MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene efp (MPN029)
Name 
efp
Stable ID 
MPN029
Location 
33979 - 34551 +
Sequence 
    1  ATGGCAGACA TGATTGAAGC GAAAAGTTTA CGCAGTGGAC AAACGATTTT TGGTCCCAAT
   61  AAAGAGATTC TGTTGGTGTT AGAAAACACC TTTAATAAGA CCGCAATGCG CCAGGGAATT
  121  GTTAAAACCA AGGTCAAAAA CTTACGCACT GGGGCCATTG TTTGGATTGA GTTTACCGGA
  181  GACAAGTTAG AACAAGTCAT TATTGACAAG AAGAAAATGA CCTTCTTGTA CAAGGATGGT
  241  GCTAACTATG TTTTTATGGA CCAACAAGAC TACAGTCAAA TTGAGATCCC CGAAAAGCAG
  301  TTAGAGTGGG AAAAGAACTT TATCACTGAA GACAGTGAAG TTACTATTAT TAGCTACCAA
  361  AGTGAAATTT TGGGCGTTAA CCTACCCGAA TTAGTGCCGA TTGAAGTGGA ATTTGCCGAA
  421  GAAGCAGTGC AAGGTAATAC CGCTAACATG GCGCGTAAAC GGGCTCGGTT AGTTTCGGGT
  481  TACGAATTAG ATGTGCCCCA GTTCATTCGT ACTGGTGATA AGATTGTGAT TTCCACCATT
  541  GACGGGAGCT ATCGTGAACG GTACAACAAG TAA
Download Sequence
Operon 
OP10
Operon location 
33046 - 36000
Protein (mpn029)
Name 
Elongation factor P (EF-P)
Stable ID 
Mpn029
Molecular Weight 
20900
Isoelectric Point 
5
Localization 
Cytoplasm
Comment Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Sequence 
MADMIEAKSLRSGQTIFGPNKEILLVLENTFNKTAMRQGIVKTKVKNLRTGAIVWIEFTGDKLEQVIIDKKKMTFLYKDG
ANYVFMDQQDYSQIEIPEKQLEWEKNFITEDSEVTIISYQSEILGVNLPELVPIEVEFAEEAVQGNTANMARKRARLVSG
YELDVPQFIRTGDKIVISTIDGSYRERYNK
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation ADmIEAK 2 9 M
Oxidation ADmIEAk 2 9 M
Oxidation mTFLYk 73 79 M
Oxidation DGANYVFmDQQDYSQIEIPEK 79 100 M
Oxidation DGANYVFmDQQDYSQIEIPEKQLEWEK 79 106 M
Methylation tGDkIVISTIDGSYR 171 186 K
GENE/PROTEIN efp (Domains Overview)
Click on the features to jump to domain info

 ExportIMG
Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
2-189 PIRSF005901 (IPR020599) Translation elongation factor P/YeiP 0.00000000000014
4-66 SSF50104 (IPR008991) Translation protein SH3-like 0.00000000550001
4-66 G3DSA:2.30.30.30 (IPR014722) Translation protein SH3-like, subgroup 0.00000000071
5-188 TIGR00038 (IPR011768) Translation elongation factor P Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006414'>'translational' == '' ? '': 'translational'; 'elongation' == '' ? '': 'elongation'; ('GO' == '' ? '': 'GO';:0006414)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005737'>'cytoplasm' == '' ? '': 'cytoplasm'; ('GO' == '' ? '': 'GO';:0005737)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003746'>'translation' == '' ? '': 'translation'; 'elongation' == '' ? '': 'elongation'; 'factor' == '' ? '': 'factor'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003746)

0
7-62 PF08207 (IPR013185) Translation elongation factor, KOW-like 0.0000046
68-130 G3DSA:2.40.50.140 (IPR012340) Nucleic acid-binding, OB-fold 1.8e-24
68-132 SSF50249 (IPR016027) Nucleic acid-binding, OB-fold-like 6.6e-21
70-123 PF01132 (IPR001059) Translation elongation factor P/YeiP, central Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006414'>'translational' == '' ? '': 'translational'; 'elongation' == '' ? '': 'elongation'; ('GO' == '' ? '': 'GO';:0006414)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003746'>'translation' == '' ? '': 'translation'; 'elongation' == '' ? '': 'elongation'; 'factor' == '' ? '': 'factor'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003746)

2.2e-17
131-188 SSF50249 (IPR016027) Nucleic acid-binding, OB-fold-like 0.0000000000000067
132-187 PF09285 (IPR015365) Elongation factor P, C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0043043'>'peptide' == '' ? '': 'peptide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0043043)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005737'>'cytoplasm' == '' ? '': 'cytoplasm'; ('GO' == '' ? '': 'GO';:0005737)

