MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene hpt (MPN672)
Name 
hpt
Stable ID 
MPN672
Location 
796612 - 797139 -
Sequence 
    1  ATGGGCATTA AATCTATCAT CATTGATCAA AAACAGGTTG AAGCGGGTTG TAACGCTGCG
   61  CTCAAATGGT GTAATGAACA TTTTGCTGGT AAACAGGTCA TAGTATTAGG GATCTTGAAG
  121  GGTTGTATTC CCTTTTTGGG CAAACTTATT AGTCAGTTTA CCTTTGATTT ACAACTGGAC
  181  TTTGTGGCAG TCGCTTCTTA CCATGGTGGC AGTCGCCAAC AAGAAGCACC GAAGATTGTC
  241  CTAGATATGT CCCATGACCC TAAAGGCAAG GACATTCTTT TAATAGAAGA CATAGTCGAC
  301  AGTGGTCGTT CTATTAAATT AGTATTGGAC TTACTCCACA CCCGAAAGGC CAAAAGTGTG
  361  ATCTTAGTGA GCTTCATTGA AAAGCTCAAA CCCAGGGAAG CTGACATTAA GGTGGACTAT
  421  TCTTGCTTTA AAAACCAAGA CGAATTCTTG GTTGGTTTTG GGTTAGACTA CCAGGGCTTT
  481  TATCGCAATT TACCCTATGT TGGTGTCTTT GATCCTGAAG ATAATTAA
Download Sequence
Operon 
OP308
Operon location 
794180 - 797662
Protein (mpn672)
Name 
Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) (HGPRT) (EC 2.4.2.8)
Stable ID 
Mpn672
Molecular Weight 
19250
Isoelectric Point 
7
Localization 
Cytoplasm
Comment nosine monophosphate + pyrrophosphate = hypoxanthine + phosphoribosylpyrrophospate; note: Guanine and 6-mercaptopurine can replace hypoxanthine
Sequence 
MGIKSIIIDQKQVEAGCNAALKWCNEHFAGKQVIVLGILKGCIPFLGKLISQFTFDLQLDFVAVASYHGGSRQQEAPKIV
LDMSHDPKGKDILLIEDIVDSGRSIKLVLDLLHTRKAKSVILVSFIEKLKPREADIKVDYSCFKNQDEFLVGFGLDYQGF
YRNLPYVGVFDPEDN
Post translational modifications
No post translational modifications were found
GENE/PROTEIN hpt (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
3-173 SSF53271 (n.a.) NULL 1.80067e-42
3-173 G3DSA:3.40.50.2020 (n.a.) NULL 0
5-123 PF00156 (IPR000836) Phosphoribosyltransferase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009116'>'nucleoside' == '' ? '': 'nucleoside'; 'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009116)

1e-17
6-171 TIGR01203 (IPR005904) Hypoxanthine phosphoribosyl transferase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006166'>'purine' == '' ? '': 'purine'; 'ribonucleoside' == '' ? '': 'ribonucleoside'; 'salvage' == '' ? '': 'salvage'; ('GO' == '' ? '': 'GO';:0006166)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005737'>'cytoplasm' == '' ? '': 'cytoplasm'; ('GO' == '' ? '': 'GO';:0005737)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004422'>'hypoxanthine' == '' ? '': 'hypoxanthine'; 'phosphoribosyltransferase' == '' ? '': 'phosphoribosyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004422)

0
25-175 PTHR22573:SF9 (n.a.) NULL 1.79997e-41
25-175 PTHR22573 (n.a.) NULL 1.79997e-41
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
3 173 170 - MAG3840 Mycoplasma agalactiae 9 180 2e-38 40.6977 376
3 170 167 - MARTH_orf377 Mycoplasma arthritidis 6 174 2e-32 35.503 324
33 171 138 - Caulobacter crescentus NA1000 52 193 0.0000000000001 26.7606 168
3 175 172 - MHO_1940 Mycoplasma hominis 8 183 1e-31 38.6364 317
3 173 170 - Lactococcus lactis subsp. lactis KF147 5 175 3e-28 35.0877 292
24 173 149 - Lactococcus lactis subsp. lactis KF147 31 179 1e-36 47.3333 365
3 172 169 - Bacillus subtilis subsp. subtilis 6 175 4e-25 36.4706 269
3 172 169 - Bacillus subtilis subsp. subtilis 5 174 4e-25 36.4706 269
3 173 170 - Rv3624c Mycobacterium tuberculosis 23 199 7e-20 28.2486 222
6 168 162 - b0125 Escherichia coli 7 171 2e-26 31.5152 278
1 174 173 - MG458 Mycoplasma genitalium 1 174 <1e-50 72.9885 692
2 175 173 - MCAP_0765 Mycoplasma capricolum subsp. capricolum 6 183 1e-26 31.2849 275
3 171 168 - MCAP_0216 Mycoplasma capricolum subsp. capricolum 8 181 3e-32 36.2069 324
3 171 168 - MS53_0381 Mycoplasma synoviae 7 176 3e-36 40 357
3 173 170 - MHP7448_0262 Mycoplasma hyopneumoniae 7448 6 177 4e-31 37.7907 313
6 173 167 - MMOB4340 Mycoplasma mobile 13 181 9e-27 32.5444 276
2 175 173 - MSC_0848 Mycoplasma mycoides subsp. mycoides SC 6 183 2e-26 31.2849 274
3 171 168 - MSC_0256 Mycoplasma mycoides subsp. mycoides SC 8 181 3e-32 36.2069 324
24 172 148 - LIC_13438 Leptospira interrogans serovar Copenhage 29 176 2e-17 29.5302 200
3 168 165 - MYCGA0250 Mycoplasma gallisepticum 8 173 9.80909e-45 47.5904 430
3 170 167 - MYPE10260 Mycoplasma penetrans 5 173 7e-34 35.503 339
26 173 147 - MYPE5810 Mycoplasma penetrans 32 181 0.000000003 25.1656 126
3 173 170 - Mycoplasma pulmonis 16 188 2e-35 40.4624 352
External IDs
COG 
COG0634F
EC number 
2.4.2.8
Gene ID 
877019
GI 
13508411
GO 
Nucleotide transport and metabolism
Home COG 
F
InterPro 
IPR005904|Hypoxanthine phosphoribosyl transferase
InterPro 
IPR002375|Purine/pyrimidine phosphoribosyl transferase
InterPro 
IPR000836|Phosphoribosyltransferase
Old MP number 
MP170
Pathway 
Metabolism nucleotide
PDB homologs 
1g9s_A
PDB homologs 
1HGX-B
PDB homologs 
1j7j_A
PDB homologs 
1r3u
Pfam 
PF00156
PID 
g1673832
RefSeq 
NP_110361.1
Swiss-Prot protein ID 
HPRT_MYCPN
phylomeDB tree 
HPRT_MYCPN
UniProt 
P75119
Transcription
IMAGE BROWSERS

OPERON OP308 (Genomic Overview)
Region:794180-797662

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STRING image

STRING of Mpn672STRING legend

PDB image(s)

1g9s

PDB 1g9s

1HGX

PDB 1HGX

1j7j

PDB 1j7j

1r3u

PDB 1r3u
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