MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene tlyC (MPN159)
Name 
tlyC
Stable ID 
MPN159
Location 
211982 - 213256 +
Sequence 
    1  ATGGAAAGTG CCCCCAGTGG TGGCCTGTTG GCCTTAATTA TTATCAGTAT TATCCTCCTG
   61  GCTTGTATTA GTGCCGTGGT TTCGGCTTAC GAAACCGCCA TTACCTCAAT TACATCATAC
  121  AAGTGGAGCA ACTATGTCAA AACGCATAAC AAGCAAAAGA AGTTAACGAC CAAGATTGTT
  181  AACCACTTCC AAAAGAACTA TTCGGCTTGT TTAATTACCA TCTTAGTGGC CAATAACATT
  241  GTCGCCATTT TGGTTTCCAA CATCCTCTTT TTGGCTTTAG ATCAATCGAT TAAGAATCCG
  301  GCCATTTCCA GTGCCTTGAA CCTCTTAATT AGTGGGGTGT TATTGTTAAT GCTGTGTGAA
  361  ATTACTCCCA AAACCTTAGC ACGGATTAAC ATCATCCGCG TCTTGGTCTA CTTTGCGGTG
  421  GTAGTGTATT TTTTCTACAT CCTTTTTTGA CCAATTACCA AGTTAGCCAG CATTATCTTT
  481  GCCAAATACG AAAAGGCACC CCCAGTTTCC CGCCGTGATG TTTACTTCTT TATTGATGAA
  541  ATTGAGCAAA ACGGGTTATT TACCAAAGAA GACGGGCAGC TAATTAAACG GACCCTAATC
  601  TTTGACCAGG TCTTAGTTGA CCAAATCATG ATTAAGTGAA ACCGGGTGGT GTACTGTTAT
  661  GAAGGTGATC CAGTCAAGAC CATTAAGGAA AAGTTCTTGC ACGGCCAGTT TTCCAGAATG
  721  CCCGTACTCG ACCAGACAAG CAATGAAGTG GTTGGTTTTA TCCACCTCAA GGACTTGTTT
  781  AGTTCACTCG AAAAGAGCAA CGAGCCGTTT GTTTTACAGG AGTTATTGTA TCCAGCTGTT
  841  TTAGTAAGTA ACACCACACC CATCAAGCAA GCTTTGCGCC AAATGCGGTT ACACCGGGCC
  901  CACTTAGCGG TCGTGCAGGA CAAACACCAC CACACGATCG GGATTGTTTC TATGGAAGAC
  961  ATCATTGAGG AATTAGTCGG GGAAATTTAC GATGAACATG ATGAGGTGGA GGCAGTGCAA
 1021  ACGTTGGACA ACAACACCTG GTTAGTGTTA CCGAACGTAA AAGCCGCCTT TTTCTTTAAC
 1081  AAGTGGATTA AACGGGATTT AGTAAAATCA AAAAACATGA CGATCCAACG TTACTTGGCA
 1141  TCGTTTGAAA ATGATGGGTT AAACACCCAG AATAAACTAG AAACGCCGTG GTTTATTGCT
 1201  GAAGCAATTG TCGACAGCGA GAACCCCGAG CAAATTCGGT ACGAAATTCG CAAAAAGAGT
 1261  GATGTTGTGG ACTAG
Download Sequence
Operon 
OP74
Operon location 
211965 - 214528
Protein (mpn159)
Name 
Hemolysisn, TlyC-like protein
Stable ID 
Mpn159
Molecular Weight 
46640
Isoelectric Point 
7
Localization 
TMHMM
Comment Has 4 TM helices and two CBS domains; CBS (cystathionine-beta-synthase) domains are small intracellular modules, mostly found in two or four copies within a protein, that occur in several different proteins in all kingdoms of life. Tandem pairs of CBS domains can act as binding domains for adenosine derivatives and may regulate the activity of attached enzymatic or other domains. In some cases, CBS domains may act as sensors of cellular energy status by being activated by AMP and inhibited by ATP (Microb Pathog, 1994, 16:269). Magnesium and cobalt efflux protein?
Sequence 
MESAPSGGLLALIIISIILLACISAVVSAYETAITSITSYKWSNYVKTHNKQKKLTTKIVNHFQKNYSACLITILVANNI
VAILVSNILFLALDQSIKNPAISSALNLLISGVLLLMLCEITPKTLARINIIRVLVYFAVVVYFFYILFWPITKLASIIF
AKYEKAPPVSRRDVYFFIDEIEQNGLFTKEDGQLIKRTLIFDQVLVDQIMIKWNRVVYCYEGDPVKTIKEKFLHGQFSRM
PVLDQTSNEVVGFIHLKDLFSSLEKSNEPFVLQELLYPAVLVSNTTPIKQALRQMRLHRAHLAVVQDKHHHTIGIVSMED
IIEELVGEIYDEHDEVEAVQTLDNNTWLVLPNVKAAFFFNKWIKRDLVKSKNMTIQRYLASFENDGLNTQNKLETPWFIA
EAIVDSENPEQIRYEIRKKSDVVD
Post translational modifications
No post translational modifications were found
GENE/PROTEIN tlyC (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
13-190 PF01595 (IPR002550) Domain of unknown function DUF21 1.4e-26
46-349 PTHR22777 (n.a.) NULL 0
199-335 G3DSA:3.10.580.10 (n.a.) NULL 4.5e-19
201-263 SSF54631 (n.a.) NULL 0.000000000021
206-264 PF00571 (IPR000644) Cystathionine beta-synthase, core 0.0000054
210-270 PS51371 (IPR000644) Cystathionine beta-synthase, core 0
