MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene hrcA (MPN124)
Name 
hrcA
Stable ID 
MPN124
Location 
160730 - 161785 -
Sequence 
    1  ATGAAAAATT TAACTACCCG ACAAGCCCAA ATTCTCAAGG CCATCATCAA CGAATATATT
   61  GCCTATCCAG TACCTGTTGG TAGTAAATTA TTAACTAAAA AATATTTTAA AAACCTCTCT
  121  GGCGGTACAC TCCGAAACGA AATGGCCGTT TTGGAAAAAG AGGGTTATCT CAAAAAGAAC
  181  CACATCTCTT CAGGGCGAAT CCCCTCCCAG TTGGGCTATC AGTACTATGT CAAGTTACTC
  241  ACTAAAAATG ATGATAAGAG TAACCTTAAA ACCCGCTTAA GGGCGATTAT CTTGCAAAAA
  301  CACAAAACAA TTGATGAAAT TATTGAACTG GGGGTAAAGT TTATCAACGA AATGGTAAAC
  361  CTACCAGTGG TGTTAACCCA CTTTAGTAGT GATGAAGTCT TAAAAAAGAT TGATCTCATT
  421  ATGCTCGATC AGTCCTGTGC ACTGCTACTG TTAGTGTCAG CTAGTGGTAA CGTCTTTAAG
  481  AAAACGATTA GCTATGCTAA CCAAAGACAG TTTGAAGACA TCATGGTATG TGTCAGGATC
  541  TTTAATGATC GCATTATCGA TACACGTTTC TGTGATATTG CCCAACACTT AGATGTTTTA
  601  AAGGAAATTA TTCGCAGCAA GGTACACGAG TACCAGTATG TCATTGACGA AATCCTGTTT
  661  AAGCTGTTTA ACTTTGAGGA ATTCCAACAA GCACGTAAGC AGGTTTATGG CATCCATTAC
  721  CTAGCCCAAC AACCAGAGTT TGCCAACCAG GAAAGATTGA CGCGTATCTT AAACTTACTG
  781  GAAGATACTA GTGTCTGACA ACAAATGGCC TTTATGAACC AAAACAACCA GACTACTAAT
  841  ATTACGTTTG GTGACAAGTT AGGATTAGAA GGGGAAGAGG TTTCGGTAGC TTCTACTCTT
  901  ATTAATACCA CCAACGAAAG TAAGCACCAA CTAGCGATAG TGGGTCCCAC CCGGATGGAC
  961  TACCAAAAGG TGAAAGCGTT ATTGTTGACC CTCAAAGAAG AGATCGAGGA GTACGATAAG
 1021  CAACTTCACG GTGGTAAAAC CACTAGCTCC ACTTAA
Download Sequence
Operon 
OP531
Operon location 
160080 - 161800
Protein (mpn124)
Name 
Heat-inducible transcription repressor hrcA
Stable ID 
Mpn124
Molecular Weight 
38610
Isoelectric Point 
9
Localization 
Cytoplasm
Comment -
Sequence 
MKNLTTRQAQILKAIINEYIAYPVPVGSKLLTKKYFKNLSGGTLRNEMAVLEKEGYLKKNHISSGRIPSQLGYQYYVKLL
TKNDDKSNLKTRLRAIILQKHKTIDEIIELGVKFINEMVNLPVVLTHFSSDEVLKKIDLIMLDQSCALLLLVSASGNVFK
KTISYANQRQFEDIMVCVRIFNDRIIDTRFCDIAQHLDVLKEIIRSKVHEYQYVIDEILFKLFNFEEFQQARKQVYGIHY
LAQQPEFANQERLTRILNLLEDTSVWQQMAFMNQNNQTTNITFGDKLGLEGEEVSVASTLINTTNESKHQLAIVGPTRMD
YQKVKALLLTLKEEIEEYDKQLHGGKTTSST
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation mKNLTTR 1 8 M
Oxidation NLSGGTLRNEmAVLEK 38 54 M
Oxidation NEmAVLEK 46 54 M
Oxidation FINEmVNLPVVLTHFSSDEVLK 114 136 M
GENE/PROTEIN hrcA (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-343 PIRSF005485 (IPR002571) Winged helix-turn-helix transcription repressor, H Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:'of' == '' ? '': 'of';'>'regulation' == '' ? '': 'regulation'; 'of' == '' ? '': 'of'; 'transcription' == '' ? '': 'transcription';

