MyMpn Project

1 ATGCAGCGTA CTTTAAATGT TGGGGTGATC CTGTGTGAAA GCTTTATTTC CAACGCCCAA 61 AACCCAGTTA ACTCCTACAT TAAGATTTAC GAAAACGTGA GGATGTTTGA GTTTGCGATT 121 AAGCTACTTC AAGAATCGCG AATTAACTTC CAAAAGATCC TTTTATACGT TTTGGAAGAG 181 CAAATTCCAC TTGTGGAAAA AGTAGTTGCC AAGTACGAAA ACTGCTGGGT CTTTCGTTCC 241 AAGCACAACG AGGTTGAGGA CATTTATGAA GCCAAGGGCT TTATTGAAGA CAAGTACAAA 301 ATTGGTTTAA AAAGTTCTAA AAACCAAGCC TCTTCGTATT ATGACAACTG TTGTTTTGTT 361 GTCTTGGAAG CATGTCGACC TTTAACTTCT AAGAAGGTTG TTAAAAACGT GTATGAAAAG 421 GCAATGATTG ACGGTGCCGC TGTAGCTGTA CTACCGTTTG AAAGGCAGCT TGTTTGTGGT 481 GATAATACTA AGGCGGTGCG CCAGTTAAAG GACAAGGGCA ACATGAACTA TTGGCGTCAA 541 AGTAGTACTT GGGAGTTGCA ATTTCCCCAG GCTTATACGC TCAATAAGTT AAACCAGTAT 601 CATAAAAACC TCTTTATGAA GGCGCGGAAC ATGCTTGATT TAATGAACAT TTCCGCTAAG 661 AATCCCCTAA GCATTGTCGA TGGTAGTGCT TACAGCTTTC GTGTAGTTAC TAGCCTGGAC 721 TTTGAAATTT TGTTAGGTAT TTTGCGCAAT GGATAG

MQRTLNVGVILCESFISNAQNPVNSYIKIYENVRMFEFAIKLLQESRINFQKILLYVLEEQIPLVEKVVAKYENCWVFRS

KHNEVEDIYEAKGFIEDKYKIGLKSSKNQASSYYDNCCFVVLEACRPLTSKKVVKNVYEKAMIDGAAVAVLPFERQLVCG

DNTKAVRQLKDKGNMNYWRQSSTWELQFPQAYTLNKLNQYHKNLFMKARNMLDLMNISAKNPLSIVDGSAYSFRVVTSLD

FEILLGILRNG

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
31-249	G3DSA:3.90.550.10 (n.a.)	NULL			6.5e-19
53-250	SSF53448 (n.a.)	NULL			0.0000043
120-245	PF01128 (IPR001228)	4-diphosphocytidyl-2C-methyl-D-erythritol synthase	Biological Process: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008299'>'isoprenoid' == '' ? '': 'isoprenoid'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008299) Molecular Function: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003824'>'catalytic' == '' ? '': 'catalytic'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003824)		0.0044

Name	ygbP
Stable ID	MPN255
Location	305565 - 306320 +
Sequence	1 ATGCAGCGTA CTTTAAATGT TGGGGTGATC CTGTGTGAAA GCTTTATTTC CAACGCCCAA 61 AACCCAGTTA ACTCCTACAT TAAGATTTAC GAAAACGTGA GGATGTTTGA GTTTGCGATT 121 AAGCTACTTC AAGAATCGCG AATTAACTTC CAAAAGATCC TTTTATACGT TTTGGAAGAG 181 CAAATTCCAC TTGTGGAAAA AGTAGTTGCC AAGTACGAAA ACTGCTGGGT CTTTCGTTCC 241 AAGCACAACG AGGTTGAGGA CATTTATGAA GCCAAGGGCT TTATTGAAGA CAAGTACAAA 301 ATTGGTTTAA AAAGTTCTAA AAACCAAGCC TCTTCGTATT ATGACAACTG TTGTTTTGTT 361 GTCTTGGAAG CATGTCGACC TTTAACTTCT AAGAAGGTTG TTAAAAACGT GTATGAAAAG 421 GCAATGATTG ACGGTGCCGC TGTAGCTGTA CTACCGTTTG AAAGGCAGCT TGTTTGTGGT 481 GATAATACTA AGGCGGTGCG CCAGTTAAAG GACAAGGGCA ACATGAACTA TTGGCGTCAA 541 AGTAGTACTT GGGAGTTGCA ATTTCCCCAG GCTTATACGC TCAATAAGTT AAACCAGTAT 601 CATAAAAACC TCTTTATGAA GGCGCGGAAC ATGCTTGATT TAATGAACAT TTCCGCTAAG 661 AATCCCCTAA GCATTGTCGA TGGTAGTGCT TACAGCTTTC GTGTAGTTAC TAGCCTGGAC 721 TTTGAAATTT TGTTAGGTAT TTTGCGCAAT GGATAG
Download Sequence
Operon	OP102
Operon location	305047 - 307970

Name	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like
Stable ID	Mpn255
Molecular Weight	27610
Isoelectric Point	9
Localization	Cytoplasm
Comment	Also IspD. Conservation of the active site, but bulky residues in the binding pocket indicate that it might have changed substrate specificity
Sequence	MQRTLNVGVILCESFISNAQNPVNSYIKIYENVRMFEFAIKLLQESRINFQKILLYVLEEQIPLVEKVVAKYENCWVFRS KHNEVEDIYEAKGFIEDKYKIGLKSSKNQASSYYDNCCFVVLEACRPLTSKKVVKNVYEKAMIDGAAVAVLPFERQLVCG DNTKAVRQLKDKGNMNYWRQSSTWELQFPQAYTLNKLNQYHKNLFMKARNMLDLMNISAKNPLSIVDGSAYSFRVVTSLD FEILLGILRNG

Modification	Modified sequence	Relative start	Relative end	Amino acid
Oxidation	mFEFAIK	35	42	M
Methylation	NQASSYYDNccFVVLEAcRPLTSk	108	132	K
Oxidation	amIDGAAVAVLPFER	141	156	M
Oxidation	AmIDGAAVAVLPFEr	141	156	M
Oxidation	AmIDGAAVAVLPFER	141	156	M
Oxidation	QLKDKGNmNYWR	168	180	M
Oxidation	DKGNmNYWR	171	180	M
Oxidation	GNmNYWR	173	180	M
Oxidation	ARNmLDLmNISAK	208	221	M
Oxidation	NMLDLmNISAK	210	221	M
Oxidation	NmLDLmNISAK	210	221	M
Oxidation	NmLDLMNISAK	210	221	M
Oxidation	NMLDLmNISAk	210	221	M
Oxidation	NmLDLmNISAKNPLSIVDGSAYSFR	210	235	M

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
1	251	250	- MG116	Mycoplasma genitalium	1	251	<1e-50	56.9721	784

Alias	lspD
COG	COG1211I
EC number	2.7.7.60
Gene ID	876842
GI	13507994
GO	Lipid metabolism
Home COG	I
Old MP number	MP578
Pathway	Metabolism
Pathway	isoprenoid biosynthesis?
PID	g1674278
RefSeq	NP_109943.1
Swiss-Prot protein ID	Y255_MYCPN
phylomeDB tree	No orthologous found
UniProt	P75519