MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene prs (MPN073)
Name 
prs
Stable ID 
MPN073
Location 
86925 - 88091 -
Sequence 
    1  ATGAGATTAA ACAAATTACG GCACGCCAAA AGCAAGAAGG ACTTTCCATT ATTCCACTTA
   61  AAGTGTTCTT TAAAAATGGC AAAATTAAAA TGGAAATCTG GTTGGCCAAA CCTAAGAAAA
  121  AATTTGATAA ACGTGAAGCC ATCAAAAGTA AAACGATCCA GCGCGAATTG CGCCAACAAT
  181  ATGGATCGCC ATAACCACGT TGTTTTTAGC TTATCGAAAA CCCACGACTT AGTTAGTCGT
  241  ATTTGTCAGA AACTCAAAAT GCCCATGGGG TTAATTACCC ATAATGAGTT TGCTGATGGG
  301  GAGACCTACA TCCGCTTTGA GGAGTCTGTG CGCAATAAGG ATGTTTTTAT CTTTCAGTCT
  361  ACCTGTGCGC CAGTCAACGA TTCCTTAATG GAATTGTTAA TAGCAATTGA TGCCTTAAAA
  421  CGGGGTAGTG CAAAAAGTAT TACCGCCATT TTGCCGTACT ATGGTTATGC ACGGCAAGAT
  481  CGCAAAACAA TGGGACGCGA ACCGATAACT AGTAAATTAG TAGCGGATTT GTTAACCACG
  541  GCTGGGGTGA GCCGCGTAGC TTTAACCGAC ATCCACAGCG ACCAAACCCA GGGTTTCTTT
  601  AATATACCCG TGGATACATT GCGAACCTAC CACGTCTTTT TAACCCGCAC TGTAGAGCTG
  661  TTAGGTAAAA AAGACCTTGT GGTGGTGTCC CCCGATTATG GCGGTGTAAA GCGGGCAAGG
  721  TTAATTGCAA CATCTTTGGA ACTACCGCTA GCGATTATTG ACAAGCGTCG CCCAGCCCAC
  781  AATGTAGCGG AATCAATTAA TGTCTTGGGT GAAGTAGCGA ACAAAAACTG TCTAATAGTG
  841  GACGACATGA TTGACACCGG TGGTACGGTA ATAGCAGCAG CTAAACTACT CCGGGAACAC
  901  CATGCCAAAA AGGTCTGTGT CATGGCCACC CATGGTTTGT TTAACGGTGA AGCACCGCAA
  961  CGCTTCCAAA AGGCCTTTAA CGAAGGCTTA GTGGACTATT TGTTTGTCTC CAACTCCATT
 1021  CCTCAAACTA AGTTTGACCA GTGTCCCCAG TTTCAGGTAA TTGATCTAGC ACCGTTATTT
 1081  GAAGAGGTGT TATTGTGTTA CGCTAATAAC TCTTCCATTT CTGCCATTTA TACGCGCCAC
 1141  ATTGAATGGA TAAAAAAACA CGTCTAA
Download Sequence
Operon 
OP563
Operon location 
86485 - 88480
Protein (mpn073)
Name 
Ribose-phosphate pyrophosphokinase (RPPK) (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase)
Stable ID 
Mpn073
Molecular Weight 
42680
Isoelectric Point 
10
Localization 
SIGNALP
Comment ATP + Ribose5Phosphate = PhosphoRibosylPyrroPhosphate + AMP.
Sequence 
MRLNKLRHAKSKKDFPLFHLKCSLKMAKLKWKSGWPNLRKNLINVKPSKVKRSSANCANNMDRHNHVVFSLSKTHDLVSR
ICQKLKMPMGLITHNEFADGETYIRFEESVRNKDVFIFQSTCAPVNDSLMELLIAIDALKRGSAKSITAILPYYGYARQD
RKTMGREPITSKLVADLLTTAGVSRVALTDIHSDQTQGFFNIPVDTLRTYHVFLTRTVELLGKKDLVVVSPDYGGVKRAR
LIATSLELPLAIIDKRRPAHNVAESINVLGEVANKNCLIVDDMIDTGGTVIAAAKLLREHHAKKVCVMATHGLFNGEAPQ
RFQKAFNEGLVDYLFVSNSIPQTKFDQCPQFQVIDLAPLFEEVLLCYANNSSISAIYTRHIEWIKKHV
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation SSANcANNmDR 53 64 M
Oxidation KTmGREPITSK 162 173 M
Oxidation TmGREPITSK 163 173 M
GENE/PROTEIN prs (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
36-383 PTHR10210:SF14 (n.a.) NULL 0
36-383 PTHR10210 (n.a.) NULL 0
61-224 G3DSA:3.40.50.2020 (n.a.) NULL 0
66-378 TIGR01251 (IPR005946) Phosphoribosyl pyrophosphokinase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009165'>'nucleotide' == '' ? '': 'nucleotide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009165)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0000287'>'magnesium' == '' ? '': 'magnesium'; 'ion' == '' ? '': 'ion'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0000287) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004749'>'ribose' == '' ? '': 'ribose'; 'phosphate' == '' ? '': 'phosphate'; 'diphosphokinase' == '' ? '': 'diphosphokinase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004749)

