Gene trmD (MPN659)
Name
trmD
Stable ID
MPN659
Location
783443 - 784075 -
Sequence
    1  ATGGCCCAAG CTCAAAAAGC AAAGCTCGTT GAGTTTGAAG TAATTAACTG AAGGCAGTAT
   61  TGCAAGGACA AACACCAAAC GGTTGATGAT ATGGCTTACG GAGGAGGTGG CGGGATGGTT
  121  CTAAAAGCTG AACCAATTCT CAAAGCTTTA AAGGCTTGTA GAACTCCACA ATCGAAAGTA
  181  GTTTTATTAT CACCTGAGGG ACAACAGTTT TCCCAACCCA TGGCGCAAGC TTTAACCCAA
  241  ACGGAACACC TCATTTTGAT CTGTGGTCAC TATGAGGGCT TTGATTACCG CTTGTATAAA
  301  CATGTCGATC AAATTATTTC GTTAGGTGAC TTTGTGTTGA GTGGTGGGGA GTTAGTGGCT
  361  TTAAGTGTGA TTGATGCCAC TGTTCGTTTA ATTAAGGGTG TCATTAATGA TCAGAGCTTA
  421  ATCCACGAAT CATTTAACAA CTACTTACTG GATTTCCCCG CTTACACTAG GCCATATGAT
  481  CTAGACGGGG ATAAGGTACC TGAAATATTA TTATCAGGTG ACCATAAAAA GATAGAGGCT
  541  TATCGCAAAG AACAACAACT GCTCAGAACG GCTCAATACC GTCCTGATTT GTATAAGCAA
  601  TATTTAGCAA AGAAAGATGA AAAAAATAAA TAA
Download Sequence
Operon
OP315
Operon location
781243 - 784455
Protein (mpn659)
Name
tRNA (guanine-N(1)-)-methyltransferase (EC 2.1.1.31) (M1G-methyltransferase) (tRNA [GM37] methyltransferase)
Stable ID
Mpn659
Molecular Weight
23100
Isoelectric Point
8
Localization
Cytoplasm
Comment tRNA modification
Sequence
MAQAQKAKLVEFEVINWRQYCKDKHQTVDDMAYGGGGGMVLKAEPILKALKACRTPQSKVVLLSPEGQQFSQPMAQALTQ
TEHLILICGHYEGFDYRLYKHVDQIISLGDFVLSGGELVALSVIDATVRLIKGVINDQSLIHESFNNYLLDFPAYTRPYD
LDGDKVPEILLSGDHKKIEAYRKEQQLLRTAQYRPDLYKQYLAKKDEKNK
Post translational modifications
No post translational modifications were found
GENE/PROTEIN trmD (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-195 PF01746 (IPR016009) tRNA (guanine-N1-)-methyltransferase 0
1-208 SSF75217 (n.a.) NULL 0
1-210 PIRSF000386 (IPR002649) tRNA (guanine-N1-)-methyltransferase, bacteria Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008033'>'tRNA' == '' ? '': 'tRNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0008033)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003723'>'RNA' == '' ? '': 'RNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003723) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009019'>'tRNA' == '' ? '': 'tRNA'; ('guanine' == '' ? '': 'guanine';-'N' == '' ? '': 'N';1-)-'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0009019)

0
1-210 TIGR00088 (IPR002649) tRNA (guanine-N1-)-methyltransferase, bacteria Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008033'>'tRNA' == '' ? '': 'tRNA'; 'processing' == '' ? '': 'processing'; ('GO' == '' ? '': 'GO';:0008033)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003723'>'RNA' == '' ? '': 'RNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003723) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009019'>'tRNA' == '' ? '': 'tRNA'; ('guanine' == '' ? '': 'guanine';-'N' == '' ? '': 'N';1-)-'methyltransferase' == '' ? '': 'methyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0009019)

0
2-135 G3DSA:3.40.1280.10 (n.a.) NULL 0
144-208 G3DSA:1.10.1270.20 (IPR023148) tRNA (guanine-N1-)-methyltransferase, C-terminal 4.5e-23
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
2 210 208 - b2607 Escherichia coli 23 235 3e-38 41.1215 382
1 208 207 - MARTH_orf246 Mycoplasma arthritidis 22 224 <1e-50 46.89 472
1 200 199 - MAG6260 Mycoplasma agalactiae 22 222 <1e-50 41.791 444
1 197 196 - MCAP_0545 Mycoplasma capricolum subsp. capricolum 22 219 <1e-50 42.9293 495
1 201 200 - MYCGA6250 Mycoplasma gallisepticum 22 229 <1e-50 52.4038 565
1 210 209 - MG445 Mycoplasma genitalium 22 231 <1e-50 76.6667 883
1 208 207 - MHP7448_0285 Mycoplasma hyopneumoniae 7448 22 227 <1e-50 43.0622 464
1 200 199 - MHO_2600 Mycoplasma hominis 22 220 <1e-50 48.2587 471
9 197 188 - MMOB4290 Mycoplasma mobile 1 186 <1e-50 45.5026 461
1 197 196 - MSC_0427 Mycoplasma mycoides subsp. mycoides SC 22 219 <1e-50 42.9293 490
1 202 201 - MYPE1020 Mycoplasma penetrans 22 223 <1e-50 50.495 580
1 207 206 - Lactococcus lactis subsp. lactis KF147 21 231 <1e-50 45.0237 471
3 186 183 - LIC_11558 Leptospira interrogans serovar Copenhage 24 211 8e-36 39.8936 360
1 200 199 - MS53_0011 Mycoplasma synoviae 22 222 <1e-50 42.7861 448
2 197 195 - Rv2906c Mycobacterium tuberculosis 22 226 7e-39 39.5122 387
9 209 200 - Caulobacter crescentus NA1000 33 235 2e-37 38.4236 373
1 201 200 - Bacillus subtilis subsp. subtilis 22 227 <1e-50 48.5577 515
1 201 200 - Bacillus subtilis subsp. subtilis 22 227 <1e-50 48.5577 515
1 205 204 - Mycoplasma pulmonis 23 225 <1e-50 41.7476 465
External IDs
EC number
2.1.1.31
Gene ID
877016
GI
13508398
GO
Translation, ribosomal structure and biogenesis
Home COG
J
InterPro
IPR003439|ABC Transporter related
InterPro
IPR002649|tRNA (guanine-N1-)-methyltransferase
Old MP number
MP183
Pathway
Translation? tRNA metabolism
PDB homologs
1ual_A
PDB homologs
1uak_A
PDB homologs
1uaj_A
Pfam
PF01746
PID
g1673846
RefSeq
NP_110348.1
Swiss-Prot protein ID
TRMD_MYCPN
phylomeDB tree
TRMD_MYCPN
UniProt
P75132
Transcription
IMAGE BROWSERS

OPERON OP315 (Genomic Overview)
Region:781243-784455

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STRING image

STRING of Mpn659STRING legend

PDB image(s)

1ual

PDB 1ual

1uak

PDB 1uak

1uaj

PDB 1uaj