MyMpn Project

Gene yaaK (MPN275)

Name	yaaK
Stable ID	MPN275
Location	325680 - 325982 +
Sequence	1 ATGAGTTTTA AAAAGATTAC CGAAATGATG CGCCAAGCTG AACGACAAAG CAAGCAAAAA 61 GCGCTTGATT TCGAGCAAAA ATTGTTTGAG TACAGCTATA AGAATGCTGC CATCAAGATT 121 ATCATTTTTG GTAATCTCAC CATTAAGTCT ATCACAATCG ATCCCGCATT AATTGACCCA 181 GAAGACAAGG TCACTTTAGA GGAGATGATT ACAGAAGCTG TCAATGAGGC TGTGGGTGAT 241 GTTAAGGCCA AGTACGACCA GTTAATGGAA GAGGCTATGC CACAGATGCC TGGGCTTTTT 301 TAA
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Operon	OP109
Operon location	325618 - 326838

Protein (mpn275)

Name	Putative uncharacterized protein yaaK
Stable ID	Mpn275
Molecular Weight	11000
Isoelectric Point	5
Localization	Cytoplasm
Comment	YbaB family in E. coli. The function of this protein is unknown, but it has been expressed and crystallized. This gene nearly always occurs next to recR and/or dnaX. YbaB is co-transcribed with recR, which appears to protect DNA strands of the replilcation fork when it is blocked by DNA damage. A deletion of the YbaB operon resulted in increased sensitivity to DNA-damaging agents compared with the wild-type strain
Sequence	MSFKKITEMMRQAERQSKQKALDFEQKLFEYSYKNAAIKIIIFGNLTIKSITIDPALIDPEDKVTLEEMITEAVNEAVGD VKAKYDQLMEEAMPQMPGLF

Post translational modifications

Modification	Modified sequence	Relative start	Relative end	Amino acid
Formylation	SFKKITEMMR	2	11
Oxidation	SFKKITEmMR	2	12	M
Oxidation	SFKKITEMmR	2	12	M
Oxidation	KITEmMR	5	12	M
Oxidation	ITEmMR	6	12	M
Oxidation	ITEMmR	6	12	M
Oxidation	ITEmmR	6	12	M
Oxidation	SITIDPALIDPEDKVTLEEmITEAVNEAVGDVK	50	83	M
Oxidation	VTLEEmITEAVNEAVGDVK	64	83	M
Oxidation	AKYDQLmEEAmPQmPGLF	83	101	M
Oxidation	YDQLmEEAmPQmPGLF	85	101	M

GENE/PROTEIN yaaK (Domains Overview)

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Domains (InterProScan)

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
1-99	TIGR00103 (IPR004401)	Uncharacterised protein family UPF0133			0
1-100	PIRSF004555 (IPR004401)	Uncharacterised protein family UPF0133			4.3e-27
3-98	G3DSA:3.30.1310.10 (IPR004401)	Uncharacterised protein family UPF0133			0.0000000000000066
3-99	SSF82607 (IPR004401)	Uncharacterised protein family UPF0133			4.6e-19
8-97	PF02575 (IPR004401)	Uncharacterised protein family UPF0133			2.8e-17

Protein Homology (BLASTP results)

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
6	88	82	- MARTH_orf159	Mycoplasma arthritidis	3	86	0.00000000003	37.2093	138
8	99	91	- MCJ_003830	Mycoplasma conjunctivae	5	93	0.00000002	32.6316	114
6	88	82	- MHO_0960	Mycoplasma hominis	5	88	0.00000006	32.1429	109
9	87	78	-	Lactococcus lactis subsp. lactis KF147	7	88	0.00000003	34.1463	116
1	100	99	- MG134	Mycoplasma genitalium	1	100	1e-38	71	374
12	98	86	- MS53_0054	Mycoplasma synoviae	5	83	0.000000000009	41.3793	143
1	82	81	- MHP7448_0257	Mycoplasma hyopneumoniae 7448	1	80	0.000001	30.1205	99
10	79	69	- MMOB0740	Mycoplasma mobile	3	77	0.000002	34.6667	97
1	99	98	- MYCGA6000	Mycoplasma gallisepticum	1	100	1e-17	40.5941	194
37	94	57	- MYPE8070	Mycoplasma penetrans	36	93	0.000000002	46.5517	125
1	98	97	-	Mycoplasma pulmonis	1	95	0.0000002	31	105

External IDs

COG	COG0718S
Gene ID	876875
GI	13508014
GO	DNA replication, recombination and repair
Home COG	L
InterPro	IPR004401\|Conserved hypothetical protein 103
Old MP number	MP560
Pathway	DNA repair and maintenance?
PDB homologs	1j8b
Pfam	PF02575
PID	g1674259
RefSeq	NP_109963.1
Swiss-Prot protein ID	Y275_MYCPN
phylomeDB tree	Y275_MYCPN
UniProt	P75502

Transcription

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OPERON OP109 (Genomic Overview)

Region:325618-326838

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STRING image

STRING legend

PDB image(s)