTCG AGCGCTTCGA CCTACAACCA AGCACTCGCC
 1801  TGGTCGACCA CGGCCGGGTT GGACAGTGAT GGGGGGTACA AGGCCTTGGT GGAAAACACG
 1861  GCCGGGCTCA ACGGCCCGAT TAATGGCTTG TTTACCCTGC TCGACACCTT TGCGTATGTG
 1921  ACCCCCGTGA GTGGGATGAA AGGGGGGAGT CAGAATAATG AAGAAGTGCA AACGACTTAC
 1981  CCGGTCAAGT CCGACCAAAA GGCCACCGCC AAAATTGCCT CCTTAATTAA TGCCAGCCCA
 2041  CTCAACAGTT ATGGGGATGA TGGGGTGACC GTGTTTGATG CCCTGGGCCT TAACTTTAAC
 2101  TTTAAGTTGA ACGAGGAGCG CTTGCCATCG CGCACCGACC AACTGCTTGT GTATGGGATT
 2161  GTAAACGAAA GTGAACTGAA GTCCGCACGG GAAAATGCCC AGTCGACCTC CGATGATAAT
 2221  TCAAACACCA AAGTCAAGTG AACCAACACC GCCTCGCACT ACCTCCCCGT GCCGTATTAC
 2281  TACAGTGCCA ATTTCCCCGA AGCGGGTAAC AGAAGGCGAG CGGAGCAGCG GAATGGGGTG
 2341  AAGATTAGCA CCTTGGAATC GCAAGCCACT GATGGCTTTG CCAACTCGTT ACTTAACTTT
 2401  GGTACCGGTC TTAAAGCCGG TGTTGACCCA GCTCCAGTAG CACGGGGTCA TAAACCGAAC
 2461  TATAGTGCAG TACTACTAGT GCGTGGTGGC GTTGTAAGGT TAAACTTTAA CCCCGATACT
 2521  GATAAACTGT TGGATTCTAC TGACAAAAAC AGTGAACCTA TCTCCTTCTC CTATACCCCA
 2581  TTTGGGTCTG CTGAAAGTGC CGTAGACCTC ACCACGTTGA AGGATGTGAC CTATATTGCT
 2641  GAAAGTGGTC TGTGGTTCTA TACCTTTGAC AATGGTGAAA AACCAACGTA CGATGGTAAA
 2701  CAACAACAGG TCAAAAACCG CAAGGGTTAT GCTGTGATTA CCGTATCACG TACCGGAATT
 2761  GAATTTAACG AGGACGCTAA TACCACAACC TTAAGCCAAG CCCCAGCTGC TTTGGCTGTC
 2821  CAAAACGGGA TTGCTTCCAG TCAGGACGAC CTCACAGGCA TCCTACCGTT ATCCGATGAG
 2881  TTCTCCGCTG TGATTACCAA GGATCAAACA TGGACCGGTA AGGTTGATAT CTATAAGAAC
 2941  ACCAACGGGT TGTTTGAAAA GGATGATCAG CTATCGGAAA ACGTGAAGAG GCGTGACAAC
 3001  GGTTTGGTCC CTATTTACAA CGAAGGTATC GTCGATATTT GGGGCAGAGT GGATTTTGCT
 3061  GCCAACAGTG TTTTGCAAGC GCGTAACCTC ACTGATAAAA CGGTTGATGA GGTGATCAAT
 3121  AACCCCGATA TCCTCCAAAG CTTCTTTAAG TTTACCCCAG CCTTTGATAA CCAAAGAGCA
 3181  ATGCTAGTGG GGGAAAAGAC ATCGGATACT ACCTTAACGG TTAAACCGAA GATTGAGTAC
 3241  TTGGATGGTA ACTTCTATGG TGAGGATTCC AAGATTGCTG GAATTCCGCT CAACATTGAT
 3301  TTCCCTTCCC GGATTTTTGC TGGCTTTGCT GCTTTACCGT CCTGGGTCAT TCCGGTATCA
 3361  GTCGGTTCAT CGGTGGGCAT TCTCTTAATC CTGCTCATCT TAGGCCTTGG TATTGGAATT
 3421  CCAATGTATA AGGTCCGCAA GCTTCAAGAC TCCAGCTTTG TTGATGTGTT TAAAAAGGTG
 3481  GATACGTTGA CAACCGCTGT GGGTAGCGTG TACAAGAAGA TTATCACCCA AACGAGTGTG
 3541  ATCAAAAAAG CTCCTAGTGC GTTGAAAGCT GCTAATAACG CTGCTCCTAA AGCACCAGTT
 3601  AAACCAGCTG CTCCAACAGC TCCAAGACCA CCAGTCCAAC CACCTAAAAA GGCTTAA
Download Sequence
Operon 
OP65
Operon location 
179860 - 190300
Protein (mpn142)
Name 
Mgp-operon protein 3 (Mgp3) (ORF-3 protein)
Stable ID 
Mpn142
Molecular Weight 
133980
Isoelectric Point 
9
Localization 
TMHMM
Comment Approximately 4% of the limited M. genitalium genome contains repeat sequences termed MgPar regions that have homology to mgpB and mgpC, which encode antigenic proteins associated with attachment. We have previously shown that mgpB sequences vary within a single strain of M. genitalium in a pattern consistent with recombination between mgpB and MgPar sequences (Iverson-Cabral et al.). In the current study, we show that mgpC heterogeneity similarly occurs within the type strain, G-37T, cultured in vitro and among cervical specimens collected from a persistently infected woman. In all cases, alternative mgpC sequences are indicative of recombination with MgPar regions
Sequence 
MKSKLKLKRYLLFLPLLPLGTLSLANTYLLQDHNTLTPYTPFTTPLNGGLDVVRAAHLHPSYELVDWKRVGDTKLVALVR
SALVRVKFQDTTSSDQSNTNQNALSFDTQESQKALNGSQSGSSDTSGSNSQDFASYVLIFKAAPRATWVFERKIKLALPY
VKQESQGSGDQGSNGKGSLYKTLQDLLVEQPVTPYTPNAGLARVNGVAQDTVHFGSGQESSWNSQRSQKGLKNNPGPKAV
TGFKLDKGRAYRKLNESWPVYEPLDSTKEGKGKDESSWKNSEKTTAENDAPLVGMVGSGAAGSASSLQGNGSNSSGLKSL
LRSAPVSVPPSSTSNQTLSLSNPAPVGPQAVVSQPAGGATAAVSVNRTASDTATFSKYLNTAQALHQMGVIVPGLEKWGG
NNGTGVVASRQDATSTNLPHAAGASQTGLGTGSPREPALTATSQRAVTVVAGPLRAGNSSETDALPNVITQLYHTSTAQL
AYLNGQIVVMGSDRVPSLWYWVVGEDQESGKATWWAKTELNWGTDKQKQFVENQLGFKDDSNSDSKNSNLKAQGLTQPAY
LIAGLDVVADHLVFAAFKAGAVGYDMTTDSSASTYNQALAWSTTAGLDSDGGYKALVENTAGLNGPINGLFTLLDTFAYV
TPVSGMKGGSQNNEEVQTTYPVKSDQKATAKIASLINASPLNSYGDDGVTVFDALGLNFNFKLNEERLPSRTDQLLVYGI
VNESELKSARENAQSTSDDNSNTKVKWTNTASHYLPVPYYYSANFPEAGNRRRAEQRNGVKISTLESQATDGFANSLLNF
GTGLKAGVDPAPVARGHKPNYSAVLLVRGGVVRLNFNPDTDKLLDSTDKNSEPISFSYTPFGSAESAVDLTTLKDVTYIA
ESGLWFYTFDNGEKPTYDGKQQQVKNRKGYAVITVSRTGIEFNEDANTTTLSQAPAALAVQNGIASSQDDLTGILPLSDE
FSAVITKDQTWTGKVDIYKNTNGLFEKDDQLSENVKRRDNGLVPIYNEGIVDIWGRVDFAANSVLQARNLTDKTVDEVIN
NPDILQSFFKFTPAFDNQRAMLVGEKTSDTTLTVKPKIEYLDGNFYGEDSKIAGIPLNIDFPSRIFAGFAALPSWVIPVS
VGSSVGILLILLILGLGIGIPMYKVRKLQDSSFVDVFKKVDTLTTAVGSVYKKIITQTSVIKKAPSALKAANNAAPKAPV
KPAAPTAPRPPVQPPKKA
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Methylation AAHLHPSYELVDWkR 55 70 K
Oxidation YLNTAQALHQmGVIVPGLEk 378 398 M
Oxidation YLNTAQALHQmGVIVPGLEK 378 398 M
Oxidation AmLVGEK 1060 1067 M
Oxidation AmLVGEKTSDTTLTVKPK 1060 1078 M
GENE/PROTEIN orf6 (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
360-406 PD008387 (n.a.) NULL 0
490-715 PF05220 (IPR007885) MgpC 0
1114-1214 PF07271 (IPR009896) Cytadhesin P30P32 Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0007157'>'heterophilic' == '' ? '': 'heterophilic'; 'cell' == '' ? '': 'cell';-'cell' == '' ? '': 'cell'; 'adhesion' == '' ? '': 'adhesion'; ('GO' == '' ? '': 'GO';:0007157) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009405'>'pathogenesis' == '' ? '': 'pathogenesis'; ('GO' == '' ? '': 'GO';:0009405)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016021'>'integral' == '' ? '': 'integral'; 'to' == '' ? '': 'to'; 'membrane' == '' ? '': 'membrane'; ('GO' == '' ? '': 'GO';:0016021)

