MyMpn
The Mycoplasma pneumoniae database
 
e.g Mpn001 or dnaN or polymerase
Gene mthfs (MPN348)
Name 
mthfs
Stable ID 
MPN348
Location 
416070 - 416564 +
Sequence 
    1  ATGGACAAAA ATGCCTTAAG AAAACAAATT CTGCAAAAAA GAATGGCATT AAGTACCATT
   61  GAAAAAAGTC ACTTAGATCA AAAGATTAAT CAAAAATTAG TTGCTTTTTT AACTCCTAAG
  121  CCATGCATTA AAACAATTGC ACTTTATGAA CCCATTAAAA ATGAGGTTAC TTTTGTTGAC
  181  TTCTTCTTTG AGTTTTTAAA GATTAACCAA ATAAGAGCTG TTTACCCCAA GGTAATAAGT
  241  GATACCGAAA TTATCTTTAT TGATCAGGAG ACAAATACAT TCGAACCTAA TCAAATAGAC
  301  TGCTTCCTAA TACCATTGGT AGGCTTTAAT AAAGACAATT ACCGTCTAGG CTTTGGCAAG
  361  GGCTATTATG ACCGTTATTT AATGCAATTA ACTAGACAAC AACCTAAAAT AGGAATAGCG
  421  TACAGTTTCC AAAAAGGTGA TTTTTTAGCC GATCCTTGGG ATGTACAACT AGACTTAATT
  481  ATTAATGATG AATAG
Download Sequence
Operon 
OP138
Operon location 
415152 - 418600
Protein (mpn348)
Name 
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)
Stable ID 
Mpn348
Molecular Weight 
18040
Isoelectric Point 
7
Localization 
Cytoplasm
Comment -
Sequence 
MDKNALRKQILQKRMALSTIEKSHLDQKINQKLVAFLTPKPCIKTIALYEPIKNEVTFVDFFFEFLKINQIRAVYPKVIS
DTEIIFIDQETNTFEPNQIDCFLIPLVGFNKDNYRLGFGKGYYDRYLMQLTRQQPKIGIAYSFQKGDFLADPWDVQLDLI
INDE
Post translational modifications
No post translational modifications were found
GENE/PROTEIN mthfs (Domains Overview)
Click on the features to jump to domain info

 ExportIMG
Domains (InterProScan)
Location (aa) Name (InterPro ID) Description GO terms Sequence Evalue
1-161 PTHR23407:SF1 (IPR002698) 5-formyltetrahydrofolate cyclo-ligase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009396'>'folic' == '' ? '': 'folic'; 'acid' == '' ? '': 'acid'; 'and' == '' ? '': 'and'; 'derivative' == '' ? '': 'derivative'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0030272'>5-'formyltetrahydrofolate' == '' ? '': 'formyltetrahydrofolate'; 'cyclo' == '' ? '': 'cyclo';-'ligase' == '' ? '': 'ligase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0030272)

3.30001e-17
1-161 PTHR23407 (n.a.) NULL 3.30001e-17
1-163 G3DSA:3.40.50.10420 (IPR002698) 5-formyltetrahydrofolate cyclo-ligase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009396'>'folic' == '' ? '': 'folic'; 'acid' == '' ? '': 'acid'; 'and' == '' ? '': 'and'; 'derivative' == '' ? '': 'derivative'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0030272'>5-'formyltetrahydrofolate' == '' ? '': 'formyltetrahydrofolate'; 'cyclo' == '' ? '': 'cyclo';-'ligase' == '' ? '': 'ligase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0030272)

3.6e-39
1-164 SSF100950 (n.a.) NULL 4.80001e-41
1-164 PIRSF006806 (IPR002698) 5-formyltetrahydrofolate cyclo-ligase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009396'>'folic' == '' ? '': 'folic'; 'acid' == '' ? '': 'acid'; 'and' == '' ? '': 'and'; 'derivative' == '' ? '': 'derivative'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0030272'>5-'formyltetrahydrofolate' == '' ? '': 'formyltetrahydrofolate'; 'cyclo' == '' ? '': 'cyclo';-'ligase' == '' ? '': 'ligase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0030272)

