MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene spoT (MPN397)
Name 
spoT
Stable ID 
MPN397
Location 
476470 - 478671 +
Sequence 
    1  ATGTTTTACA ATTGACTTAA ATTATATAAA TTTAGCAAAA TGGCCACTTT AGTTGAAATT
   61  GAACGCGATT TTTTACAAAA AACAGCCCAA AAATTTGCAC CTGAAGTGGT TGCGTTGATT
  121  ACTAAAGCAC TCGATTACTC CAAAAAGTGA CACGGTGAGC AAAAAAGGCT GAGTGGTGAA
  181  CCGTTTTTTA TCCATCCCTT GAGAACAGCA CTGCGCTTAG TGGAGTGAAA CATGGACAGC
  241  AACACCGTGT GTGCTGGTCT GTTACACGAC ATTATTGAAG ATACCCAGGT CACTGAAGCT
  301  GATTTAACTG CCATTTTTGG TAAAGAAATT ACTGATTTAG TGGTAAAAGT TACCAAAATT
  361  ACCAGTGAAT CCAAAAAACA ACGCCAGCTA AACCGAAAGA AAGAAGATTT AAACCTCAAA
  421  AGTTTGGTTA ACATTGCGAT GAGCTCGCAG CAAGAGGTCA ATGCTTTGGT GTTAAAGTTG
  481  GCCGACCGAC TCGACAACAT CTCCTCAATT GAATTTTTAG CAGTCGAAAA ACAAAAGATT
  541  ATTGCTAAAG AAACACTCGA ACTGTATGCC AAGATAGCCG GTCGAATTGG AATGTATCCC
  601  GTTAAAACTC AACTAGCCGA TCTTTCCTTT AAGGTATTAG ATCCAAAAAA CTTTAACAAT
  661  ACGCTGTCCA AGATTAACCA GCAAAAGGTC TTTTATGACA ACGAATGGGG CAACTTTAAA
  721  AAACAGTTGG AAGAGATGCT GGAACAAAAC CAGATTGAAT ACCGCTTAGA AAGTCGAATT
  781  AAAGGCATTT ATTCTACTTA TCAAAAATTA ACCTTTCACG AGCAGAACAT TGCCAAAATC
  841  CACGATCTGT TCGCCATTCG TTTAATTGTG AAGTCAGAGT TGGATTGTTA CCACTTACTT
  901  GGTTTAATCC ACCTCAACTT TACCGTGTTA ATGAAACACT TTAAGGATTA CATAGCATCC
  961  CCCAAACAAA ACTTTTACCA ATCAATCCAC ACGACTGTGC GCTTGAAGGG TTTAAATGTG
 1021  GAAATCCAGA TTAGAACCCA ACGAATGGAT CATGTGAGCA AGTACGGTTT TGCTAGCCAC
 1081  TGGATTTACA AAGAGAAAAA GGAAGGGTTA TTGGCAAGTG CTTTACAAGT AAATTACTTA
 1141  AACAGTAAAC AAATGCATTC GCGCGATTTT TTTAAACGAA TCTTTGGTAC TGATATTATT
 1201  AAGGTTAATG TAAGTTCCGA TAACGAACCT AACATAGTCA AAAAACTCAA TGTTGAAAGT
 1261  AACAGCAAGT TGCTCGATAT TGCTTATGAG TTGTATCCCA AACAGTTCAA TAAATTAGAA
 1321  AAAATCAAAC TCGATGGGGT TGAGGTTATG TCGTTTGACG TAACTGCCGA AAACGAAATG
 1381  GTAATTGAGT TTTGTTTTGG TAAAACCAAT AACCTCAAAC GGCGTTGGTT ACGTTATATG
 1441  AATAACCACG TATTTCGCGA ACGGGTTAAA AAGGATTTAA ACAAGTTAAA GAAAGCGGTT
 1501  AAGTACAGTG AACTACCTCT ATACGAAAAG GCCTTGGAAG AGTTGCACTT AAAGCTAGCT
 1561  GATGAAACCC AGATTAAACA ACGCTTAAAT GCTTTAGGGA TCAAAAAACT GACAGAGTTC
 1621  TTGGAATTAA TCGAATACCC CCACTTCCCT AAAAATGAGC ATTTGTACTT TTTAGCTAGT
