Gene parC (MPN123)
Name
parC
Stable ID
MPN123
Location
158374 - 160743 +
Sequence
    1  ATGGAAAAGA ATAAACAAGC GTTATTACTC CAGGCCATCG AAGATGTCTT TGCCTTTAGC
   61  TTTAGTAAGT ATGCTAAGTA CATTATCCAA GACCGGGCTT TACCTGATCT ACGTGATGGG
  121  CTTAAACCAG TTCAACGCCG CATCCTCTAT GGCATGTACC AAATGGGCTT AAAACCCACT
  181  TCACCCTACA AAAAGTCAGC TCGGGCAGTC GGAGAAATTA TGGGTAAGTA CCACCCCCAT
  241  GGCGATGCAT CGATCTATGA TGCGATTGTA AGGATGTCAC AAGCCTGAAA GAACAACCTC
  301  ACTACTATCT CCATTCACGG GAATAATGGT TCCATAGATG GTGATAACGC TGCCGCGATG
  361  CGCTATACCG AAGCGCGTTT AAGTCCGTAC GGGTTTGAAC TACTCAAAGA CATTGAAAAG
  421  CAGTTAGTAC CGTTTGTGAA TAACTTTGAT GACAGTGAGG TCGAACCGAG CGTGTTACCA
  481  ACCCTGTTAC CTAACCTCTT TATTAACGGT ACCAGTGGAA TAGCGGCGGG TTATGCCACT
  541  AATATTGCAC CCCATAATGT CGGTGAACTG CTTGATGGTT TGAGTTACCG GATTGAAAAC
  601  CCTGATTGTG ATTTAAAGGC CATCTTAAAG ATTGTTAAGG GACCGGATTT TCCAACTGGG
  661  GGATTAGTGT ACTTTGAGCA AGAGTTGGCG AACATCTACC AAACTGGGAA GGGTAAGTTT
  721  GTGATTCAGG CCAAATATGA AACGAACACT GCGTTTGGCC AAAACCAGAT TGTAATCACC
  781  GAAATCCCAT ACGAAACGGT GAAGGCCAAT ATTGTTAAAC AAATTGAAGA GTTAATTAGT
  841  GACAATAAAC TCAGTGCCTT GGAAAGTGTG ATTGACAGCT CTGATCGTAG TGGTATTCGA
  901  ATCATTATTA ACCACAAGGA CTTTTTGAGT GCTGACAAGA TTATGGCGTT CTTGTTCAAA
  961  CACACCCAAC TCCAAGTAAA CTTTAACCTC AACAATACGG TAATTGCCAA CCGTTGTCCG
 1021  GTACGGGTGG GGTTGTTAGC TTACTTTGAT CAGTTCCTAG CCTTTGCCCA CGAATTGATC
 1081  ATTAACAGCG CCAAGTATGA TTTAGCATTG GCCAATAAGC GCTTGGAAAT CATTAAGGGC
 1141  TTAATTAAGG CGGTTTCCAT GATTGATGAA ATTATTCGTT TAATTCGCCG TGCTACTGAC
 1201  AAACAGGATG CGAAAACCAA GCTCATTGAC AAGTATGCTT TTACCCTAAA TCAAGCCGAA
 1261  GCGATTGTGT CGTTGCGTTT GTACCAGTTA ACTAACACCG ACATTAAGGT CCTGTTTGCC
 1321  GAACAAAAAG AGTTAGAGCA AACGATCCAA ACAGCCGAAC GCTTAATTGC TAAACCGCAA
 1381  GCACGAAACC AGTTGTTACA AGCACAGTTT TTCCAATACA AAAAGCAGTT TAACCAACCA
 1441  CGACGCGCAC AAATAGTTGG TTTAATTGAA AAGCAAAAGG TACAAGACAG TGACTTCATC
 1501  GAACACAAGG AAGTGGGCTT ACTCATTAGT CACGATGGCA TCTACTTTAA GTTTGAACCA
 1561  GAACAGTTAG CGAAGCACCT AGTGGAATTT AAAAGTGAAC AAGACCAACT GATTTTTGGA
 1621  GGCGTAGTAC AAAACTCCGA TTACTTTTTT ATGGTGACTT CACTCGGTAA CATTATTACC
 1681  GTTCCCATTT ACAAAACGTT AAGTAACACC AAAACCAAGA TGAACGAGTT GTTGGCCAAA