0
131-371 SSF53271 (n.a.) NULL 0
190-205 PS00114 (IPR000842) Phosphoribosyl pyrophosphate synthetase, conserved Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009156'>'ribonucleoside' == '' ? '': 'ribonucleoside'; 'monophosphate' == '' ? '': 'monophosphate'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009156) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0044249'>'cellular' == '' ? '': 'cellular'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0044249)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0000287'>'magnesium' == '' ? '': 'magnesium'; 'ion' == '' ? '': 'ion'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0000287) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004749'>'ribose' == '' ? '': 'ribose'; 'phosphate' == '' ? '': 'phosphate'; 'diphosphokinase' == '' ? '': 'diphosphokinase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004749)

0
223-308 PF00156 (IPR000836) Phosphoribosyltransferase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009116'>'nucleoside' == '' ? '': 'nucleoside'; 'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009116)

3.3e-16
225-346 G3DSA:3.40.50.2020 (n.a.) NULL 1.4013e-43
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
68 377 309 - b1207 Escherichia coli 6 313 <1e-50 43.131 678
67 377 310 - MARTH_orf112 Mycoplasma arthritidis 10 316 <1e-50 45.8599 692
61 387 326 - MAG1870 Mycoplasma agalactiae 1 324 <1e-50 41.5152 660
77 385 308 - MCJ_000270 Mycoplasma conjunctivae 7 312 <1e-50 43.4505 589
61 385 324 - MCAP_0104 Mycoplasma capricolum subsp. capricolum 1 333 <1e-50 42.0896 703
63 385 322 - MYCGA5750 Mycoplasma gallisepticum 4 328 <1e-50 58.4615 942
49 388 339 - MG058 Mycoplasma genitalium 5 344 <1e-50 76.4706 1410
60 377 317 - MHP7448_0654 Mycoplasma hyopneumoniae 7448 2 317 <1e-50 42.7245 591
65 380 315 - MHO_3550 Mycoplasma hominis 8 319 <1e-50 42.9467 656
59 377 318 - MMOB5660 Mycoplasma mobile 5 318 <1e-50 40.3077 501
61 385 324 - MSC_0952 Mycoplasma mycoides subsp. mycoides SC 14 346 <1e-50 42.3881 702
64 380 316 - MYPE9450 Mycoplasma penetrans 6 324 <1e-50 49.5298 815
68 377 309 - Caulobacter crescentus NA1000 3 311 <1e-50 42.9936 632
68 325 257 - Lactococcus lactis subsp. lactis KF147 10 267 <1e-50 45.7692 582
61 381 320 - Lactococcus lactis subsp. lactis KF147 1 319 <1e-50 44.4444 692
68 377 309 - LIC_10429 Leptospira interrogans serovar Copenhage 7 311 <1e-50 43.0868 678
59 384 325 - MS53_0150 Mycoplasma synoviae 2 325 <1e-50 40.1216 615
62 377 315 - Rv1017c Mycobacterium tuberculosis 8 322 <1e-50 41.3793 621
58 378 320 - Bacillus subtilis subsp. subtilis 2 317 <1e-50 43.3022 680
58 378 320 - Bacillus subtilis subsp. subtilis 2 317 <1e-50 43.3022 680
61 382 321 - Mycoplasma pulmonis 1 319 <1e-50 42.4615 722
External IDs
COG 
COG0462FE
EC number 
2.7.6.1
Gene ID 
877326
GI 
13507812
GO 
Nucleotide transport and metabolism
Home COG 
F
InterPro 
IPR005946|Ribose-phosphate pyrophosphokinase
InterPro 
IPR000836|Phosphoribosyltransferase
InterPro 
IPR002375|Purine/pyrimidine phosphoribosyl transferase
InterPro 
IPR000842|Phosphoribosyl pyrophosphate synthetase
Old MP number 
MP082
Pathway 
Metabolism Nucleotides? tRNA modification?
PDB homologs 
1dkr_A
PDB homologs 
1ibs_A
PDB homologs 
1dku_A
PDB homologs 
1OPR
Pfam 
PF00869
Pfam 
PF00156
PID 
g1673736
RefSeq 
NP_109761.1
Swiss-Prot protein ID 
KPRS_MYCPN
phylomeDB tree 
KPRS_MYCPN
UniProt 
P75044
Transcription
IMAGE BROWSERS

OPERON OP563 (Genomic Overview)
Region:86485-88480

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STRING image

STRING of Mpn073STRING legend

PDB image(s)

1dkr

PDB 1dkr

1ibs

PDB 1ibs

1dku

PDB 1dku

1OPR

PDB 1OPR
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All data provided for download in the MyMpn database is free to use. Upon doing so, please cite the original data source and the MyMpn database
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