MyMpn Project

Name	ptxA
Stable ID	MPN372
Location	444341 - 446116 +
Sequence	1 ATGCCAAATC CTGTTAGATT TGTTTACCGT GTTGATTTGA GAAGCCCTGA AGAAATTTTT 61 GAACATGGCT TTTCAACTTT AGGTGATGTG AGAAATTTCT TTGAACACAT TCTCTCCACT 121 AATTTTGGTA GAAGCTATTT TATTTCCACT TCAGAAACAC CCACAGCAGC TATTCGCTTC 181 TTTGGTAGCT GGTTACGGGA ATATGTACCA GAGCACCCCA GAAGGGCTTA CTTATATGAA 241 ATTCGTGCCG ACCAACACTT TTACAATGCC CGCGCCACTG GGGAGAACTT GTTAGATTTA 301 ATGCGTCAAA GACAAGTAGT ATTTGACTCT GGTGATCGAG AAATGGCACA AATGGGAATT 361 AGAGCTTTAC GCACTTCCTT TGCGTATCAA CGTGAATGGT TTACCGATGG TCCAATTGCA 421 GCAGCTAATG TCCGTAGTGC TTGACTAGTA GATGCTGTTC CCGTTGAACC TGGTCATGCT 481 CACCACCCGG CTGGTCGTGT TGTAGAGACT ACTAGAATTA ATGAACCGGA AATGCACAAC 541 CCTCATTATC AAGAGCTGCA AACCCAAGCC AATGATCAAC CATGATTGCC AACACCAGGA 601 ATAGCTACTC CTGTACATTT ATCAATTCCC CAAGCAGCTT CCGTTGCTGA TGTTTCGGAA 661 GGTACTTCCG CTTCGCTATC GTTTGCGTGC CCTGATTGAA GTCCACCTTC TAGTAATGGT 721 GAAAATCCGC TAGACAAATG CATTGCGGAA AAGATTGATA ACTATAACCT ACAATCCTTA 781 CCACAGTACG CTAGCAGTGT AAAGGAACTG GAAGATACAC CAGTATACCT AAGGGGAATT 841 AAAACGCAAA AAACCTTTAT GTTACAAGCA GATCCGCAAA ATAACAATGT CTTTTTGGTC 901 GAAGTAAACC CCAAACAAAA GTCCAGCTTT CCCCAAACCA TCTTCTTTTG GGATGTTTAT 961 CAACGAATTT GTCTCAAGGA TTTAACTGGT GCACAAATCA GTCTTTCGCT TACTGCCTTT 1021 ACTACTCAGT ATGCTGGTCA GCTCAAAGTG CACCTTAGTG TTAGCGCGGT TAATGCCGTG 1081 AACCAAAAGT GAAAAATGAC ACCGCAAGAC ATTGCAATAA CTCAGTTTCG GGTCTCCTCT 1141 GAACTGTTAG GTCAAACTGA AAATGGCTTG TTCTGAAATA CCAAGAGTGG TGGTTCACAA 1201 CACGATTTGT ATGTATGTCC TTTGAAAAAT CCACCTAGTG ATTTGGAAGA ATTACAAATA 1261 ATTGTTGATG AATGTACTAC CCATGCGCAG TTTGTTACTA TGCGTGCAGC TAGCACCTTC 1321 TTTGTTGATG TTCAGCTAGG CTGGTATTGA AGGGGTTATT ACTATACCCC ACAATTAAGT 1381 GGTTGATCTT ATCAGATGAA AACACCAGAT GGACAGATAT TCTATGATCT AAAAACTTCG 1441 AAAATCTTCT TTGTCCAGGA CAACCAAAAC GTGTTCTTTC TCCATAATAA ACTCAACAAA 1501 CAAACTGGTT ACAGCTGGGA TTGAGTAGAA TGGCTAAAAC ATGACATGAA TGAGGACAAA 1561 GACGAAAACT TTAAATGGTA CTTTTCGCGT GATGACCTTA CCATTCCTTC CGTTGAAGGG 1621 CTTAACTTCC GCCACATTCG CTGTTACGCT GACAACCAGC AGTTAAAGGT GATCATAAGC 1681 GGTTCACGTT GGGGCGGTTG GTACTCCACT TACGATAAAG TTGAAAGTAA TGTCGAAGAT 1741 AAGATTTTGG TCAAAGATGG TTTTGATCGC TTTTAG
Download Sequence
Operon	OP149
Operon location	444330 - 446500