 1741  AAACCGATCC TAATGGAAGA TGAAAAATTG GTACTAGCAG GGATTGTAAA CCCAGACAAA
 1801  ATGGAACAAC AGCTCTTGGT GTTAACGTCA CAGTGCGGTA TGGTCAAACG GGTCGAGTTG
 1861  AGCAAAGTCA TTAACACGAA GCAAATTAAG TCAAGCTGCT GCATGGCACT CCGGGAACGC
 1921  GACAAACTGG TCAACGCCTT TGTTCAAACT AAAGGGGAAC CTAAACTAGT TTGTCTGGTG
 1981  TCATCTTCCA ACAGTTTTGC TACCTTCTTA GCGGAAGAAA TTCCAATTAT TAGTAACAAG
 2041  GGAATTGGGG TGAAGGGGAT TAAACTCAAA GCTGAGGAAA AGGTACGGTT TGCAATGCCG
 2101  TTACAGGATA ATGATGCCTT AGTAGTGATT AACAGTGATG GTGGTGTCTA TAACTTTGAA
 2161  GTAGTGGAAC TGGCAGTCGC TAGCCGCATG AGTGTTGGTA AAAAACTAAT TCCCAAAACC
 2221  AAAACCCCGG TAAGCTGTTT TGCTGCTAAT AAGCACAGTG AGATTATTGG TCATCGTGGT
 2281  AAAAATGGTA GTGATCTGTT TACCCTAAAT GAGTTAAACC GTTTACCAAA GTCAACCGTT
 2341  AGTCAAATGC GTTTGTTTAA GTGGAGCTAG 
Download Sequence
Operon
OP54
Operon location
152540 - 160900
Protein (mpn123)
Name
DNA topoisomerase 4 subunit A (EC 5.99.1.-) (Topoisomerase IV subunit A)
Stable ID
Mpn123
Molecular Weight
86790
Isoelectric Point
9
Localization
Cytoplasm
Comment -
Sequence
MEKNKQALLLQAIEDVFAFSFSKYAKYIIQDRALPDLRDGLKPVQRRILYGMYQMGLKPTSPYKKSARAVGEIMGKYHPH
GDASIYDAIVRMSQAWKNNLTTISIHGNNGSIDGDNAAAMRYTEARLSPYGFELLKDIEKQLVPFVNNFDDSEVEPSVLP
TLLPNLFINGTSGIAAGYATNIAPHNVGELLDGLSYRIENPDCDLKAILKIVKGPDFPTGGLVYFEQELANIYQTGKGKF
VIQAKYETNTAFGQNQIVITEIPYETVKANIVKQIEELISDNKLSALESVIDSSDRSGIRIIINHKDFLSADKIMAFLFK
HTQLQVNFNLNNTVIANRCPVRVGLLAYFDQFLAFAHELIINSAKYDLALANKRLEIIKGLIKAVSMIDEIIRLIRRATD
KQDAKTKLIDKYAFTLNQAEAIVSLRLYQLTNTDIKVLFAEQKELEQTIQTAERLIAKPQARNQLLQAQFFQYKKQFNQP
RRAQIVGLIEKQKVQDSDFIEHKEVGLLISHDGIYFKFEPEQLAKHLVEFKSEQDQLIFGGVVQNSDYFFMVTSLGNIIT
VPIYKTLSNTKTKMNELLAKKPILMEDEKLVLAGIVNPDKMEQQLLVLTSQCGMVKRVELSKVINTKQIKSSCCMALRER
DKLVNAFVQTKGEPKLVCLVSSSNSFATFLAEEIPIISNKGIGVKGIKLKAEEKVRFAMPLQDNDALVVINSDGGVYNFE
VVELAVASRMSVGKKLIPKTKTPVSCFAANKHSEIIGHRGKNGSDLFTLNELNRLPKSTVSQMRLFKWS
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation mEKNKQALLLQAIEDVFAFSFSKYAK 1 27 M
Methylation nkQALLLQAIEDVFAFSFSKYAk 4 27 K
Methylation nkQALLLQAIEDVFAFSFSkYAK 4 27 K
Oxidation ILYGmYQMGLKPTSPYKK 48 66 M
Oxidation AVSmIDEIIR 384 394 M
GENE/PROTEIN parC (Domains Overview)
Click on the features to jump to domain info

