MyMpn Project

1 ATGAGCTTTT CCCAAGTTTT CCACCAATCC CCACGTGGTT GAATCGAAGT GATTTGTGGG 61 CCGATGTTTT CCGGTAAAAC CGAAGAATTA TTGCGCAAAA TTAAGCGCTG AAAGCTCGCC 121 AAGATTCCCG TTATTATCTT TAAACCAAAG ATTGATACGC GCCAACAACA CCTCGTGAAA 181 TCCCGTAACG GTCACAGTGA TGAAGCCATT GAAATTAATT CACCTTTAGA AATCTATGAC 241 TACCTCACTA AAGATCGTTT TGATGTGGTT GCCATTGATG AAGCCCAATT CTTTTCGAGT 301 GAAATTGTCG AAGTGGTTAA ATCACTCAAT GATCTCGGCA TTAACGTCAT TGTTTCTGGT 361 TTAGACACGG ACTTCCGCGC TGAACCCTTT GGTAGCATTC CCCAACTATT AGCGATTGCC 421 GACAAGATTT GTAAGTTAGA TGCCGTTTGT AATGTCTGTG GTCAGTTAGC CCAACGCACC 481 CAGCGCATAG TGTCCAAGAG CAACGAAACC GTTTTAATTG GTGATATTGA AGCTTATGAA 541 CCACGTTGTA AGTTGCACCA ACCCAGTGCA GGGTAA

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
12-147	SSF52540 (n.a.)	NULL			5.60519e-45
12-186	PTHR11441 (IPR001267)	Thymidine kinase	Molecular Function: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004797'>'thymidine' == '' ? '': 'thymidine'; 'kinase' == '' ? '': 'kinase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004797) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)		0
12-190	PIRSF035805 (IPR001267)	Thymidine kinase	Molecular Function: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004797'>'thymidine' == '' ? '': 'thymidine'; 'kinase' == '' ? '': 'kinase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004797) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)		0
13-186	PF00265 (IPR001267)	Thymidine kinase	Molecular Function: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004797'>'thymidine' == '' ? '': 'thymidine'; 'kinase' == '' ? '': 'kinase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004797) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524)		0
147-186	SSF57716 (n.a.)	NULL			0.0000000026

Name	tdk
Stable ID	MPN044
Location	52475 - 53050 -
Sequence	1 ATGAGCTTTT CCCAAGTTTT CCACCAATCC CCACGTGGTT GAATCGAAGT GATTTGTGGG 61 CCGATGTTTT CCGGTAAAAC CGAAGAATTA TTGCGCAAAA TTAAGCGCTG AAAGCTCGCC 121 AAGATTCCCG TTATTATCTT TAAACCAAAG ATTGATACGC GCCAACAACA CCTCGTGAAA 181 TCCCGTAACG GTCACAGTGA TGAAGCCATT GAAATTAATT CACCTTTAGA AATCTATGAC 241 TACCTCACTA AAGATCGTTT TGATGTGGTT GCCATTGATG AAGCCCAATT CTTTTCGAGT 301 GAAATTGTCG AAGTGGTTAA ATCACTCAAT GATCTCGGCA TTAACGTCAT TGTTTCTGGT 361 TTAGACACGG ACTTCCGCGC TGAACCCTTT GGTAGCATTC CCCAACTATT AGCGATTGCC 421 GACAAGATTT GTAAGTTAGA TGCCGTTTGT AATGTCTGTG GTCAGTTAGC CCAACGCACC 481 CAGCGCATAG TGTCCAAGAG CAACGAAACC GTTTTAATTG GTGATATTGA AGCTTATGAA 541 CCACGTTGTA AGTTGCACCA ACCCAGTGCA GGGTAA
Download Sequence
Operon	OP584
Operon location	50425 - 53050

Name	Thymidine kinase (EC 2.7.1.21)
Stable ID	Mpn044
Molecular Weight	21010
Isoelectric Point	7
Localization	Cytoplasm
Comment	ATP + thymidine = ADP + thymidine5Phosphate.
Sequence	MSFSQVFHQSPRGWIEVICGPMFSGKTEELLRKIKRWKLAKIPVIIFKPKIDTRQQHLVKSRNGHSDEAIEINSPLEIYD YLTKDRFDVVAIDEAQFFSSEIVEVVKSLNDLGINVIVSGLDTDFRAEPFGSIPQLLAIADKICKLDAVCNVCGQLAQRT QRIVSKSNETVLIGDIEAYEPRCKLHQPSAG

Modification	Modified sequence	Relative start	Relative end	Amino acid
Oxidation	GWIEVIcGPmFSGK	13	27	M

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
6	185	179	- MAG7010	Mycoplasma agalactiae	1	178	5e-34	44.1989	339
13	184	171	- MARTH_orf165	Mycoplasma arthritidis	8	179	2e-36	43.3526	360
13	184	171	- MCJ_007010	Mycoplasma conjunctivae	8	179	5e-38	41.6185	373
13	184	171	- MHO_0550	Mycoplasma hominis	8	179	8e-37	43.3526	362
20	186	166	-	Lactococcus lactis subsp. lactis KF147	9	183	6e-18	32.3864	204
13	191	178	-	Bacillus subtilis subsp. subtilis	5	188	<1e-50	49.7297	466
13	191	178	-	Bacillus subtilis subsp. subtilis	8	191	<1e-50	49.1892	462
21	190	169	- b1238	Escherichia coli	10	189	0.0000000000008	29.2818	162
9	187	178	- MG034	Mycoplasma genitalium	9	189	<1e-50	71.8232	709
5	184	179	- MCAP_0143	Mycoplasma capricolum subsp. capricolum	10	199	2e-34	39.4737	343
13	184	171	- MS53_0521	Mycoplasma synoviae	8	177	1e-30	43.1034	310
13	184	171	- MHP7448_0608	Mycoplasma hyopneumoniae 7448	8	179	3e-40	47.3988	392
6	184	178	- MMOB6150	Mycoplasma mobile	1	178	2e-36	42.7778	359
12	191	179	- MYPE10320	Mycoplasma penetrans	10	196	5e-39	44.385	384
10	187	177	- MYCGA6630	Mycoplasma gallisepticum	9	192	<1e-50	49.4565	490
5	184	179	- MSC_0149	Mycoplasma mycoides subsp. mycoides SC	10	199	4e-34	38.4211	341
6	184	178	-	Mycoplasma pulmonis	1	179	1e-36	41.6667	363

COG	COG1435F
EC number	2.7.1.21
Gene ID	877408
GI	13507783
GO	Nucleotide transport and metabolism
Home COG	F
InterPro	IPR001267\|Thymidine kinase
Old MP number	MP110
Pathway	Metabolism, nucleotide
PDB homologs	1b0u_A
PDB homologs	1l2t_A
PDB homologs	1f3o_A
Pfam	PF00265
PID	g1673767
RefSeq	NP_109732.1
Swiss-Prot protein ID	KITH_MYCPN
phylomeDB tree	KITH_MYCPN
UniProt	P75070