MPNPVRFVYRVDLRSPEEIFEHGFSTLGDVRNFFEHILSTNFGRSYFISTSETPTAAIRFFGSWLREYVPEHPRRAYLYE

IRADQHFYNARATGENLLDLMRQRQVVFDSGDREMAQMGIRALRTSFAYQREWFTDGPIAAANVRSAWLVDAVPVEPGHA

HHPAGRVVETTRINEPEMHNPHYQELQTQANDQPWLPTPGIATPVHLSIPQAASVADVSEGTSASLSFACPDWSPPSSNG

ENPLDKCIAEKIDNYNLQSLPQYASSVKELEDTPVYLRGIKTQKTFMLQADPQNNNVFLVEVNPKQKSSFPQTIFFWDVY

QRICLKDLTGAQISLSLTAFTTQYAGQLKVHLSVSAVNAVNQKWKMTPQDIAITQFRVSSELLGQTENGLFWNTKSGGSQ

HDLYVCPLKNPPSDLEELQIIVDECTTHAQFVTMRAASTFFVDVQLGWYWRGYYYTPQLSGWSYQMKTPDGQIFYDLKTS

KIFFVQDNQNVFFLHNKLNKQTGYSWDWVEWLKHDMNEDKDENFKWYFSRDDLTIPSVEGLNFRHIRCYADNQQLKVIIS

GSRWGGWYSTYDKVESNVEDKILVKDGFDRF

Name	ADP-ribosylating toxin CARDS (EC 2.4.2.-) (CARDX TX) (ADP-ribosyltransferase CARDS)
Stable ID	Mpn372
Molecular Weight	65010
Isoelectric Point	6
Localization	Cytoplasm
Comment	Binds to human surfactant protein-A (hSP-A). INFECTION AND IMMUNITY, May 2005, p. 2828–2834
Sequence	MPNPVRFVYRVDLRSPEEIFEHGFSTLGDVRNFFEHILSTNFGRSYFISTSETPTAAIRFFGSWLREYVPEHPRRAYLYE IRADQHFYNARATGENLLDLMRQRQVVFDSGDREMAQMGIRALRTSFAYQREWFTDGPIAAANVRSAWLVDAVPVEPGHA HHPAGRVVETTRINEPEMHNPHYQELQTQANDQPWLPTPGIATPVHLSIPQAASVADVSEGTSASLSFACPDWSPPSSNG ENPLDKCIAEKIDNYNLQSLPQYASSVKELEDTPVYLRGIKTQKTFMLQADPQNNNVFLVEVNPKQKSSFPQTIFFWDVY QRICLKDLTGAQISLSLTAFTTQYAGQLKVHLSVSAVNAVNQKWKMTPQDIAITQFRVSSELLGQTENGLFWNTKSGGSQ HDLYVCPLKNPPSDLEELQIIVDECTTHAQFVTMRAASTFFVDVQLGWYWRGYYYTPQLSGWSYQMKTPDGQIFYDLKTS KIFFVQDNQNVFFLHNKLNKQTGYSWDWVEWLKHDMNEDKDENFKWYFSRDDLTIPSVEGLNFRHIRCYADNQQLKVIIS GSRWGGWYSTYDKVESNVEDKILVKDGFDRF

Modification	Modified sequence	Relative start	Relative end	Amino acid
Oxidation	ATGENLLDLmr	92	103	M
Oxidation	ATGENLLDLmR	92	103	M
Oxidation	EmAQmGIR	114	122	M
Oxidation	TFmLQADPQNNNVFLVEVNPk	285	306	M
Oxidation	TFmLQADPQNNNVFLVEVNPK	285	306	M
Oxidation	mTPQDIAITQFR	366	378	M
Oxidation	mTPQDIAITQFr	366	378	M
Oxidation	GYYYTPQLSGWSYQmK	452	468	M

Location (aa)	Name (InterPro ID)	Description	GO terms	Sequence	Evalue
3-234	PF02917 (IPR003898)	Bordetella pertussis toxin A	Biological Process: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009405'>'pathogenesis' == '' ? '': 'pathogenesis'; ('GO' == '' ? '': 'GO';:0009405) Cellular Component: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005576'>'extracellular' == '' ? '': 'extracellular'; 'region' == '' ? '': 'region'; ('GO' == '' ? '': 'GO';:0005576) Molecular Function: <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0003950'>'NAD' == '' ? '': 'NAD';+ 'ADP' == '' ? '': 'ADP';-'ribosyltransferase' == '' ? '': 'ribosyltransferase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0003950)		0
3-252	G3DSA:3.90.210.10 (n.a.)	NULL			0
3-256	SSF56399 (IPR008893)	WGR domain			0

Protein Start	Protein End	Hit Size	Orthologous	Organism	Orthologous Start	Orthologous End	Evalue	Identity	Score	Alignment
4	203	199	- MYPE9110	Mycoplasma penetrans	22	226	0.000000000008	26.7943	154

EC number	2.4.2.-
Gene ID	877260
GI	13508111
GO	Defense mechanisms
Home COG	V
Old MP number	MP464
Pathway	Virulence
PDB homologs	1pto_A
PDB homologs	1bcp_A
PDB homologs	1prt_A
PDB homologs	1BCP-A
Pfam	PF02917
PID	g1674154
RefSeq	NP_110060.1
Swiss-Prot protein ID	CARDS_MYCPN
phylomeDB tree	No orthologous found
UniProt	P75409