 ExportIMG
Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
8-744 TIGR01061 (IPR005741) DNA topoisomerase IV, subunit A, Gram-positive Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003918'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; ('ATP' == '' ? '': 'ATP';-'hydrolyzing' == '' ? '': 'hydrolyzing';) 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003918) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

0
11-463 SM00434 (IPR002205) DNA topoisomerase, type IIA, subunit A/C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003918'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; ('ATP' == '' ? '': 'ATP';-'hydrolyzing' == '' ? '': 'hydrolyzing';) 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003918) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

0
30-235 G3DSA:3.90.199.10 (IPR013758) DNA topoisomerase, type IIA, subunit A/ C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006259'>'DNA' == '' ? '': 'DNA'; 'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006259) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003918'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; ('ATP' == '' ? '': 'ATP';-'hydrolyzing' == '' ? '': 'hydrolyzing';) 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003918) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

0
30-486 SSF56719 (IPR013760) DNA topoisomerase, type IIA, central Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003918'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; ('ATP' == '' ? '': 'ATP';-'hydrolyzing' == '' ? '': 'hydrolyzing';) 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003918) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

0
32-199 PTHR10169 (n.a.) NULL 0.0000000078
32-199 PTHR10169:SF2 (n.a.) NULL 0.0000000078
32-462 PF00521 (IPR002205) DNA topoisomerase, type IIA, subunit A/C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003918'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; ('ATP' == '' ? '': 'ATP';-'hydrolyzing' == '' ? '': 'hydrolyzing';) 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003918) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

0
236-331 G3DSA:3.30.1360.40 (IPR020899) Arginine repressor, C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:'of' == '' ? '': 'of';'>'regulation' == '' ? '': 'regulation'; 'of' == '' ? '': 'of'; 'transcription' == '' ? '': 'transcription';

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003700'>'sequence' == '' ? '': 'sequence';-'specific' == '' ? '': 'specific'; 'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; 'transcription' == '' ? '': 'transcription'; 'factor' == '' ? '': 'factor'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003700)

4.2e-27
332-406 G3DSA:3.90.199.10 (IPR013758) DNA topoisomerase, type IIA, subunit A/ C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006259'>'DNA' == '' ? '': 'DNA'; 'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0006259) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003918'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; ('ATP' == '' ? '': 'ATP';-'hydrolyzing' == '' ? '': 'hydrolyzing';) 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003918) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

0
499-784 SSF101904 (n.a.) NULL 7.2e-30
546-598 PF03989 (IPR006691) DNA gyrase/topoisomerase IV, subunit A, C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003916'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003916) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

4.5
606-648 PF03989 (IPR006691) DNA gyrase/topoisomerase IV, subunit A, C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003916'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003916) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

4.2
660-699 PF03989 (IPR006691) DNA gyrase/topoisomerase IV, subunit A, C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003916'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003916) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

15
705-739 PF03989 (IPR006691) DNA gyrase/topoisomerase IV, subunit A, C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006265'>'DNA' == '' ? '': 'DNA'; 'topological' == '' ? '': 'topological'; 'change' == '' ? '': 'change'; ('GO' == '' ? '': 'GO';:0006265)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005694'>'chromosome' == '' ? '': 'chromosome'; ('GO' == '' ? '': 'GO';:0005694)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003916'>'DNA' == '' ? '': 'DNA'; 'topoisomerase' == '' ? '': 'topoisomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003916) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)