215-264 SM00116 (IPR000644) Cystathionine beta-synthase, core 0.00018
263-331 SSF54631 (n.a.) NULL 0.00000000046
275-335 PS51371 (IPR000644) Cystathionine beta-synthase, core 0
278-326 PF00571 (IPR000644) Cystathionine beta-synthase, core 0.000034
278-326 SM00116 (IPR000644) Cystathionine beta-synthase, core 0.055
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
26 318 292 - MAG2390 Mycoplasma agalactiae 22 308 2e-16 26.3158 190
24 339 315 - MARTH_orf698 Mycoplasma arthritidis 24 329 3e-23 28.8344 250
194 339 145 - Caulobacter crescentus NA1000 54 204 4e-18 34.4371 211
28 349 321 - Caulobacter crescentus NA1000 20 359 0.0000001 20.2346 121
22 334 312 - Caulobacter crescentus NA1000 17 337 2e-23 25.3776 256
99 334 235 - MCJ_001730 Mycoplasma conjunctivae 47 275 0.000000000000005 26.25 179
24 339 315 - MHO_1110 Mycoplasma hominis 42 346 8e-16 27.0186 185
193 337 144 - Lactococcus lactis subsp. lactis KF147 205 350 0.0000000000002 28.0822 168
23 349 326 - Lactococcus lactis subsp. lactis KF147 14 358 0.00000000000002 23.796 178
23 345 322 - Bacillus subtilis subsp. subtilis 10 349 2e-19 22.6087 225
102 403 301 - Bacillus subtilis subsp. subtilis 28 329 1e-18 25.4601 218
29 415 386 - Bacillus subtilis subsp. subtilis 30 419 6e-20 25.4762 229
22 354 332 - Bacillus subtilis subsp. subtilis 15 371 3e-19 23.1844 223
22 334 312 - Bacillus subtilis subsp. subtilis 11 343 3e-16 22.4852 198
23 345 322 - Bacillus subtilis subsp. subtilis 15 354 2e-19 22.6087 225
22 403 381 - Bacillus subtilis subsp. subtilis 14 399 3e-21 24.1463 240
22 334 312 - Bacillus subtilis subsp. subtilis 14 346 4e-16 22.4852 197
22 354 332 - Bacillus subtilis subsp. subtilis 15 371 3e-19 23.743 224
29 415 386 - Bacillus subtilis subsp. subtilis 30 419 6e-20 25.4762 229
22 349 327 - b4218 Escherichia coli 10 355 0.00000000007 19.4842 149
157 330 173 - b0658 Escherichia coli 20 193 0.000000000008 25.7143 157
185 349 164 - b1816 Escherichia coli 279 440 0.000003 23.6364 109
25 328 303 - b4461 Escherichia coli 21 328 0.0000000003 18.9274 144
109 343 234 - Rv2366c Mycobacterium tuberculosis 94 340 9e-21 24.5968 234
186 346 160 - b2063 Escherichia coli 282 442 0.000000000005 27.1605 159
1 423 422 - MG146 Mycoplasma genitalium 1 423 <1e-50 64.539 1469
67 347 280 - MS53_0424 Mycoplasma synoviae 59 333 0.000000000000007 26.2799 178
23 334 311 - MHP7448_0643 Mycoplasma hyopneumoniae 7448 18 318 0.000000000003 26.25 156
108 349 241 - Rv1842c Mycobacterium tuberculosis 112 363 5e-17 23.8095 202
51 331 280 - Rv1841c Mycobacterium tuberculosis 40 341 0.0000000000007 23.9344 166
27 338 311 - LIC_13143 Leptospira interrogans serovar Copenhage 20 351 1e-16 22.5225 198
23 379 356 - MYCGA4890 Mycoplasma gallisepticum 38 393 <1e-50 35.9331 622
31 361 330 - Mycoplasma pulmonis 47 372 2e-25 27.2997 269
External IDs
Alias 
YugS/GldE
COG 
COG1253R
Gene ID 
877287
GI 
13507898
GO 
Defense mechanisms
Home COG 
V
InterPro 
IPR000644|CBS
InterPro 
IPR002550|Protein of unknown function DUF21
Old MP number 
MP672
Pathway 
Virulence, Toxin
Pfam 
PF00571
Pfam 
PF01595
PID 
g1674378
RefSeq 
NP_109847.1
Swiss-Prot protein ID 
Y159_MYCPN
phylomeDB tree 
Y159_MYCPN
UniProt 
P75586
Transcription
IMAGE BROWSERS

OPERON OP74 (Genomic Overview)
Region:211965-214528

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STRING image

STRING of Mpn159STRING legend

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