MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene pdhC (MPN391)
Name 
pdhC
Stable ID 
MPN391
Location 
467847 - 469055 -
Sequence 
    1  ATGGCAAATG AGTTTAAGTT CACCGATGTT GGTGAGGGCT TACATGAGGG TAAAGTAACT
   61  GAAATCCTCA AAAAAGTGGG CGATACGATC AAGGTCGATG AAGCCCTTTT TGTAGTGGAA
  121  ACCGATAAGG TAACCACCGA ACTTCCATCC CCTTATGCTG GGGTTATTAC CGCCATTACC
  181  ACTAATGTTG GTGATGTGGT GCACATTGGT CAGGTGATGG CCGTTATTGA TGATGGCGCT
  241  GGTGCTGCTG CACCTGCTGC GCCCCAACCA GTATCTGCAC CAGCTCCTGC CCCAACCCCA
  301  ACATTTACCC CAACACCAGC ACCTGTAACC ACCGAACCAG TAGTGGAAGA GGCGGGTGCC
  361  TCGGTAGTGG GTGAAATTAA GGTATCGAAC AGTGTGTTTC CTATTTTTGG TGTGCAGCCA
  421  AGTGCGCCCC AACCAACACC AGCTCCTGTA GTACAACCTA CATCCGCTCC AACTCCCACT
  481  CCAGCTCCAG CATCTGCAGC AGCACCTAGT GGTGAGGAAA CGATTGCGAT CACGACAATG
  541  CGTAAAGCAA TTGCTGAAGC AATGGTGAAA TCACACGAAA ACATTCCCGC TACGATTCTC
  601  ACCTTCTATG TTAACGCTAC TAAGTTAAAG CAGTACCGTG AGAGTGTTAA CGGCTTAGCT
  661  TTAAGCAAGT ACAACATGAA GATTTCCTTC TTTGCTTTCT TTGTTAAAGC AATTGTTAAT
  721  GCTTTGAAGA AGTTTCCTGT TTTCAATGGT CGTTATGACA AGGAACGCAA CCTAATTGTG
  781  TTAAACAAGG ATGTTAACGT AGGTATTGCC GTGGACACTC CCGATGGTCT GATTGTGCCT
  841  AACATTAAGC AAGCACAAAC GAAGTCGGTA GTCGACATTG CCAAGGACAT TGTTGATCTT
  901  GCTAACCGCG CCCGCAGTAA GCAAATTAAG CTTCCTGATT TAAGTAAGGG AACGATCTCG
  961  GTAACTAACT TTGGTTCTTT AGGCGCTGCT TTTGGTACCC CGATTATTAA GCACCCGGAA
 1021  ATGTGTATTG TCGCTACCGG TAACATGGAA GAACGTGTTG TGCGTGCTGA AGGTGGGGTA
 1081  GCCGTTCATA CCATCCTACC GTTAACAATT GCTGCCGACC ACCGCTGGGT CGATGGCGCT
 1141  GATGTGGGTC GCTTTGGTAA GGAAATTGCC AAGCAAATCG AAGAATTAAT TGATTTAGAA
 1201  GTAGCTTAG
Download Sequence
Operon 
OP439
Operon location 
464000 - 469068
Protein (mpn391)
Name 
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (E2) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex)
Stable ID 
Mpn391
Molecular Weight 
44220
Isoelectric Point 
5
Localization 
Cytoplasm
Comment -
Sequence 
MANEFKFTDVGEGLHEGKVTEILKKVGDTIKVDEALFVVETDKVTTELPSPYAGVITAITTNVGDVVHIGQVMAVIDDGA
GAAAPAAPQPVSAPAPAPTPTFTPTPAPVTTEPVVEEAGASVVGEIKVSNSVFPIFGVQPSAPQPTPAPVVQPTSAPTPT
PAPASAAAPSGEETIAITTMRKAIAEAMVKSHENIPATILTFYVNATKLKQYRESVNGLALSKYNMKISFFAFFVKAIVN
ALKKFPVFNGRYDKERNLIVLNKDVNVGIAVDTPDGLIVPNIKQAQTKSVVDIAKDIVDLANRARSKQIKLPDLSKGTIS
VTNFGSLGAAFGTPIIKHPEMCIVATGNMEERVVRAEGGVAVHTILPLTIAADHRWVDGADVGRFGKEIAKQIEELIDLE
VA
Post translational modifications
Modification Modified sequence Relative start Relative end Amino acid
Oxidation kAIAEAmVK 182 191 M
Oxidation KAIAEAmVk 182 191 M
Oxidation kAIAEAmVk 182 191 M
Oxidation KAIAEAmVK 182 191 M
Oxidation AIAEAmVK 183 191 M
Oxidation HPEmcIVATGNmEEr 338 353 M
Oxidation HPEMcIVATGNmEER 338 353 M
Oxidation HPEmcIVATGNmEER 338 353 M
Oxidation HPEmcIVATGNMEEr 338 353 M
Oxidation HPEmcIVATGNMEER 338 353 M
Oxidation HPEMcIVATGNmEEr 338 353 M
GENE/PROTEIN pdhC (Domains Overview)
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Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-94 G3DSA:2.40.50.100 (n.a.) NULL 8.5e-26
1-98 SSF51230 (IPR011053) Single hybrid motif 4.40001e-26
3-76 PS50968 (IPR000089) Biotin/lipoyl attachment 0
3-76 PF00364 (IPR000089) Biotin/lipoyl attachment 7.3e-19
4-374 PTHR23151 (n.a.) NULL 0
4-374 PTHR23151:SF19 (n.a.) NULL 0
27-56 PS00189 (IPR003016) 2-oxo acid dehydrogenase, lipoyl-binding site 0
158-401 SSF52777 (n.a.) NULL 0
160-396 G3DSA:3.30.559.10 (n.a.) NULL 0
171-396 PF00198 (IPR001078) 2-oxoacid dehydrogenase acyltransferase, catalytic Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008152'>'metabolic' == '' ? '': 'metabolic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0008152)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0008415'>'acyltransferase' == '' ? '': 'acyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0008415)