 1681  AACAATCAGA AGTGAAGGGA ATTGATTAAA CCCATTAAGT TCGCTTTATC ACAAGCTGTG
 1741  TTCCAAAACT CTTACTTTGA ACAAATTGAG GGAATTTACA TCACCAAAAT TGTGATTGAA
 1801  ACCTGTTGCA CAAAGATTCC TGACATGCCA GAACAAGTTA TTGGCATCTT AATGAAAAAC
 1861  ATTCTCAGGG TACACCTTCA TGATTGTAGG GAATTAGCTA ATCAAAAGCA ACCCAAAATT
 1921  ATTCCACTTT ATTGAAATGC ACACCAATTA AAGATGCGAC CACGTAAATT CCGCTGTCAA
 1981  ATTAACATTC GCGGTGTATG GAGTGAAACA ACGGTCAATA AAATTGTTCA AACCATTATT
 2041  GAAGGTGATA GCTATTTAGA ACGAATTATT CCCAAGATCG ATAAACAAAA AGATGAGTTT
 2101  GAGCTCAACA TTACTATGTT TATCGACAAC TATCACCAAC TAATCACAAT TATGGAGCAG
 2161  ATTACTACTA AGAATATTAG CTACGTTTGA AAGTACCTTT AA
Download Sequence
Operon 
OP162
Operon location 
476485 - 478620
Protein (mpn397)
Name 
Probable guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)
Stable ID 
Mpn397
Molecular Weight 
80630
Isoelectric Point 
10
Localization 
Cytoplasm
Comment -
Sequence 
MFYNWLKLYKFSKMATLVEIERDFLQKTAQKFAPEVVALITKALDYSKKWHGEQKRLSGEPFFIHPLRTALRLVEWNMDS
NTVCAGLLHDIIEDTQVTEADLTAIFGKEITDLVVKVTKITSESKKQRQLNRKKEDLNLKSLVNIAMSSQQEVNALVLKL
ADRLDNISSIEFLAVEKQKIIAKETLELYAKIAGRIGMYPVKTQLADLSFKVLDPKNFNNTLSKINQQKVFYDNEWGNFK
KQLEEMLEQNQIEYRLESRIKGIYSTYQKLTFHEQNIAKIHDLFAIRLIVKSELDCYHLLGLIHLNFTVLMKHFKDYIAS
PKQNFYQSIHTTVRLKGLNVEIQIRTQRMDHVSKYGFASHWIYKEKKEGLLASALQVNYLNSKQMHSRDFFKRIFGTDII
KVNVSSDNEPNIVKKLNVESNSKLLDIAYELYPKQFNKLEKIKLDGVEVMSFDVTAENEMVIEFCFGKTNNLKRRWLRYM
NNHVFRERVKKDLNKLKKAVKYSELPLYEKALEELHLKLADETQIKQRLNALGIKKLTEFLELIEYPHFPKNEHLYFLAS
NNQKWRELIKPIKFALSQAVFQNSYFEQIEGIYITKIVIETCCTKIPDMPEQVIGILMKNILRVHLHDCRELANQKQPKI
IPLYWNAHQLKMRPRKFRCQINIRGVWSETTVNKIVQTIIEGDSYLERIIPKIDKQKDEFELNITMFIDNYHQLITIMEQ
ITTKNISYVWKYL
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation SLVNIAmSSQQEVNALVLK 141 160 M
Oxidation QLEEmLEQNQIEYR 242 256 M
Oxidation QLEEmLEQNQIEYRLESR 242 260 M
GENE/PROTEIN spoT (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
17-214 SSF109604 (n.a.) NULL 0
43-732 TIGR00691 (IPR004811) RelA/SpoT protein Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0015969'>'guanosine' == '' ? '': 'guanosine'; 'tetraphosphate' == '' ? '': 'tetraphosphate'; 'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0015969)

