Gene tim (MPN629)
Name
tim
Stable ID
MPN629
Location
755782 - 756516 -
Sequence
    1  ATGCGTACGA AATACCTAAT TGGTAACTGA AAGACAAATA AGGATTTACA CCAAGCGTTG
   61  GCCTTTGTGG AGCAATTTAA ACAGCACCCT GCTAAAACTA AGGCGGTTTT GGGTATTGCC
  121  CCAGTCCACG TCCACTTAAC CGAGGTAAAC AAAGTCTTGC CTAATAACCT CTTACTGTTA
  181  GCCCAAGACG CTAACTTTAT TGCTAGTGGT TCTTACACTG GTACGGTGAG CTATACCCAA
  241  CTGCAAGACA TTAAGGTCAA CAGTGTCATT ATTGGTCACT CGGAACGGCG AAAGTACTTT
  301  AACGAAACAG CGCAAGTTAT TAATCAAAAA CTAAAAGCCT GTTTACAAGC TGGAATGTTA
  361  GTCGTGCTCT GTATTGGTGA AACGGAAGGT CAACCAATTA GTTTTCTCAA AGAAGACTTA
  421  ACCCAAGTCT TGCAAGGCAT TGACCTAAGC TTACTCAAAC AGTTAGTGAT TGCTTACGAA
  481  CCAATTTGAG CAATTGGTAC GGGTAAAACC GCTACACCGG AAATTGCTAA TAACACAATT
  541  GCCCAAATTC GCGTGTACCT TAGTGAACTG TACAACAAGG AAATTGCCCA ACAAACCTCG
  601  ATTCTCTATG GTGGTTCGGT TGCTAAGGAC AACATTAAGG AGTTAGCACA AACCGAGCAA
  661  ATTGATGGCT TTTTAGTGGG CAAGGCATCT TTGGATGTCA ACGACTTTTT AGTAATGGCA
  721  CAAGTATATG CATAA
Download Sequence
Operon
OP326
Operon location
752420 - 756522
Protein (mpn629)
Name
Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase)
Stable ID
Mpn629
Molecular Weight
26840
Isoelectric Point
8
Localization
Cytoplasm
Comment -
Sequence
MRTKYLIGNWKTNKDLHQALAFVEQFKQHPAKTKAVLGIAPVHVHLTEVNKVLPNNLLLLAQDANFIASGSYTGTVSYTQ
LQDIKVNSVIIGHSERRKYFNETAQVINQKLKACLQAGMLVVLCIGETEGQPISFLKEDLTQVLQGIDLSLLKQLVIAYE
PIWAIGTGKTATPEIANNTIAQIRVYLSELYNKEIAQQTSILYGGSVAKDNIKELAQTEQIDGFLVGKASLDVNDFLVMA
QVYA
Post translational modifications
No post translational modifications were found
GENE/PROTEIN tim (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-240 G3DSA:3.20.20.70 (IPR013785) Aldolase-type TIM barrel Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008152'>'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008152)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003824'>'catalytic' == '' ? '': 'catalytic'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003824)

0
1-243 SSF51351 (IPR000652) Triosephosphate isomerase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008152'>'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008152)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004807'>'triose' == '' ? '': 'triose';-'phosphate' == '' ? '': 'phosphate'; 'isomerase' == '' ? '': 'isomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004807)

0
1-244 PTHR21139 (IPR000652) Triosephosphate isomerase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008152'>'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008152)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004807'>'triose' == '' ? '': 'triose';-'phosphate' == '' ? '': 'phosphate'; 'isomerase' == '' ? '': 'isomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004807)

0
3-242 PS51440 (IPR000652) Triosephosphate isomerase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008152'>'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008152)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004807'>'triose' == '' ? '': 'triose';-'phosphate' == '' ? '': 'phosphate'; 'isomerase' == '' ? '': 'isomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004807)