0
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
172 381 209 - b0727 Escherichia coli 176 383 3e-27 30.3318 290
207 385 178 - b0115 Escherichia coli 435 614 1e-25 30 276
13 77 64 - b0115 Escherichia coli 114 178 0.0000000003 44.6154 276
1 75 74 - b0115 Escherichia coli 1 73 0.0000000003 41.3333 276
13 77 64 - b0115 Escherichia coli 215 279 0.000000002 40 276
172 394 222 - MAG0950 Mycoplasma agalactiae 13 236 2e-40 38.3929 399
6 71 65 - MAG4910 Mycoplasma agalactiae 5 70 0.0000000000002 48.4848 164
177 395 218 - MCJ_000690 Mycoplasma conjunctivae 83 301 1.96182e-44 39.2694 432
4 78 74 - MCJ_000700 Mycoplasma conjunctivae 3 77 1e-19 53.3333 219
175 385 210 - MCAP_0227 Mycoplasma capricolum subsp. capricolum 213 422 2e-37 37.4408 373
6 78 72 - MCAP_0227 Mycoplasma capricolum subsp. capricolum 5 77 0.000000000000002 49.3151 373
6 78 72 - MCAP_0228 Mycoplasma capricolum subsp. capricolum 5 77 7e-16 52.0548 187
177 396 219 - MYCGA4830 Mycoplasma gallisepticum 215 435 <1e-50 56.5611 676
4 77 73 - MYCGA4830 Mycoplasma gallisepticum 3 76 4e-22 62.1622 676
1 402 401 - MG272 Mycoplasma genitalium 1 384 <1e-50 66.6667 1318
177 395 218 - MHP7448_0506 Mycoplasma hyopneumoniae 7448 80 298 1.4013e-45 40.1826 443
4 78 74 - MHP7448_0507 Mycoplasma hyopneumoniae 7448 3 77 6e-18 50.6667 204
177 394 217 - MMOB5810 Mycoplasma mobile 228 445 5.60519e-45 40.367 437
4 78 74 - MMOB5810 Mycoplasma mobile 3 77 1e-19 56 437
4 78 74 - MMOB5800 Mycoplasma mobile 3 77 2e-20 57.3333 226
173 385 212 - MSC_0267 Mycoplasma mycoides subsp. mycoides SC 201 412 2e-35 36.1502 356
6 78 72 - MSC_0267 Mycoplasma mycoides subsp. mycoides SC 5 77 0.000000000000003 49.3151 356
6 78 72 - MSC_0268 Mycoplasma mycoides subsp. mycoides SC 5 77 8e-16 52.0548 187
171 396 225 - MYPE5100 Mycoplasma penetrans 248 473 <1e-50 42.9204 521
5 78 73 - MYPE5100 Mycoplasma penetrans 4 77 4e-19 56.7568 521
25 71 46 - Lactococcus lactis subsp. lactis KF147 103 149 0.000003 46.8085 107
171 379 208 - Lactococcus lactis subsp. lactis KF147 300 508 6e-32 34.2857 328
1 77 76 - Lactococcus lactis subsp. lactis KF147 1 77 0.00000000006 37.6623 328
5 70 65 - Lactococcus lactis subsp. lactis KF147 111 176 0.0000000001 42.4242 328
1 77 76 - LIC_12476 Leptospira interrogans serovar Copenhage 1 77 0.00000000009 36.3636 287
172 395 223 - LIC_12476 Leptospira interrogans serovar Copenhage 192 413 6e-27 30.0885 287
171 395 224 - MS53_0274 Mycoplasma synoviae 63 287 <1e-50 40.4444 464
5 78 73 - MS53_0275 Mycoplasma synoviae 4 77 8e-20 56.7568 220