0
3-162 PF01812 (IPR002698) 5-formyltetrahydrofolate cyclo-ligase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009396'>'folic' == '' ? '': 'folic'; 'acid' == '' ? '': 'acid'; 'and' == '' ? '': 'and'; 'derivative' == '' ? '': 'derivative'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0030272'>5-'formyltetrahydrofolate' == '' ? '': 'formyltetrahydrofolate'; 'cyclo' == '' ? '': 'cyclo';-'ligase' == '' ? '': 'ligase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0030272)

4e-36
3-163 TIGR02727 (IPR002698) 5-formyltetrahydrofolate cyclo-ligase Biological Process:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0009396'>'folic' == '' ? '': 'folic'; 'acid' == '' ? '': 'acid'; 'and' == '' ? '': 'and'; 'derivative' == '' ? '': 'derivative'; 'biosynthetic' == '' ? '': 'biosynthetic'; 'process' == '' ? '': 'process'; ('GO' == '' ? '': 'GO';:0009396)

Molecular Function:
<'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0005524'>'ATP' == '' ? '': 'ATP'; 'binding' == '' ? '': 'binding'; ('GO' == '' ? '': 'GO';:0005524) <'A' == '' ? '': 'A'; 'class' == '' ? '': 'class';=''result' == '' ? '': 'result';' 'target' == '' ? '': 'target';='_'blank' == '' ? '': 'blank';' 'href' == '' ? '': 'href';=''http' == '' ? '': 'http';://'amigo' == '' ? '': 'amigo';.'geneontology' == '' ? '': 'geneontology';.'org' == '' ? '': 'org';/'cgi' == '' ? '': 'cgi';-'bin' == '' ? '': 'bin';/'amigo' == '' ? '': 'amigo';/'term' == '' ? '': 'term';-'details' == '' ? '': 'details';.'cgi' == '' ? '': 'cgi';?'term' == '' ? '': 'term';='GO' == '' ? '': 'GO';:0030272'>5-'formyltetrahydrofolate' == '' ? '': 'formyltetrahydrofolate'; 'cyclo' == '' ? '': 'cyclo';-'ligase' == '' ? '': 'ligase'; 'activity' == '' ? '': 'activity'; ('GO' == '' ? '': 'GO';:0030272)

2.8e-27
Protein Homology (BLASTP results)
Protein Start Protein End Hit Size Orthologous Organism Orthologous Start Orthologous End Evalue Identity Score Alignment
1 163 162 - MAG5750 Mycoplasma agalactiae 1 179 0.000000000000007 30.9392 173
3 164 161 - Caulobacter crescentus NA1000 22 204 0.000000003 28.6486 130
7 157 150 - Lactococcus lactis subsp. lactis KF147 8 165 0.0000000001 29.878 140
69 129 60 - Bacillus subtilis subsp. subtilis 91 146 0.0000002 36.0656 117
69 129 60 - Bacillus subtilis subsp. subtilis 91 146 0.0000002 36.0656 117
1 161 160 - MG245 Mycoplasma genitalium 2 162 <1e-50 60.2484 521
1 163 162 - MCAP_0467 Mycoplasma capricolum subsp. capricolum 1 179 0.00000000000004 32.2581 168
1 164 163 - MSC_0503 Mycoplasma mycoides subsp. mycoides SC 1 180 0.00000000001 27.4725 146
97 160 63 - MYCGA3790 Mycoplasma gallisepticum 113 177 0.000000000004 46.1538 150
External IDs
EC number 
6.3.3.2
Gene ID 
876747
GI 
13508087
GO 
Coenzyme metabolism
Home COG 
H
InterPro 
IPR002698|5-formyltetrahydrofolate cyclo-ligase
Old MP number 
MP488
Pathway 
Biosynthesis of cofactors, prosthetic groups and carrier
Pathway 
Metabolism
Pfam 
PF01812
PID 
g1674179
RefSeq 
NP_110036.1
Swiss-Prot protein ID 
Y348_MYCPN
phylomeDB tree 
Y348_MYCPN
UniProt 
P75430
Transcription
IMAGE BROWSERS

OPERON OP138 (Genomic Overview)
Region:415152-418600

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