9400
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
82 287 205 - Bacillus subtilis subsp. subtilis 1 207 <1e-50 42.5121 505
82 287 205 - Bacillus subtilis subsp. subtilis 1 207 <1e-50 42.5121 506
82 287 205 - Bacillus subtilis subsp. subtilis 1 207 <1e-50 42.5121 504
82 287 205 - Bacillus subtilis subsp. subtilis 1 207 <1e-50 42.5121 505
82 287 205 - Bacillus subtilis subsp. subtilis 1 207 <1e-50 41.5459 489
82 265 183 - Bacillus subtilis subsp. subtilis 1 185 <1e-50 44.3243 470
82 265 183 - Bacillus subtilis subsp. subtilis 1 185 <1e-50 44.3243 470
82 283 201 - Bacillus subtilis subsp. subtilis 1 203 <1e-50 42.8571 490
56 287 231 - Bacillus subtilis subsp. subtilis 1 233 <1e-50 45.4936 615
56 287 231 - Bacillus subtilis subsp. subtilis 1 233 <1e-50 45.0644 611
56 287 231 - Bacillus subtilis subsp. subtilis 1 233 <1e-50 45.4936 615
37 340 303 - Bacillus subtilis subsp. subtilis 1 305 <1e-50 42.2951 719
8 756 748 - MAG1830 Mycoplasma agalactiae 16 767 <1e-50 35.9788 1151
1 714 713 - MAG5630 Mycoplasma agalactiae 68 787 <1e-50 30.7065 907
46 287 241 - Bacillus subtilis subsp. subtilis 1 243 <1e-50 44.856 625
15 754 739 - MARTH_orf021 Mycoplasma arthritidis 23 779 <1e-50 31.4548 1015
1 695 694 - MARTH_orf662 Mycoplasma arthritidis 64 762 <1e-50 32.2443 932
8 561 553 - Caulobacter crescentus NA1000 18 584 <1e-50 34.5009 813
13 689 676 - Caulobacter crescentus NA1000 22 730 <1e-50 31.9178 913
1 760 759 - MCJ_000540 Mycoplasma conjunctivae 58 825 <1e-50 31.5924 941
1 747 746 - MCJ_005360 Mycoplasma conjunctivae 1 745 <1e-50 34.2629 1135
62 287 225 - Bacillus subtilis subsp. subtilis 6 232 <1e-50 46.2555 608
62 287 225 - Bacillus subtilis subsp. subtilis 6 232 <1e-50 46.2555 609
62 287 225 - Bacillus subtilis subsp. subtilis 6 232 <1e-50 45.815 598
16 689 673 - MHO_4260 Mycoplasma hominis 86 764 <1e-50 33.0904 948
15 689 674 - MHO_5120 Mycoplasma hominis 23 700 <1e-50 35.4227 1041
13 749 736 - Lactococcus lactis subsp. lactis KF147 9 747 <1e-50 35.809 1255
20 741 721 - Lactococcus lactis subsp. lactis KF147 25 749 <1e-50 34.5628 1012
82 269 187 - Bacillus subtilis subsp. subtilis 1 189 <1e-50 44.4444 475
32 331 299 - Bacillus subtilis subsp. subtilis 1 301 <1e-50 44.186 748
32 331 299 - Bacillus subtilis subsp. subtilis 1 301 <1e-50 44.186 748
49 326 277 - Bacillus subtilis subsp. subtilis 1 279 <1e-50 41.5771 646
114 331 217 - Bacillus subtilis subsp. subtilis 2 220 2.8026e-45 36.9863 450
32 331 299 - Bacillus subtilis subsp. subtilis 3 303 <1e-50 44.186 748
34 331 297 - Bacillus subtilis subsp. subtilis 1 299 <1e-50 43.8127 737
33 331 298 - Bacillus subtilis subsp. subtilis 1 300 <1e-50 44 741
13 733 720 - Bacillus subtilis subsp. subtilis 12 732 <1e-50 38.7052 1277
20 715 695 - Bacillus subtilis subsp. subtilis 21 718 <1e-50 32.7247 982
13 733 720 - Bacillus subtilis subsp. subtilis 12 732 <1e-50 38.7052 1276
13 733 720 - b2231 Escherichia coli 13 770 <1e-50 30.5592 917
12 513 501 - b3019 Escherichia coli 9 508 <1e-50 32.9412 729
20 714 694 - MG004 Mycoplasma genitalium 32 727 <1e-50 31.4448 911