190 395 205 - Rv2215 Mycobacterium tuberculosis 331 544 6e-26 36.4486 279
1 78 77 - Rv2215 Mycobacterium tuberculosis 1 78 0.0000000000001 48.7179 279
9 76 67 - Rv2215 Mycobacterium tuberculosis 128 195 0.00000000003 47.0588 279
184 399 215 - Rv2495c Mycobacterium tuberculosis 177 393 3e-23 31.982 256
3 77 74 - Rv2495c Mycobacterium tuberculosis 8 82 0.000000001 41.3333 256
171 389 218 - Rv1248c Mycobacterium tuberculosis 101 331 0.0000000000002 29.2373 171
175 399 224 - Caulobacter crescentus NA1000 205 426 1e-28 34.2222 302
172 395 223 - Caulobacter crescentus NA1000 173 394 1e-28 31.5556 301
10 76 66 - Caulobacter crescentus NA1000 9 75 0.0000002 43.2836 301
171 398 227 - Bacillus subtilis subsp. subtilis 193 418 2e-35 38.4279 363
171 398 227 - Bacillus subtilis subsp. subtilis 193 418 3e-35 37.9913 361
177 380 203 - Bacillus subtilis subsp. subtilis 217 419 7e-35 35.7843 358
1 77 76 - Bacillus subtilis subsp. subtilis 1 77 0.0000000003 37.6623 358
177 380 203 - Bacillus subtilis subsp. subtilis 217 419 7e-35 35.7843 358
1 77 76 - Bacillus subtilis subsp. subtilis 1 77 0.0000000003 37.6623 358
173 395 222 - Bacillus subtilis subsp. subtilis 172 392 9e-30 33.6323 314
173 395 222 - Bacillus subtilis subsp. subtilis 172 392 2e-29 34.0807 311
173 395 222 - Bacillus subtilis subsp. subtilis 188 409 8e-23 29.3333 254
4 78 74 - Bacillus subtilis subsp. subtilis 3 77 0.00000001 33.3333 254
173 381 208 - Bacillus subtilis subsp. subtilis 188 395 1e-22 29.3839 253
4 78 74 - Bacillus subtilis subsp. subtilis 3 77 0.00000001 33.3333 253
177 395 218 - Mycoplasma pulmonis 90 308 <1e-50 40.6393 454
4 78 74 - Mycoplasma pulmonis 3 77 3e-20 56 225
External IDs
COG 
COG0508C
EC number 
2.3.1.12
Gene ID 
877106
GI 
13508130
GO 
Energy production and conversion
Home COG 
C
InterPro 
IPR003016|2-oxo acid dehydrogenase, lipoyl-binding site
InterPro 
IPR011053|Single hybrid motif
InterPro 
IPR000089|Biotin/lipoyl attachment
InterPro 
IPR001078|Catalytic domain of components of various dehydrogenase complexes
Old MP number 
MP447
Pathway 
Metabolism energy
PDB homologs 
1c4t_A
PDB homologs 
1e2o_
PDB homologs 
1scz_A
Pfam 
PF00198
Pfam 
PF00364
PID 
g1674135
RefSeq 
NP_110079.1
Swiss-Prot protein ID 
ODP2_MYCPN
phylomeDB tree 
ODP2_MYCPN
UniProt 
P75392
Transcription
IMAGE BROWSERS

OPERON OP439 (Genomic Overview)
Region:464000-469068

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STRING image

STRING of Mpn391STRING legend

PDB image(s)

1c4t

PDB 1c4t

1e2o

PDB 1e2o

1scz

PDB 1scz
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