MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene ksgA (MPN679)
Name 
ksgA
Stable ID 
MPN679
Location 
803434 - 804225 -
Sequence 
    1  GTGAATAGTT TTTATCCTTC ACGCAAATTA GGGCAAAACT TTACGGTTGA CCAGAGTGTA
   61  ATTGCCAAAA CCTGTCGGTT AATTAAGAGT CTCAACCCAA CGGCCTTAAT TGAAGTGGGG
  121  CCGGGTAAGG GAGCGTTAAC CAAGGCTTTA CTCAAGTTAC AACTACCATA CCATGGCATA
  181  GAGTTGGATA AACGCTTAGC GGAATACCTC TTGGTCAACG AAATCTTAAC TGAAGAACAA
  241  CTAACCATTG GTGATGCCTT AAAACAAAAC TTGGATCAGT ATTTTCCTGA CACTATACCT
  301  TTGCTTTGTG GCAACATTCC CTACAGTATT AGCTCCCCTT TGATTGCTAA CTTTTTGGCT
  361  TCCAAACTAC AACAATTTGT GCTGGTGTGC CAGTGGGAGT TTGGTCAAAG GTTAGTAGCA
  421  CCGGTAAATT CGCCTAACTA TAGTGCCTTT GGTGTGTTTT GCCAATACCA TTTGCAAATT
  481  AAATCAGTTT TTAAAATTGA TAAGGTTGCT TTTAAGCCCA AGCCCCAAGT GGATTCGGTG
  541  TTAATGTTGT TAAAAAAGAA ACCCCAAGTA GCCTATGAAG CTCATTTTGG CCGGTTCTTA
  601  AAACAGTGTT TTCACCAGCG CCGCAAGCTG TTAGTCAATA ACCTCAAGCA GCTTCTCCCA
  661  CCCACCTTGT TAACTAATGT TTTACAACAA CAGGACTTGG CGGCAACGGT TAGAGCCCAA
  721  GAGTTAACCC CGACCCAGTT GTTTCGTTTG TATCTTAGCC TTAAACCACA TTTAAGCGAT
  781  GGAAAAGATT AG
Download Sequence
Operon 
OP302
Operon location 
803732 - 805863
Protein (mpn679)
Name 
Dimethyladenosine transferase (EC 2.1.1.-) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (16S rRNA dimethylase) (High level kasugamycin resistance protein ksgA) (Kasugamycin dimethyltransferase)
Stable ID 
Mpn679
Molecular Weight 
28930
Isoelectric Point 
10
Localization 
Cytoplasm
Comment 16S rRNA modification position 1518+1519. Rreaction: A->m6A->m6,6A (N6,N6-dimethyladenosine)
Sequence 
MNSFYPSRKLGQNFTVDQSVIAKTCRLIKSLNPTALIEVGPGKGALTKALLKLQLPYHGIELDKRLAEYLLVNEILTEEQ
LTIGDALKQNLDQYFPDTIPLLCGNIPYSISSPLIANFLASKLQQFVLVCQWEFGQRLVAPVNSPNYSAFGVFCQYHLQI
KSVFKIDKVAFKPKPQVDSVLMLLKKKPQVAYEAHFGRFLKQCFHQRRKLLVNNLKQLLPPTLLTNVLQQQDLAATVRAQ
ELTPTQLFRLYLSLKPHLSDGKD
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation mNSFYPSR 1 9 M
Oxidation mNSFYPSRK 1 10 M
Oxidation IDKVAFKPKPQVDSVLmLLK 166 186 M
Oxidation VAFKPKPQVDSVLmLLK 169 186 M
GENE/PROTEIN ksgA (Domains Overview)
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 ExportIMG
Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-255 PTHR11727 (IPR001737) Ribosomal RNA adenine methylase transferase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0000154'>'rRNA' == '' ? '': 'rRNA'; 'modification' == '' ? '': 'modification'; ('GO' == '' ? '': 'GO';:0000154)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:'adenine' == '' ? '': 'adenine';'>'rRNA' == '' ? '': 'rRNA'; ('adenine' == '' ? '': 'adenine';-'N' == '' ? '': 'N';6 <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008649'>'rRNA' == '' ? '': 'rRNA'; 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008649)

2.8e-39
4-254 TIGR00755 (IPR011530) Ribosomal RNA adenine dimethylase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006364'>'rRNA' == '' ? '': 'rRNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0006364)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0016433'>'rRNA' == '' ? '': 'rRNA'; ('adenine' == '' ? '': 'adenine';) 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0016433)