0
4-238 PF00121 (IPR000652) Triosephosphate isomerase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008152'>'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008152)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004807'>'triose' == '' ? '': 'triose';-'phosphate' == '' ? '': 'phosphate'; 'isomerase' == '' ? '': 'isomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004807)

0
5-234 TIGR00419 (IPR000652) Triosephosphate isomerase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008152'>'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008152)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0004807'>'triose' == '' ? '': 'triose';-'phosphate' == '' ? '': 'phosphate'; 'isomerase' == '' ? '': 'isomerase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0004807)

1.2e-24
158-168 PS00171 (IPR020861) Triosephosphate isomerase, active site 0
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
1 242 241 - MAG5140 Mycoplasma agalactiae 1 250 1e-32 31.4176 329
4 241 237 - MARTH_orf397 Mycoplasma arthritidis 2 238 9e-33 33.7398 329
6 241 235 - Caulobacter crescentus NA1000 12 251 6e-26 34.8178 276
4 237 233 - MCJ_000850 Mycoplasma conjunctivae 3 235 1e-38 37.2951 381
4 242 238 - MHO_2400 Mycoplasma hominis 2 238 2e-31 33.3333 318
2 243 241 - Lactococcus lactis subsp. lactis KF147 3 251 <1e-50 40.3922 448
1 237 236 - Bacillus subtilis subsp. subtilis 4 247 5.04467e-44 38.9344 434
1 237 236 - Bacillus subtilis subsp. subtilis 1 244 6.02558e-44 38.9344 433
1 239 238 - b3919 Escherichia coli 1 245 8e-36 36.1789 362
1 244 243 - MG431 Mycoplasma genitalium 1 244 <1e-50 67.6229 872
2 244 242 - Rv1438 Mycobacterium tuberculosis 3 256 4e-32 34.252 330
1 237 236 - MCAP_0750 Mycoplasma capricolum subsp. capricolum 1 241 9.99995e-41 39.2562 398
1 236 235 - MS53_0486 Mycoplasma synoviae 1 235 5e-39 38.0567 383
4 236 232 - MHP7448_0102 Mycoplasma hyopneumoniae 7448 3 235 1e-35 36.0996 355
1 237 236 - MMOB4190 Mycoplasma mobile 1 238 4.00001e-40 38.7097 393
1 237 236 - MSC_0823 Mycoplasma mycoides subsp. mycoides SC 1 241 2.00386e-43 40.0826 421
1 236 235 - LIC_12094 Leptospira interrogans serovar Copenhage 1 246 4e-36 36.5854 364
4 237 233 - MYCGA5810 Mycoplasma gallisepticum 6 246 <1e-50 48.5477 549
4 242 238 - MYPE3730 Mycoplasma penetrans 3 247 3e-39 34.5528 387
1 226 225 - MYPE210 Mycoplasma penetrans 1 230 4e-24 29.6137 256
1 237 236 - Mycoplasma pulmonis 1 239 7.00649e-43 38.4 417
External IDs
COG
COG0149G
EC number
5.3.1.1
Gene ID
877328
GI
13508368
GO
Carbohydrate transport and metabolism  
Home COG
G
InterPro
IPR000652|Triosephosphate isomerase
Old MP number
MP213
Pathway
Metabolism energy
Pathway
Glycolysis
PDB homologs
1r2t_A
PDB homologs
1AW`-A
PDB homologs
1r2r_A
PDB homologs
1r2s_A
Pfam
PF00121
PID
g1673878
RefSeq
NP_110318.1
Swiss-Prot protein ID
TPIS_MYCPN
phylomeDB tree
TPIS_MYCPN
UniProt
P78010
Transcription
IMAGE BROWSERS

OPERON OP326 (Genomic Overview)
Region:752420-756522

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STRING image

STRING of Mpn629STRING legend

PDB image(s)

1r2t

PDB 1r2t

1AW`

PDB 1AW`

1r2r

PDB 1r2r

1r2s

PDB 1r2s