1 787 786 - MG204 Mycoplasma genitalium 1 779 <1e-50 63.7865 2634
4 786 782 - MYCGA7230 Mycoplasma gallisepticum 14 815 <1e-50 31.1138 910
13 733 720 - Rv0006 Mycobacterium tuberculosis 20 749 <1e-50 31.7997 922
4 709 705 - MCAP_0456 Mycoplasma capricolum subsp. capricolum 3 704 <1e-50 39.972 1325
28 771 743 - MCAP_0040 Mycoplasma capricolum subsp. capricolum 3 720 <1e-50 31.2336 889
6 748 742 - MS53_0317 Mycoplasma synoviae 62 810 <1e-50 31.1842 910
6 739 733 - MS53_0057 Mycoplasma synoviae 8 745 <1e-50 33.7802 1045
13 733 720 - MHP7448_0528 Mycoplasma hyopneumoniae 7448 51 775 <1e-50 32.6087 959
1 786 785 - MHP7448_0033 Mycoplasma hyopneumoniae 7448 1 787 <1e-50 32.4561 1074
20 695 675 - MMOB4940 Mycoplasma mobile 88 766 <1e-50 33.908 946
5 714 709 - MMOB4600 Mycoplasma mobile 7 713 <1e-50 37.9642 1130
4 714 710 - MSC_0511 Mycoplasma mycoides subsp. mycoides SC 3 710 <1e-50 40.3606 1331
21 771 750 - MSC_0007 Mycoplasma mycoides subsp. mycoides SC 35 759 <1e-50 31.2094 900
3 279 276 - LIC_13347 Leptospira interrogans serovar Copenhage 8 269 1e-27 30.7692 296
3 756 753 - LIC_10006 Leptospira interrogans serovar Copenhage 27 788 <1e-50 31.4286 928
4 744 740 - MYCGA4190 Mycoplasma gallisepticum 2 739 <1e-50 42.4566 1460
32 331 299 - Bacillus subtilis subsp. subtilis 2 302 <1e-50 43.8538 733
32 331 299 - Bacillus subtilis subsp. subtilis 2 302 <1e-50 43.8538 743
140 331 191 - Bacillus subtilis subsp. subtilis 1 193 3e-35 35.2332 364
29 331 302 - Bacillus subtilis subsp. subtilis 1 304 <1e-50 42.4342 715
29 331 302 - Bacillus subtilis subsp. subtilis 1 304 <1e-50 43.0921 725
1 736 735 - MYPE6470 Mycoplasma penetrans 1 741 <1e-50 40.4826 1353
4 696 692 - MYPE40 Mycoplasma penetrans 15 709 <1e-50 31.4367 926
33 340 307 - Bacillus subtilis subsp. subtilis 1 309 <1e-50 43.0421 741
28 331 303 - Bacillus subtilis subsp. subtilis 2 306 <1e-50 43.9344 751
51 287 236 - Bacillus subtilis subsp. subtilis 1 238 <1e-50 44.958 620
2 789 787 - Mycoplasma pulmonis 10 791 <1e-50 34.128 1155
20 694 674 - Mycoplasma pulmonis 76 753 <1e-50 34.3885 963
External IDs
COG
COG0188L
EC number
5.99.1.-
Gene ID
877177
GI
13507862
GO
DNA replication, recombination and repair
Home COG
L
InterPro
IPR002205|DNA topoisomerase, type IIA, subunit A or C-terminal
InterPro
IPR013758|DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta
InterPro
IPR005741|DNA topoisomerase IV, subunit A, Gram-positive
InterPro
IPR006691|DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel
InterPro
IPR013760|DNA topoisomerase, type IIA, central
Old MP number
MP031
Pathway
Division, DNA maintenance and repair
PDB homologs
1suu_A
PDB homologs
1bgw_
PDB homologs
1ab4_
PDB homologs
1AB4
Pfam
PF03989
Pfam
PF00521
PID
g1673679
RefSeq
NP_109811.1
Swiss-Prot protein ID
PARC_MYCPN
phylomeDB tree
PARC_MYCPN
UniProt
P75352
Transcription
IMAGE BROWSERS

OPERON OP54 (Genomic Overview)
Region:152540-160900

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STRING image

STRING of Mpn123STRING legend

PDB image(s)

1suu

PDB 1suu

1bgw

PDB 1bgw

1ab4

PDB 1ab4

1AB4

PDB 1AB4