MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene ruvA (MPN535)
Name 
ruvA
Stable ID 
MPN535
Location 
656922 - 657542 +
Sequence 
    1  ATGATTGCTT CAATTTTTGG AAAAATTACC TTTGTTGGTA AGCGAAAAAT TATTGTTGAA
   61  GCCAATTGTA TTTCCTATTG GTTTAATGTG AAAGAAAACC ATAGCTTCGA AAAGAACTTG
  121  GAAAAACCGC GCCAGGTCTT CTGTCAGATC ATTAAAAGAA TGGTTACGAA CCAGATCTTG
  181  GAAGAGGGCT TTGCCTTCAA TACCTTAGAG GAAAAGGAAT GGTTTTCGAA GTTCATCGAA
  241  CTCAATGGCA TTGGTAGTAA AACTGCTTTA AACTTGCTCA ATAACAACCT CGAGGAAATG
  301  CGTGATTATA TTAAAAACAG TAACTACCAT GCCTTGACTA AGTTAACTGG TTCTAACAGT
  361  AAGGTAGCTC GCGCATTGCT GGCACTGGAA CTGTATGACC GAGACGATGG TGGTAAACGG
  421  ATTAAACCCA ACACTGCCAT GGCCAATGAC TATGATGAGA TGTTTGACAC CTTAAAGTCG
  481  TTGGGCTATA AACCCCAAGA TATCCAAAAC GCTTTGAGCA AAATTGAAAT TAAACCTAAC
  541  TTTGATGTAA GTGAAGTGAT TGCTGAAGTG ATTAAGTTAA TGTCTTTCCA GAACAATGAA
  601  GTTACAAATA AAACCGCCTA A
Download Sequence
Operon 
OP227
Operon location 
656095 - 658400
Protein (mpn535)
Name 
Holliday junction ATP-dependent DNA helicase ruvA (EC 3.6.1.-)
Stable ID 
Mpn535
Molecular Weight 
22660
Isoelectric Point 
8
Localization 
Cytoplasm
Comment The RuvAB proteins catalyze branch migration of Holliday junctions during DNA recombination in Escherichia coli. RuvA stimulates, in the presence of DNA, the weak ATPase activity of ruvB .
Sequence 
MIASIFGKITFVGKRKIIVEANCISYWFNVKENHSFEKNLEKPRQVFCQIIKRMVTNQILEEGFAFNTLEEKEWFSKFIE
LNGIGSKTALNLLNNNLEEMRDYIKNSNYHALTKLTGSNSKVARALLALELYDRDDGGKRIKPNTAMANDYDEMFDTLKS
LGYKPQDIQNALSKIEIKPNFDVSEVIAEVIKLMSFQNNEVTNKTA
Post translational modifications
No post translational modifications were found
GENE/PROTEIN ruvA (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-57 PF01330 (IPR013849) DNA helicase, Holliday junction RuvA type, domain Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006281'>'DNA' == '' ? '': 'DNA'; 'repair' == '' ? '': 'repair'; ('GO' == '' ? '': 'GO';:0006281) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006310'>'DNA' == '' ? '': 'DNA'; 'recombination' == '' ? '': 'recombination'; ('GO' == '' ? '': 'GO';:0006310)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009378'>'four' == '' ? '': 'four';-'way' == '' ? '': 'way'; 'junction' == '' ? '': 'junction'; 'helicase' == '' ? '': 'helicase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0009378)

5e-19
1-195 TIGR00084 (IPR000085) Bacterial DNA recombination protein RuvA Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006281'>'DNA' == '' ? '': 'DNA'; 'repair' == '' ? '': 'repair'; ('GO' == '' ? '': 'GO';:0006281) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006310'>'DNA' == '' ? '': 'DNA'; 'recombination' == '' ? '': 'recombination'; ('GO' == '' ? '': 'GO';:0006310)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003678'>'DNA' == '' ? '': 'DNA'; 'helicase' == '' ? '': 'helicase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003678)