0.12
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
467 1181 714 - MG192 Mycoplasma genitalium 289 1005 <1e-50 59.116 2133
51 293 242 - MG192 Mycoplasma genitalium 53 255 1e-36 36.5854 2133
1013 1177 164 - MYCGA1830 Mycoplasma gallisepticum 590 750 0.000000006 24.2424 132
1012 1179 167 - MYCGA1810 Mycoplasma gallisepticum 830 994 6e-22 36.8421 244
1045 1180 135 - MYCGA1800 Mycoplasma gallisepticum 927 1061 0.000000003 32.3944 134
External IDs
Gene ID 
877207
GI 
13507881
GO 
Cell envelope biogenesis, outer membrane
Home COG 
M
InterPro 
Approximately 4% of the limited M. genitalium genome contains repeat sequences termed MgPar regions that have homology to mgpB and mgpC, which encode antigenic proteins associated with attachment. We have previously shown that mgpB sequences vary within a
Old MP number 
MP012
Pathway 
Adhesion
Pfam 
PF08372
Pfam 
PF05220
PID 
g1673658
RefSeq 
NP_109830.1
Swiss-Prot protein ID 
MGP3_MYCPN/B2BDZ7_MYCPN
phylomeDB tree No orthologous found
UniProt 
Q50341/B2BDZ7
Transcription
IMAGE BROWSERS

OPERON OP65 (Genomic Overview)
Region:179860-190300

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STRING image

STRING of Mpn142STRING legend

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