0
58-176 SM00471 (IPR003607) Metal-dependent phosphohydrolase, HD domain Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003824'>'catalytic' == '' ? '': 'catalytic'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003824)

0.000009
63-166 PF01966 (IPR006674) Metal-dependent phosphohydrolase, HD subdomain 0.000042
139-733 PTHR21262 (n.a.) NULL 9.99967e-42
215-388 SSF81301 (n.a.) NULL 0
258-366 PF04607 (IPR007685) RelA/SpoT Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0015969'>'guanosine' == '' ? '': 'guanosine'; 'tetraphosphate' == '' ? '': 'tetraphosphate'; 'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0015969)

5e-28
258-367 SM00954 (IPR007685) RelA/SpoT Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0015969'>'guanosine' == '' ? '': 'guanosine'; 'tetraphosphate' == '' ? '': 'tetraphosphate'; 'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0015969)

4.30058e-42
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
25 368 343 - b3650 Escherichia coli 7 346 <1e-50 34.3931 539
77 646 569 - b2784 Escherichia coli 70 658 6e-33 23.5679 342
40 646 606 - MCAP_0496 Mycoplasma capricolum subsp. capricolum 38 662 <1e-50 31.2112 661
43 733 690 - MYCGA1860 Mycoplasma gallisepticum 33 722 <1e-50 37.1631 1231
14 733 719 - MG278 Mycoplasma genitalium 1 720 <1e-50 70.9722 2745
40 646 606 - MSC_0475 Mycoplasma mycoides subsp. mycoides SC 38 662 <1e-50 30.6028 648
16 641 625 - MYPE5280 Mycoplasma penetrans 7 624 <1e-50 32.6019 835
15 365 350 - Lactococcus lactis subsp. lactis KF147 10 347 <1e-50 35.3276 567
24 380 356 - LIC_11012 Leptospira interrogans serovar Copenhage 13 364 <1e-50 39.9441 689
37 367 330 - Rv2583c Mycobacterium tuberculosis 80 403 <1e-50 37.0482 566
38 370 332 - Caulobacter crescentus NA1000 40 368 <1e-50 36.6864 576
25 367 342 - Bacillus subtilis subsp. subtilis 13 350 <1e-50 38.8102 604
25 367 342 - Bacillus subtilis subsp. subtilis 13 350 <1e-50 38.8102 604
249 350 101 - Bacillus subtilis subsp. subtilis 71 185 0.000004 31.0345 113
249 350 101 - Bacillus subtilis subsp. subtilis 49 163 0.000005 31.0345 112
External IDs
COG 
COG0317TK
EC number 
3.1.7.2
Gene ID 
877121
GI 
13508136
GO 
Signal transduction mechanisms/ Nucleotide transport and metabolism
Home COG 
TF
InterPro 
IPR003607|Metal-dependent phosphohydrolase, HD region
InterPro 
IPR008921|DNA polymerase III clamp loader subunit, C-terminal
InterPro 
IPR007685|RelA/SpoT
InterPro 
IPR006674|Metal-dependent phosphohydrolase, HD region, subdomain
InterPro 
IPR004811|RelA/SpoT protein
Old MP number 
MP441
Pathway 
Regulation
PDB homologs 
1vj7_A
Pfam 
PF04607
Pfam 
PF01966
PID 
g1674128
RefSeq 
NP_110085.1
Swiss-Prot protein ID 
SPOT_MYCPN
phylomeDB tree 
SPOT_MYCPN
UniProt 
P75386
Transcription
IMAGE BROWSERS

OPERON OP162 (Genomic Overview)
Region:476485-478620

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STRING image

STRING of Mpn397STRING legend

PDB image(s)

1vj7

PDB 1vj7
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