0
4-261 SSF53335 (n.a.) NULL 0
8-254 PF00398 (IPR001737) Ribosomal RNA adenine methylase transferase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0000154'>'rRNA' == '' ? '': 'rRNA'; 'modification' == '' ? '': 'modification'; ('GO' == '' ? '': 'GO';:0000154)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:'adenine' == '' ? '': 'adenine';'>'rRNA' == '' ? '': 'rRNA'; ('adenine' == '' ? '': 'adenine';-'N' == '' ? '': 'N';6 <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008649'>'rRNA' == '' ? '': 'rRNA'; 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008649)

1.4e-38
12-188 G3DSA:3.40.50.150 (n.a.) NULL 1.2e-40
23-188 SM00650 (IPR020598) Ribosomal RNA adenine methylase transferase, N-ter Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0000154'>'rRNA' == '' ? '': 'rRNA'; 'modification' == '' ? '': 'modification'; ('GO' == '' ? '': 'GO';:0000154)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:'adenine' == '' ? '': 'adenine';'>'rRNA' == '' ? '': 'rRNA'; ('adenine' == '' ? '': 'adenine';-'N' == '' ? '': 'N';6 <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008649'>'rRNA' == '' ? '': 'rRNA'; 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008649)

7.20003e-35
36-63 PS01131 (IPR020596) Ribosomal RNA adenine methylase transferase, conse Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0000154'>'rRNA' == '' ? '': 'rRNA'; 'modification' == '' ? '': 'modification'; ('GO' == '' ? '': 'GO';:0000154)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:'adenine' == '' ? '': 'adenine';'>'rRNA' == '' ? '': 'rRNA'; ('adenine' == '' ? '': 'adenine';-'N' == '' ? '': 'N';6 <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008649'>'rRNA' == '' ? '': 'rRNA'; 'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008649)

0
189-254 G3DSA:1.10.8.100 (IPR023165) rRNA adenine dimethylase-like 0.00000000000019
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
8 246 238 - b0051 Escherichia coli 13 256 3e-16 28.1124 193
8 251 243 - MARTH_orf007 Mycoplasma arthritidis 7 249 2e-16 25.9109 188
8 255 247 - MAG0510 Mycoplasma agalactiae 20 268 3e-21 29.5276 230
1 243 242 - MCJ_000290 Mycoplasma conjunctivae 1 244 6e-21 27.5304 228
11 209 198 - MCAP_0004 Mycoplasma capricolum subsp. capricolum 8 215 0.000000003 26.5403 128
2 254 252 - MYCGA0100 Mycoplasma gallisepticum 13 265 1.4013e-45 38.2812 441
1 263 262 - MG463 Mycoplasma genitalium 1 259 <1e-50 55.1331 761
6 250 244 - MHP7448_0652 Mycoplasma hyopneumoniae 7448 6 250 0.000000000000003 26.6932 179
8 251 243 - MHO_0080 Mycoplasma hominis 6 250 7e-16 26.2745 184
8 242 234 - MMOB5640 Mycoplasma mobile 7 241 3e-19 28.6307 213
11 209 198 - MSC_0004 Mycoplasma mycoides subsp. mycoides SC 8 215 0.000000008 26.0664 124
2 254 252 - MYPE10390 Mycoplasma penetrans 16 265 1e-26 29.1829 279
8 256 248 - Lactococcus lactis subsp. lactis KF147 28 291 3e-18 25.9259 208
6 263 257 - LIC_10354 Leptospira interrogans serovar Copenhage 25 282 0.00000005 26.087 122
6 254 248 - MS53_0364 Mycoplasma synoviae 8 258 9e-21 31.3725 226
8 218 210 - Caulobacter crescentus NA1000 27 243 0.00000000000005 28.6364 174
3 243 240 - Bacillus subtilis subsp. subtilis 19 276 2e-16 25.8687 196
3 243 240 - Bacillus subtilis subsp. subtilis 19 276 6e-16 25.4826 192
6 255 249 - Mycoplasma pulmonis 3 252 3e-17 26.1719 196
External IDs
COG 
COG0030J
EC number 
2.1.1.-
Gene ID 
876770
GI 
13508418
GO 
Translation, ribosomal structure and biogenesis
Home COG 
J
InterPro 
IPR011530|RRNA 16S rRNA dimethylase
InterPro 
IPR001737|Ribosomal RNA adenine methylase transferase
Old MP number 
MP163
Pathway 
rRNA metabolism
PDB homologs 
1yub_
PDB homologs 
1qam_A
PDB homologs 
1qyr
Pfam 
PF08242
Pfam 
PF08241
Pfam 
PF00398
PID 
g1673824
RefSeq 
NP_110368.1
Swiss-Prot protein ID 
KSGA_MYCPN
phylomeDB tree 
KSGA_MYCPN
UniProt 
P75113
Transcription
IMAGE BROWSERS

OPERON OP302 (Genomic Overview)
Region:803732-805863

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STRING image

STRING of Mpn679STRING legend

PDB image(s)

1yub

PDB 1yub

1qam

PDB 1qam

1qyr

PDB 1qyr
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