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677)

0
2-84 G3DSA:1.10.10.10 (IPR011991) Winged helix-turn-helix transcription repressor DN 1.7e-29
3-89 SSF46785 (n.a.) NULL 2.2e-19
5-339 TIGR00331 (IPR002571) Winged helix-turn-helix transcription repressor, H Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:'of' == '' ? '': 'of';'>'regulation' == '' ? '': 'regulation'; 'of' == '' ? '': 'of'; 'transcription' == '' ? '': 'transcription';

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677)

0
73-343 SSF55781 (n.a.) NULL 2.2e-27
104-324 PF01628 (IPR021153) Winged helix-turn-helix transcription repressor, H Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:'of' == '' ? '': 'of';'>'regulation' == '' ? '': 'regulation'; 'of' == '' ? '': 'of'; 'transcription' == '' ? '': 'transcription';

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677)

3.4e-34
178-338 G3DSA:3.30.450.40 (n.a.) NULL 0.0000000000000017
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
4 340 336 - MAG5590 Mycoplasma agalactiae 9 335 5e-31 27.3529 316
4 321 317 - MARTH_orf618 Mycoplasma arthritidis 10 319 7e-39 30.625 384
1 328 327 - Caulobacter crescentus NA1000 15 345 0.00000006 18.806 123
1 318 317 - MCJ_001580 Mycoplasma conjunctivae 3 310 5e-37 29.5597 368
15 323 308 - MHO_4090 Mycoplasma hominis 31 330 2e-38 30.3226 378
4 344 340 - Lactococcus lactis subsp. lactis KF147 2 340 1e-18 26.0388 212
1 328 327 - Bacillus subtilis subsp. subtilis 1 328 3e-33 31.3783 344
4 328 324 - Bacillus subtilis subsp. subtilis 2 326 4e-33 31.3609 342
1 344 343 - MG205 Mycoplasma genitalium 1 341 <1e-50 79.6512 1473
3 328 325 - LIC_10526 Leptospira interrogans serovar Copenhage 2 326 1e-19 26.284 223
1 321 320 - Rv2374c Mycobacterium tuberculosis 1 322 8e-21 22.9358 234
4 328 324 - MCAP_0367 Mycoplasma capricolum subsp. capricolum 2 328 1.99993e-41 31.6265 406
1 331 330 - MS53_0353 Mycoplasma synoviae 1 319 1e-27 26.1261 287
1 298 297 - MHP7448_0010 Mycoplasma hyopneumoniae 7448 1 289 1e-34 29.8658 348
7 332 325 - MMOB1110 Mycoplasma mobile 6 320 6.99949e-42 31.7073 409
4 328 324 - MSC_0612 Mycoplasma mycoides subsp. mycoides SC 2 328 1.99993e-41 31.9277 407
4 339 335 - MYCGA3540 Mycoplasma gallisepticum 5 336 <1e-50 49.2582 839
1 337 336 - MYPE710 Mycoplasma penetrans 1 335 <1e-50 40.4692 681
4 344 340 - Mycoplasma pulmonis 10 340 <1e-50 32.9446 467
External IDs
COG 
COG1420K
Gene ID 
877265
GI 
13507863
GO 
Transcription
Home COG 
K
InterPro 
IPR002571|Negative regulator of class I heat shock protein
Old MP number 
MP030
Pathway 
Regulation
Pfam 
PF01726
Pfam 
PF01628
PID 
g1673678
RefSeq 
NP_109812.1
Swiss-Prot protein ID 
HRCA_MYCPN
phylomeDB tree 
HRCA_MYCPN
UniProt 
P75351
Transcription
IMAGE BROWSERS

OPERON OP531 (Genomic Overview)
Region:160080-161800

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STRING image

STRING of Mpn124STRING legend

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