0.0000000000000027
132-187 SM00841 (IPR015365) Elongation factor P, C-terminal Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0043043'>'peptide' == '' ? '': 'peptide'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0043043)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005737'>'cytoplasm' == '' ? '': 'cytoplasm'; ('GO' == '' ? '': 'GO';:0005737)

2.8e-16
132-187 G3DSA:2.40.50.140 (IPR012340) Nucleic acid-binding, OB-fold 5.6e-16
153-172 PS01275 (IPR013852) Translation elongation factor P/YeiP, conserved si 0
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
4 190 186 - MAG3080 Mycoplasma agalactiae 1 187 2e-37 43.617 369
4 187 183 - MARTH_orf281 Mycoplasma arthritidis 1 184 2e-34 41.6216 342
5 187 182 - Caulobacter crescentus NA1000 3 185 7e-18 28.8043 205
4 189 185 - MCJ_003110 Mycoplasma conjunctivae 1 186 1e-31 39.5722 318
4 187 183 - MHO_1790 Mycoplasma hominis 1 184 6e-34 41.6216 338
4 187 183 - Lactococcus lactis subsp. lactis KF147 1 184 2e-22 33.6898 242
4 187 183 - Bacillus subtilis subsp. subtilis 1 184 1e-27 36.7568 291
4 187 183 - Bacillus subtilis subsp. subtilis 1 184 1e-27 36.7568 291
31 187 156 - b4147 Escherichia coli 29 186 0.0000000000004 25.9494 164
4 187 183 - b2171 Escherichia coli 1 188 2e-16 27.5132 193
26 190 164 - LIC_20228 Leptospira interrogans serovar Copenhage 23 188 1e-21 31.9277 237
1 190 189 - MG026 Mycoplasma genitalium 1 190 <1e-50 86.8421 890
33 189 156 - Rv2534c Mycobacterium tuberculosis 29 186 1e-25 36.076 272
10 187 177 - MCAP_0519 Mycoplasma capricolum subsp. capricolum 6 183 2e-37 43.0168 369
4 184 180 - MS53_0431 Mycoplasma synoviae 1 181 6e-39 45.6044 381
4 187 183 - MHP7448_0427 Mycoplasma hyopneumoniae 7448 1 184 4e-35 41.6216 349
4 189 185 - MMOB5510 Mycoplasma mobile 1 186 1e-34 40.107 344
10 187 177 - MSC_0451 Mycoplasma mycoides subsp. mycoides SC 6 183 2e-37 43.0168 369
1 189 188 - MYCGA5110 Mycoplasma gallisepticum 1 188 <1e-50 57.672 571
1 187 186 - MYPE1580 Mycoplasma penetrans 1 186 <1e-50 54.5455 514
4 190 186 - Mycoplasma pulmonis 1 187 8e-35 40.4255 347
External IDs
COG 
COG0231J
Gene ID 
876940
GI 
13507768
GO 
Translation, ribosomal structure and biogenesis
Home COG 
J
InterPro 
IPR013852|Elongation factor P/YeiP, C-terminal
InterPro 
IPR012340|Nucleic acid-binding, OB-fold, subgroup
InterPro 
IPR011768|Elongation factor P
InterPro 
IPR001059|Elongation factor P/YeiP, central
InterPro 
IPR008994|Nucleic acid-binding, OB-fold
InterPro 
IPR013185|Elongation factor, KOW-like
Old MP number 
MP125
Pathway 
Translation
PDB homologs 
1ueb_A
PDB homologs 
1bkb_
PDB homologs 
1iz6_A
PDB homologs 
1BKB
Pfam 
PF09285
Pfam 
PF08207
Pfam 
PF01132
PID 
g1673784
RefSeq 
NP_109717.1
Swiss-Prot protein ID 
EFP_MYCPN
phylomeDB tree 
EFP_MYCPN
UniProt 
P75085
Transcription
IMAGE BROWSERS

OPERON OP10 (Genomic Overview)
Region:33046-36000

Click on the features to jump to a different MyMpn page

 ExportIMG MyGBrowser GBrowse
STRING image

STRING of Mpn029STRING legend

PDB image(s)

1ueb

PDB 1ueb

1bkb

PDB 1bkb

1iz6

PDB 1iz6

1BKB

PDB 1BKB
Site hosted by:
Copyright 2010-16, Luis Serrano group. All rights reserved.
All data provided for download in the MyMpn database is free to use. Upon doing so, please cite the original data source and the MyMpn database
CONTACT US