0
67-127 SSF47781 (IPR010994) RuvA domain 2-like 0.00000000014
70-134 G3DSA:1.10.150.20 (n.a.) NULL 0.000000000021
76-95 SM00278 (IPR003583) Helix-hairpin-helix DNA-binding motif, class 1 Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006281'>'DNA' == '' ? '': 'DNA'; 'repair' == '' ? '': 'repair'; ('GO' == '' ? '': 'GO';:0006281)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003677'>'DNA' == '' ? '': 'DNA'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0003677)

3.1
151-194 G3DSA:1.10.8.10 (n.a.) NULL 0.000028
151-195 PF07499 (IPR011114) DNA helicase, Holliday junction RuvA type, domain Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006281'>'DNA' == '' ? '': 'DNA'; 'repair' == '' ? '': 'repair'; ('GO' == '' ? '': 'GO';:0006281) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0006310'>'DNA' == '' ? '': 'DNA'; 'recombination' == '' ? '': 'recombination'; ('GO' == '' ? '': 'GO';:0006310)

Cellular Component:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009379'>'Holliday' == '' ? '': 'Holliday'; 'junction' == '' ? '': 'junction'; 'helicase' == '' ? '': 'helicase'; 'complex' == '' ? '': 'complex'; ('GO' == '' ? '': 'GO';:0009379)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009378'>'four' == '' ? '': 'four';-'way' == '' ? '': 'way'; 'junction' == '' ? '': 'junction'; 'helicase' == '' ? '': 'helicase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0009378)

0.000000063
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
1 200 199 - MAG2230 Mycoplasma agalactiae 1 194 0.0000000000003 30.7317 160
1 202 201 - MARTH_orf388 Mycoplasma arthritidis 1 201 0.0000000000002 27.9621 162
5 200 195 - MHO_1840 Mycoplasma hominis 5 200 0.000006 24.7573 97
7 194 187 - Lactococcus lactis subsp. lactis KF147 7 195 0.0000001 22.6804 115
1 192 191 - b1861 Escherichia coli 1 200 0.0000003 25.4808 115
1 206 205 - MG358 Mycoplasma genitalium 1 205 <1e-50 65.0485 713
6 202 196 - MS53_0164 Mycoplasma synoviae 6 198 0.0000001 25.1232 112
6 195 189 - MHP7448_0405 Mycoplasma hyopneumoniae 7448 6 214 0.0000002 22.5806 110
7 205 198 - MMOB2700 Mycoplasma mobile 10 204 0.0000000002 26.2136 137
1 202 201 - MYCGA6040 Mycoplasma gallisepticum 1 226 4e-24 31.4159 255
1 206 205 - MYPE2790 Mycoplasma penetrans 1 217 0.00000000000001 27.027 174
1 198 197 - Mycoplasma pulmonis 1 191 0.000000001 25.5 130
External IDs
COG 
COG0632L
EC number 
3.6.1.-
Gene ID 
877275
GI 
13508274
GO 
DNA replication, recombination and repair
Home COG 
L
InterPro 
IPR011132|RuvA-like, C-terminal
InterPro 
IPR012340|Nucleic acid-binding, OB-fold, subgroup
InterPro 
IPR013849|Bacterial DNA recombination protein RuvA, domain I
InterPro 
IPR010994|RuvA domain 2-like
InterPro 
IPR008994|Nucleic acid-binding, OB-fold
InterPro 
IPR003583|Helix-hairpin-helix DNA-binding, class 1
InterPro 
IPR000085|Bacterial DNA recombination protein RuvA
Old MP number 
MP307
Pathway 
transcription, DNA repair, DNA maintenance
PDB homologs 
1hjp_
PDB homologs 
1bdx_A
PDB homologs 
1BVS-A
PDB homologs 
1c7y_A
Pfam 
PF01330
Pfam 
PF07499
PID 
g1673979
RefSeq 
NP_110224.1
Swiss-Prot protein ID 
RUVA_MYCPN
phylomeDB tree 
RUVA_MYCPN
UniProt 
P75243
Transcription
IMAGE BROWSERS

OPERON OP227 (Genomic Overview)
Region:656095-658400

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STRING image

STRING of Mpn535STRING legend

PDB image(s)

1hjp

PDB 1hjp

1bdx

PDB 1bdx

1BVS

PDB 1BVS

1c7y

PDB 1c7y
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